文献类型：期刊文献

中文题名：复方黑蚂蚁胶囊治疗风湿性关节炎的药效学研究

英文题名：Pharmacol dynamic Study of Compound Black Ant Capsules for treating Rheumatic Arthritis

作者：任远[1];闫秀英[2];张巨文[2];王志旺[1]

第一作者：任远

机构：[1]甘肃中医学院;[2]兰州市城关区第二人民医院

第一机构：甘肃中医药大学

年份：2001

卷号：23

期号：3

起止页码：202

中文期刊名：中成药

外文期刊名：Chinese Traditional Patent Medicine

收录：CSTPCD;;北大核心:【北大核心2000】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：复方黑蚂蚁胶囊;佐剂性关节炎;风湿性关节炎;大鼠;小鼠;抗炎作用;镇痛作用;中医药治疗

外文关键词：Compound Black Ant Capsules; adjuvant arthritis; anti inflammatory effect; analgesic effect

摘要：目的 :研究复方黑蚂蚁胶囊的药理作用。方法 :制造大鼠佐剂性关节炎模型、小鼠迟发性超敏反应 (DTH)模型和醋酸扭体疼痛模型 ,观察复方黑蚂蚁胶囊的药理作用。结果 :复方黑蚂蚁胶囊可明显抑制完全弗氏佐剂所致大鼠原发性和继发性炎症 ;对DNCB引起小鼠耳肿胀有明显抑制作用 ;可明显减少醋酸所致小鼠扭体次数。结论 :复方黑蚂蚁胶囊对大鼠佐剂性关节炎有抗炎作用 ;对DNCB所致小鼠DTH反应有明显抑制作用 ;
Objective: To study the pharmacologic effects of Compound Black Ant Capsules. Methods: The adjuvant arthritis model of rats (AA rats), delayed hypersensitivity (DTH) model and the pain model induced by acetic acid in mice were used. Results: Compound Black Ant Capsules could significanty inhibit the primary and secondary inflammation of rats induced by the complete Freund's adjuvant, inhibit the ear edema induced by DNCB in mouse and decrease the number of writhes of mouse caused by acetic acid.Conclusion: Compound Black Ant Capsules have the anti inflammatory effect on DTH arthritis and analgesic effect, and inhibit mouse DTH reaction induced by DNCB.