文献类型：期刊文献

中文题名：基于中医传承计算平台挖掘敦煌医方《辅行诀》方剂组方用药规律

英文题名：Composition principle of prescriptions in Auxiliary Verse Medication to Viscera(Fu Xing Jue):based on traditional Chinese medicine inheritance computing system

作者：霍敏峰[1];岳娟[1];刘喜平[2];朱中博[1];李永玉[1]

第一作者：霍敏峰

机构：[1]甘肃中医药大学,甘肃兰州730000;[2]甘肃中医药大学基础医学院

第一机构：甘肃中医药大学

年份：2023

卷号：39

期号：1

起止页码：55

中文期刊名：包头医学院学报

外文期刊名：Journal of Baotou Medical College

基金：甘肃省教育厅优秀研究生“创新之星”项目(2021CXZX-744);甘肃中医药大学科研创新基金项目(KCYB2018-5);甘肃省委组织部陇原青年创新创业人才项目(2020RCXM183)。

语种：中文

中文关键词：敦煌医方;辅行诀;用药规律;中医传承计算平台;数据挖掘;

外文关键词：Dunhuang prescriptions;Fu Xing Jue(Auxiliary Verse Medication to Viscera);medication rule;Traditional Chinese Medicine Inheritance Computing System;Data mining

摘要：目的:探索《辅行诀脏腑用药法要》方剂的组方用药规律及其学术思想。方法:整理敦煌《辅行诀脏腑用药法要》方剂,采用中医传承计算平台V3.0软件对所整理方子的组方用药进行分析。结果:共涉及方剂61首,包含中药69味,药物四气以温、寒、平为主,药物五味以甘、苦、辛为主,药物归经以脾经、肺经、肾经为主,功效以补虚类药最高,药物出现频次在9次及以上的中药共有14味,排名前8位分别为:白芍(22)、炙甘草(21)、干姜(20)、生姜(14)、桂枝(14)、甘草(13)、大枣(13)、黄芩(13),药物组合中频次在6次及以上的有33组,药物关联规则33条,K-means聚类得到5个聚类。结论:通过中医传承计算平台V3.0软件揭示了《辅行诀脏腑用药法要》用药规律,治法上重视寒温并用,温补脾胃、宣肺解表、注重扶正的处方用药规律,为现代临床辨治中医疾病提供参考。
Objective:To explore the prescription and application rules and academic thoughts of Auxiliary Verse Medication to Viscera.Method:To sort out the prescriptions of Dunhuang Auxiliary Verse Medication to Viscera,and analyze the composition principle and medication rules of the sorted prescriptions using the traditional Chinese medicine inheritance computing platform V3.0 software.Results:A total of 61 prescriptions were involved,including 69 kinds of traditional Chinese medicine.The property of involved Chinese herbal medicines mostly were warm,cold,and plain,and most flavors were sweet,pungent and bitter,mainly acting on Spleen Meridian,Lung meridian and Kidney meridian to tonify deficiency and clear heat.There were 14 kinds of Chinese medicine that appeared more than 9 times,the top 8 of which were Radix Paeoniae Alba(22),Prepared Liquorice Root(21),Rhizoma Zingiberis(20),Ginger(Zingiber officinale Roscoe)(14),Ramulus Cinnamomi(14),Liquorice Root(13),Ziziphus(13),and Scutellariae Radix(13).There were 33 core combinations with frequency≥6 and 33 drug association rules were obtained,and four new prescriptions were obtained by K-means clustering analysis.Conclusion:The prescription principles and medication rules of Auxiliary Verse Medication to Viscera was revealed through the traditional Chinese medicine inheritance computing platform V3.0 software in this study.Combination of frigotherapy and pyretotherapy,warming and tonifying the spleen and stomach,dispersing lung and exterior syndrome,strengthening healthy qi are the main prescription principles and medication rules of Auxiliary Verse Medication to Viscera,which could provide a reference for modern clinical diagnosis and treatment on related diseases.