文献类型：期刊文献

英文题名：Comparative analysis of Ligusticum chuanxiong from Gansu and Sichuan using the fingerprint technique and HS-SPME-GC-MS combined with chemometric analysis

作者：Zhang, Jialing[1];Liu, Juanjuan[1];Chen, Yiyang[1];Wang, Liangcai[1];Li, Ke[1];Tu, Gonghan[1];Ma, Xiaohui[1];Jin, Ling[1,2,3,4]

第一作者：张娟丽;张家莉;张晋陇;张进丽;张佳丽

通信作者：Jin, L[1];Jin, L[2];Jin, L[3];Jin, L[4]

机构：[1]Gansu Univ Chinese Med, Sch Pharm, Lanzhou, Gansu, Peoples R China;[2]Northwest Chinese Tibetan Med Collaborat Innovat C, Lanzhou, Gansu, Peoples R China;[3]Long Yao Ind Innovat Res Inst, Lanzhou, Gansu, Peoples R China;[4]Gansu Engn Res Ctr Evaluat Protect & Utilizat Rare, Lanzhou, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Sch Pharm, Lanzhou, Gansu, Peoples R China;[2]corresponding author), Northwest Chinese Tibetan Med Collaborat Innovat C, Lanzhou, Gansu, Peoples R China;[3]corresponding author), Long Yao Ind Innovat Res Inst, Lanzhou, Gansu, Peoples R China;[4]corresponding author), Gansu Engn Res Ctr Evaluat Protect & Utilizat Rare, Lanzhou, Gansu, Peoples R China.|[10735]甘肃中医药大学;

年份：2026

卷号：21

期号：4

外文期刊名：PLOS ONE

收录：;Scopus(收录号：2-s2.0-105037615777);WOS:【SCI-EXPANDED(收录号:WOS:001754730200024)】；

基金：This work was supported by the China Agriculture Research System of MOF and MARA (CARS-21); Strategic Research and Consulting Project of China Academy of Engineering (GS2021ZDA06); Gansu Province Science and Technology Plan Project: Major Science and Technology Special (23ZDFA013-1); and Gansu Provincial Science and Technology Plan Project: Science and Technology Special Touring Special (23CXNA0042).

语种：英文

摘要：Ligusticum chuanxiong (LC) is an important medicinal herb widely used in traditional Chinese medicine (TCM). The variety cultivated in Gansu Province, known as chuanxiong (Xixiong, LX), exhibits distinct morphological characteristics compared with LC from other regions. In this study, we performed a comprehensive comparative analysis of LC and LX. Odor and color were quantified using an electronic nose and a colorimeter, respectively. Volatile components were profiled by headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry (HS-SPME-GC-MS), while high-performance liquid chromatography (HPLC) was used to quantify chemical constituents and establish chromatographic fingerprint profiles. Pearson correlation analysis was further conducted to elucidate the relationships among chromaticity parameters, odor and other phenotypic traits, and chemical constituents, as well as their associations with altitude. Results showed that LX had significantly greater dry weight, diameter, and other morphological parameters than LC. LX powder displayed a brown hue, whereas LC powder appeared yellowish-brown. LC exhibited higher response values for the W1S and W2S sensors compared with LX. HPLC analysis revealed that the contents of ligustilide (LI), senkyunolide I (SI), senkyunolide H (SH), and 3-butylphthalide (3B) were significantly higher in LC than in LX (p < 0.01), whereas the senkyunolide (SA) was significantly lower in LC (p < 0.05). HS-SPME-GC-MS detected 82 compounds in LX and 62 compounds in LC, with 34 compounds shared between them. Significant correlations were observed among altitude, chromaticity, odor, and chemical composition. This study provides a systematic characterization of the differences between the collected LC and LX, offering insights that may enhance the market competitiveness of LX, promote optimal utilization of regional resources, and support the sustainable development of the LX industry in Gansu Province.