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基于中医传承计算平台(V3.0)探究中医药治疗儿童功能性便秘的用药规律     被引量:1

Medication law of TCM in the treatment of children’s functional constipation based on the Traditional Chinese Medicine Inheritance Computing Platform(V3.0)

文献类型:期刊文献

中文题名:基于中医传承计算平台(V3.0)探究中医药治疗儿童功能性便秘的用药规律

英文题名:Medication law of TCM in the treatment of children’s functional constipation based on the Traditional Chinese Medicine Inheritance Computing Platform(V3.0)

作者:张雪[1];李玉霞[2];王博[1];景姬[1];闵叶[1]

第一作者:张雪

机构:[1]甘肃中医药大学研究生院,甘肃兰州730000;[2]甘肃中医药大学附属医院儿科,甘肃兰州730020

第一机构:甘肃中医药大学党委研究生工作部、研究生院

年份:2023

卷号:19

期号:5

起止页码:26

中文期刊名:中医儿科杂志

外文期刊名:Journal of Pediatrics of Traditional Chinese Medicine

基金:甘肃省中医药管理局普通中医药科研项目(GZK-2019-32)。

语种:中文

中文关键词:功能性便秘;儿童;用药规律;中医传承计算平台(V3.0);数据挖掘

外文关键词:functional constipation;children;medication law;Traditional Chinese Medicine Inheritance Compu?ting Platform(V3.0);data mining

摘要:目的基于中医传承计算平台(V3.0)分析中医药治疗儿童功能性便秘(FC)的用药规律。方法收集2012年1月至2022年3月中国知网数据库、万方数据知识服务平台及维普数据库中有关中医药治疗儿童FC的处方,通过数据挖掘,分析药物频数、性味、归经及功效,并进行关联规则和聚类分析。结果共纳入文献134篇,处方140首,涉及中药156味,使用频次排名前10位的中药为枳实、火麻仁、甘草、白术、莱菔子、陈皮、厚朴、生地黄、山楂、鸡内金;药性以温、寒性中药使用频数最高,其次为平、凉、热性中药;药味以甘、苦味中药使用频数最高,其次为辛、酸、咸味中药;药物归经前3位是脾经、胃经、肺经;药物功效以补虚、消食及理气类中药为主;常用药物组合为枳实、火麻仁,枳实、厚朴,火麻仁、甘草,枳实、莱菔子及白术、陈皮;得到核心药物组合3组。结论中医药治疗儿童FC以补脾和胃、消食化积及润肠通便为主要原则,兼以清热理气等;用药以补虚、消食、理气为主,具有寒温并用、攻补兼施的特点,为中医药治疗儿童FC提供了新的思路。
Objective To explore the medication law of traditional Chinese medicine in the treatment of children's functional constipation based on traditional Chinese Medicine Inheritance Computing Platform(V3.0).Methods Prescriptions of children with FC treated by traditional Chinese medicine were collected from China National Knowledge Network database,Wanfang Data Knowledge Service platform and VIP database from January 2012 to March 2022.Through data mining,drug frequency,TCM flavor,menstrual normalization and efficacy were analyzed,and association rules and cluster analysis were conducted.Results A total of 134 papers and 140 prescriptions were included,involving 156 traditional Chinese medicines.Among them,top 10 most frequently used herbs are Aurantii Fructus Immaturus,Cannabis Fructus,Glycyrrhizae Radix Et Rhizoma,Atractylodis Macrocephalae Rhizoma,Raphani Semen,Magnoliae Officinalis Cortex,Citri Reticulatae Pericarpium,Rehmanniae Radix,Crataegi Fructus,and Galli Gigerii Endothelium Corneum;the most frequently used herbs are warm and cold,followed by medium,cool,and hot;the most frequently used herbs are sweet and bitter,followed by pungent,sour,and salty;The top 3 drug meridians were spleen meridian,stomach meridian,and lung meridian;the drug effects were mainly in the categories of tonifying deficiency,eliminating food,and regulating qi;the commonly used drug combinations were Aurantii Fructus Immaturus,Cannabis Fructus,Aurantii FructusImmaturus Magnoliae Officinalis Cortex,Cannabis Fructus Glycyrrhizae Radix Et Rhizoma,Aurantii Fructus Immaturus,Raphani Semen,Atractylodes Macrocephala,Citri Reticulatae Pericarpium;three groups of core drug combinations were obtained.Conclusion In the treatment of FC in children with traditional Chinese medicine,it mainly focuses on supplementing the spleen and stomach,digestion and accumulation,moistening the intestine and relieving constipation,and clearing heat and regulating qi,etc.The drug was mainly used to relieve deficiency,relieve food and regulate qi,and was characterized by the combination of cold and temperature,attack and tonic,which provided a new idea for the treatment of FC in children with traditional Chinese medicine.

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