文献类型：期刊文献

中文题名：醋甘遂、复方大承气汤、生长抑素联合治疗麻痹性肠梗阻

英文题名：Triple Therapy with Vinegar Kansui Radix,Fufang Dachengqi Tang and Somatostatin in Combined Treatment of Paralytic Ileus

作者：易剑锋[1,2];叶蓁蓁[3];潘海邦[1,2];易华[2];王新平[2];赵春霖[2];董小鹏[1,2]

第一作者：易剑锋

机构：[1]甘肃中医学院临床医学院,兰州730000;[2]甘肃中医学院附属医院,兰州730000;[3]西北民族大学,兰州730000

第一机构：甘肃中医药大学临床医学院

年份：2015

卷号：21

期号：10

起止页码：182

中文期刊名：中国实验方剂学杂志

外文期刊名：Chinese Journal of Experimental Traditional Medical Formulae

收录：CSTPCD;;北大核心:【北大核心2014】；CSCD:【CSCD_E2015_2016】；

语种：中文

中文关键词：麻痹性肠梗阻;醋甘遂;复方大承气汤;生长抑素

外文关键词：paralytic ileus; vinegar Kansui Radix; Fufang Dachengqi Tang; somatostatin

摘要：目的:探讨醋甘遂、复方大承气汤、生长抑素联合治疗麻痹性肠梗阻的作用及疗效。方法:回顾分析甘肃中医学院附属医院诊治的70例麻痹性肠梗阻患者的临床资料,按照治疗方法不同分为治疗组(30例)和对照组(40例),对照组采用常规治疗加复方大承气汤保留灌肠,治疗组在对照组基础上联合使用醋甘遂和生长抑素。观察两组症状、体征、胃肠减压量、临床症状改善时间、体温和白细胞计数恢复时间及疗效。结果:治疗组腹痛腹胀、排气排便的缓解率高于对照组(P<0.05);两组患者在恶心呕吐缓解方面无明显差异;治疗组胃肠减压量低于对照组(P<0.01);治疗组腹痛缓解时间、腹胀缓解时间、呕吐缓解时间、肠鸣音恢复时间、排气、排便恢复时间及进食时间均短于对照组(P<0.01);治疗组体温及白细胞计数恢复正常时间短于对照组(P<0.01);治疗组临床痊愈率及总有效率均高于对照组(73.3%VS 22.5%,96.7%VS 87.5%,P<0.05)。结论:醋甘遂、复方大承气汤和生长抑素联合应用可显著提高麻痹性肠梗阻疗效,具有症状改善快、胃肠功能恢复快、感染易控制等优点。
Objective： The aim of this study was to evaluate the efficacy of triple combination therapy of vinegar Kansui Radix,Fufang Dachengqi Tang and somatostatin in the treatment of paralytic ileus. Method： The clinical data of 70 patients with paralytic ileus,who were treated at affiliated hospital of Gansu university of traditional Chinese medicine（TCM）,were analyzed. They were divided into treatment group（30 cases） and control group（40 cases） according to the treatment. The control group was received combination treatment of routine treatment and Fufang Dachengqi Tang retention-enema. The treatment group was received combination therapy of vinegar Kansui Radix and somatostatin on the basis of the control group. Clinical symptoms,signs,gastrointestinal decompression amount,improvement time of clinical symptom,recovery time of body temperature and leukocyte number and clinical efficacy were observed and compared between the two groups. Result： The post-treatment remission rate of abdominal pain,abdominal distension,flatus and defecation were higher in treatment group than in control group（P〈0. 05）. The post-treatment remission rate of nausea and vomiting showed no statistically difference in both two groups. The post-treatment gastrointestinal decompression amount in treatment group was lower than in control group（P〈0. 01）. The improvement time of clinical symptom including abdominal pain,abdominal distension,vomiting,intestinal sound recovery,flatus,defecation and eating in treatment group were shorter than control group（P〈0. 01）. The recovery time of body temperature and leukocyte number in treatment group were shorter than that in control group（P〈0. 01）. The clinical curative rate and total effective rate in treatment group were higher than in control group（73. 3% VS 22. 5%,96. 7% VS 87. 5%,P〈0. 05）.Conclusion： Combination therapy of vinegar Kansui Radix,Fufang Dachengqi Tang and somatostatin can improve the efficacy of paralytic ileus,with the advantage of fast improvement of clinical symptom,quick recovery of gastrointestinal function and easy control of infection.