文献类型：期刊文献

中文题名：动态动脉硬化指数与高血压中医证型分布

英文题名：Relationship between Ambulatory Arterial Stiffness Index and TCM Differentiation of Hypertension

作者：陆玉琴[1];李应东[1];赵信科[1];王纪[1];寇宗莉[1]

第一作者：陆玉琴

机构：[1]甘肃中医学院附属医院

第一机构：甘肃中医药大学第二附属医院

年份：2013

卷号：11

期号：9

起止页码：1042

中文期刊名：中西医结合心脑血管病杂志

外文期刊名：Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease

收录：CSTPCD

语种：中文

中文关键词：高血压;中医辨证分型;动态动脉硬化指数;相应对称性动态动脉硬化指数

外文关键词：hypertension ; traditional Chinese medicine differentiation ; ambulatory arterial stiffness index ; ambulatory arterial st iff-ness index^iblood pressure variability

摘要：目的探讨高血压病患者动态动脉硬化指数、相应对称性动态动脉硬化指数与中医辨证分型的关系。方法将137例原发性高血压患者采用临床问卷调查,填写高血压患者登记表格及中医症候分级量化表后进行辨证分型,分为肝火亢盛型、阴虚阳亢型、痰湿壅盛型、阴阳两虚型,采用无创性携带式动态血压监测仪进行动态血压的监测,根据测得数据分别计算动态动脉硬化指数及相应对称性动态动脉硬化指数。所有受试者均抽空腹静脉血2mL送检,全自动生化分析仪测血脂、空腹血糖及血尿酸。用SPSS17.0软件统计分析。结果痰湿壅盛证组总胆固醇、三酰甘油、低密度脂蛋白均高于其他组,病史、年龄、体重指数亦大于其他组,但均未达到统计学意义,血尿酸高于其他组(P<0.05);肝火亢盛组全天平均舒张压高于其他证型组(P<0.05),夜间收缩压、舒张压下降率亦明显高于其他证型组(P<0.05),阴阳两虚组夜间收缩压高于肝火亢盛组,痰湿壅盛组动态动脉硬化指数、相应对称性动态动脉硬化指数高于肝火亢盛组和阴虚阳亢组(P<0.05)。结论动态动脉硬化指数、相应对称性动态动脉硬化指数可作为原发性高血压辨证分型的客观参考指标。
Objective To investigate the relationship between ambulatory arterial stiffness index （AASI）,AASI - blood pressure variability （AASI- BPVR） and traditional Chinese medicine（TCM）differentiation of Hypertension. Methods One hundred and thirty- seven patients （pts） with hypertension were enrolled in the investigation. After finished clinical questionnaire and the registration form, 137 pts were divided into 4 types,hyperactivity of liver yang, deficiency of Yin and hyperactivity of yang, excessive accumula tion of phlegm dampness,and deficiency of both Yin and Yang. The 24h ambulatory blood pressure monitoring （ABPM） were per- formed in standard positions. AASI, AASI - BPVR were computed from waking or sleeping blood pressure. The fasting blood glu cose, total cholesterol （TC）, triglyceride （TG）, high density lipoprotein cholesterol （HDL- C）, low density lipoprotein cholesterol （LDL-C）, and uric acid （UA） were tested. Results TC,TG,and LDI.- C in excessive accumulation of phlegm dampness group were higher than that in other groups. Age and body mass index were higher than that other groups. UA in excessive accumulation of phlegm dampness group was significantly higher than other groups （P〈0.05）. In hyperactivity of liver Yang, and average diastolic pressure were higher than that in other TCM syndrome types. Night blood pressure falling rate in hyperactivity of liver yang was sig- nificantly higher （P〈0.05）. While AASI and AASI - BPVR in excessive accumulation of phlegm dampness types were higher than that in hyperactivity of liver Yang and deficiency of both Yin and Yang. Conclusion The AASI,AASI - BPVR could be an objective index for differentiation of hypertension.