文献类型：期刊文献

英文题名：The effect of air pollutants on COPD-hospitalized patients in Lanzhou, China (2015-2019)

作者：Jin, Limei[1];Fang, Shuya[2];Nan, Yaxing[3];Hu, Jihong[1,4];Jin, Hua[4,5]

第一作者：靳利梅

通信作者：Hu, JH[1];Hu, JH[2];Jin, H[2];Jin, H[3]

机构：[1]Gansu Univ Chinese Med, Sch Publ Hlth, Lanzhou, Peoples R China;[2]Wenling Meteorol Bur, Wenling, Peoples R China;[3]Gansu Univ Chinese Med, Sch Hlth Management, Lanzhou, Peoples R China;[4]Minist Educ, Key Lab Dunhuang Med, Lanzhou, Peoples R China;[5]Gansu Univ Chinese Med, Clin Coll Chinese Med, Lanzhou, Peoples R China

第一机构：甘肃中医药大学公共卫生学院

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Sch Publ Hlth, Lanzhou, Peoples R China;[2]corresponding author), Minist Educ, Key Lab Dunhuang Med, Lanzhou, Peoples R China;[3]corresponding author), Gansu Univ Chinese Med, Clin Coll Chinese Med, Lanzhou, Peoples R China.|[10735]甘肃中医药大学;[10735e9d5e7087247e71b]甘肃中医药大学公共卫生学院;

年份：2024

卷号：12

外文期刊名：FRONTIERS IN PUBLIC HEALTH

收录：;Scopus(收录号：2-s2.0-85205555860);WOS:【SSCI(收录号:WOS:001330874000001)，SCI-EXPANDED(收录号:WOS:001330874000001)】；

基金：The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This study was funded by the Natural Science Foundation of Gansu Province (No. 24JRRA561, No. 23JRRA1211), the International Cooperation Project of Gansu Province (No. 20YF3WA020 and No. DHYX20-05), and the Key Researcher Project of Gansu province (No. [2023]20). The research was also supported by the Key Laboratory of Dunhuang Medicine, Ministry of Education.

语种：英文

外文关键词：air pollutants; COPD; ecological study; distributed lag non-linear model; Lanzhou

摘要：Background: Lanzhou is the largest heavy industrial city in northwest China and it is a typical geographical valley-like city. However, there are few studies on the relationship between air pollutants and COPD, and their respective sample sizes are small, resulting in inconsistent results. The aim of this study is to analyze the effects of air pollutants on COPD hospitalizations in Lanzhou, China. Methods: An ecological time series study with distributed lag non-linear model (DLNM) was used for analysis. Daily COPD hospitalization data in Lanzhou from 1 January 2015 to 31 December 2019 were collected from 25 hospitals, as well as air pollutant data and meteorological data. Results: A total of 18,275 COPD hospitalizations were enrolled. For 10 mu g/m(3 )increase in PM2.5, PM10, SO2, NO2, and 1 mg/m(3) increase in CO at lag 07 day, the RR95%CI of COPD hospitalizations were 1.048 (1.030, 1.067), 1.008 (1.004, 1.013), 1.091 (1.048, 1.135), 1.043 (1.018, 1.068), and 1.160 (1.084, 1.242), respectively. The exposure-response curves between air pollutants (except O3-8h) and COPD hospitalizations were approximately linear with no thresholds. Female, and the harmful effect of PM on aged <65 years, the effect of gaseous pollutant on those aged >= 65 years, were stronger, particularly in the cold season. Exposure to air pollutants (except O3-8h) might increase the risk of COPD hospitalizations. O3-8h has a weak and unstable effect on COPD. Conclusion Exposure to air pollutants (except O3-8h) increases the risk of COPD hospitalizations. O3-8h has a weak and unstable effect on COPD hospital admissions. The harmful effect of gaseous pollutants (except O3-8h) on COPD-hospitalized patients was stronger than that of PM.