文献类型：期刊文献

英文题名：The effectiveness of acupuncture for Parkinson's disease: An overview of systematic reviews

作者：Cao, Liujiao[1,2,3,4];Li, Xiuxia[1,2,3,4];Li, Meixuan[1,2,3,4];Yao, Liang[5];Hou, Liangying[1,2,3,4];Zhang, Weiyi[1,2,3,4];Wang, Yongfeng[6];Niu, Junqiang[7];Yang, Kehu[1,2,3,4]

第一作者：Cao, Liujiao

通信作者：Niu, JQ[1];Yang, KH[2]

机构：[1]Lanzhou Univ, Sch Publ Hlth, Lanzhou 730000, Peoples R China;[2]Lanzhou Univ, Evidence Based Social Sci Res Ctr, Lanzhou 730000, Peoples R China;[3]Key Lab Evidence Based Med & Knowledge Translat G, Lanzhou 730000, Peoples R China;[4]Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, Lanzhou 730000, Peoples R China;[5]Hong Kong Baptist Univ, Chinese Med Fac, Hong Kong, Peoples R China;[6]Gansu Univ Chinese Med, Lanzhou 730000, Peoples R China;[7]Lanzhou Univ, Clin Med Coll 1, Lanzhou 730000, Peoples R China

第一机构：Lanzhou Univ, Sch Publ Hlth, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Lanzhou Univ, Clin Med Coll 1, Lanzhou 730000, Peoples R China;[2]corresponding author), Lanzhou Univ, Evidence Based Med Ctr, 199 Donggang West Rd, Lanzhou, Peoples R China.

年份：2020

卷号：50

外文期刊名：COMPLEMENTARY THERAPIES IN MEDICINE

收录：;Scopus(收录号：2-s2.0-85082746919);WOS:【SCI-EXPANDED(收录号:WOS:000535704900013)】；

基金：Supported by the Fundamental Research Funds for the Central Universities (2019jbkyzy002, 18LZUJBWZX006, lzujbky-2018-14): Evidence-based Social Sciences Research; China Medical Board Open Project Funding (CMB #17-279): Tracking and Evaluating Quality (TEQ) of Rural Health Services in NW China: Tool kits for rural clinic quality management and capacity building.

语种：英文

外文关键词：Acupuncture; Parkinson's disease; Overview; Systematic review

摘要：Objectives: Acupuncture is an alternative therapy for Parkinson's disease (PD), but its efficacy and safety are controversial. This overview aimed to summarize the existing evidence from systematic reviews (SRs) and meta-analyses (MAs) in order to assess the effectiveness of acupuncture as a treatment for PD. Methods: Seven electronic databases were searched from their inception until July 2019. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) and Assessment of Multiple Systematic Reviews 2 (AMSTAR2) checklists were used to assess evidence quality and methodological quality, respectively. The outcomes of study were calculated using mean differences (MDs) and risk ratios (RRs) with 95 % confidence intervals (CIs). A meta-analysis was performed using RevMan 5.3 software. Results: A total of 12 SRs/MAs were included. All 12 SRs/MAs had more than one critical weakness in AMSTAR 2 and were considered of critically low methodological quality. The quality of evidence was unsatisfactory according to the GRADE checklist. Meta-analyses showed that acupuncture combined with drug for the treatment of PD can significantly improve the total effectiveness rate compared with drug alone (RR = 1.25, 95 % CI 1.16-1.34, P < 0.001). It was also found that acupuncture combined with drug significantly improved the UPDRS I-IV total summed scores (WMD=-6.18, 95 % CI -10.32 to -2.04, P < 0.001) and Webster scores (WMD=-4.20, 95 % CI -7.59 to -0.81, P < 0.001). Conclusion: Acupuncture might improve the UPDRS score, Webster score, and total effective rate in treatment of PD. It might be a safe and useful adjunctive treatment for patients with PD. However, we should interpret the findings of these reviews with caution, considering the overall limited methodological and reporting quality.