文献类型：期刊文献

英文题名：The Antioxidant Action of Astragali radix: Its Active Components and Molecular Basis

作者：Yao, Juan[1];Peng, Ting[1];Shao, Changxin[1];Liu, Yuanyuan[2];Lin, Huanhuan[1];Liu, Yongqi[2]

第一作者：姚娟

通信作者：Yao, J[1];Liu, YQ[2]

机构：[1]Gansu Univ Chinese Med, Coll Pharm, Lanzhou 730101, Peoples R China;[2]Gansu Univ Chinese Med, Coll Basic Med, Lanzhou 730013, Peoples R China

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Coll Pharm, Lanzhou 730101, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Coll Basic Med, Lanzhou 730013, Peoples R China.|[107351d2d02a88e1f325f]甘肃中医药大学基础医学院（敦煌医学研究所）;[10735]甘肃中医药大学;[1073501e14fb35863569f]甘肃中医药大学药学院（西北中藏药协同创新中心办公室）;

年份：2024

卷号：29

期号：8

外文期刊名：MOLECULES

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001211349800001)】；

基金：No Statement Available

语种：英文

外文关键词：Astragali radix; antioxidant; astragalus polysaccharides; flavonoids compounds; saponins compounds

摘要：Astragali radix is a traditional medicinal herb with a long history and wide application. It is frequently used in prescriptions with other medicinal materials to replenish Qi. According to the classics of traditional Chinese medicine, Astragali radix is attributed with properties such as Qi replenishing and surface solidifying, sore healing and muscle generating, and inducing diuresis to reduce edema. Modern pharmacological studies have demonstrated that some extracts and active ingredients in Astragali radix function as antioxidants. The polysaccharides, saponins, and flavonoids in Astragali radix offer beneficial effects in preventing and controlling diseases caused by oxidative stress. However, there is still a lack of comprehensive research on the effective components and molecular mechanisms through which Astragali radix exerts antioxidant activity. In this paper, we review the active components with antioxidant effects in Astragali radix; summarize the content, bioavailability, and antioxidant mechanisms; and offer a reference for the clinical application of Astragalus and the future development of novel antioxidants.