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马铃薯代谢物龙葵素药用价值的研究现状     被引量:1

Research status of medicinal value of solanine from potato metabolite

文献类型:期刊文献

中文题名:马铃薯代谢物龙葵素药用价值的研究现状

英文题名:Research status of medicinal value of solanine from potato metabolite

作者:韩宪富[1];黄委委[1];刘俊鹏[1];潘盛强[1];李宁[1,2];罗慧英[3]

第一作者:韩宪富

机构:[1]甘肃中医药大学中医临床学院,甘肃兰州730000;[2]甘肃中医药大学附属医院康复骨科,甘肃兰州730020;[3]甘肃中医药大学药学院,甘肃兰州730000

第一机构:甘肃中医药大学中医临床学院

年份:2022

卷号:38

期号:10

起止页码:1462

中文期刊名:中国药理学通报

外文期刊名:Chinese Pharmacological Bulletin

收录:CSTPCD;;Scopus;北大核心:【北大核心2020】;CSCD:【CSCD2021_2022】;

基金:国家自然科学基金资助项目(No 82060873);甘肃省中医药管理局课题(No GZK-2019-25);甘肃中医药大学附属医院青年基金项目(No 921y-2019-08);甘肃中医药大学中青年科研基金项目(No 2305016601)。

语种:中文

中文关键词:龙葵素;抗癌;抗炎;消肿;抗肺动脉高压;研究现状

外文关键词:solanine;anti-cancer;anti-inflammation;detumescence;treatment of pulmonary hypertension;research status

摘要:马铃薯贮存不当时可出现皮肉变绿、发紫或发芽,此时其代谢物龙葵素的含量明显增加,龙葵素虽有毒,但也具有一定的药用价值,目前,研究发现,其具有抗癌、抗炎、消肿、治疗肺动脉高压及糖尿病等作用。该文通过对龙葵素医药应用研究的相关文献进行检索,系统的概括了龙葵素的药用价值,为更有效的开发利用马铃薯这一植物资源,研制高效、不良反应小的抗癌、抗炎、消肿、治疗肺动脉高压及糖尿病天然药物提供理论依据和应用基础。
Potato skin may turn green,purple or sprout when stored improperly.At this time the content of its metabolite solanine increases significantly.Although solanine is toxic,it also has certain medicinal value.It has been found that solanine has effects like anti-cancer,anti-inflammation,detumescence,treatment of pulmonary hypertension,and diabetes.This paper searches the relevant literature for the research on the medicinal application of solanine,and systematically summarizes the solanine medicinal value.For a more effective development and utilization of the plant resources,this paper hopes to provide the theoretical and application basis for the development of natural medicine with high efficiency and small adverse reactions in the treatment of cancer,inflammation,tumescence,pulmonary hypertension and diabetes.

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