文献类型：期刊文献

英文题名：Delayed uveitis after implantable Collamer lens Implantation caused by COVID-19 infection: a case report

作者：Sun, Yan[1];Wu, Huiying[2];Yan, Xingke[3];Zhou, Jibo[4];Niu, Tianyue[1];Zhu, Jie[5]

第一作者：Sun, Yan

通信作者：Zhu, J[1]

机构：[1]Lanzhou Bright Eye Hosp, Dept Refract Surg, Lanzhou 730030, Gansu, Peoples R China;[2]Nanchang Bright Eye Hosp, Dept Refract Surg, Nanchang 330038, Jiangxi, Peoples R China;[3]Gansu Univ Chinese Med, Lanzhou 730030, Gansu, Peoples R China;[4]Shanghai Jiao Tong Univ, Ninth Peoples Hosp, Dept Ophthalmol, Sch Med, Shanghai 200011, Peoples R China;[5]Gansu Baoshihua Hosp, Dept Gastroenterol, 733,Fuli West Rd, Lanzhou 730060, Gansu, Peoples R China

第一机构：Lanzhou Bright Eye Hosp, Dept Refract Surg, Lanzhou 730030, Gansu, Peoples R China

通信机构：[1]corresponding author), Gansu Baoshihua Hosp, Dept Gastroenterol, 733,Fuli West Rd, Lanzhou 730060, Gansu, Peoples R China.

年份：2025

卷号：17

期号：5

起止页码：3565

外文期刊名：AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001504577200031)】；

基金：This work was supported by the Lanzhou Science and Technology Planning Project (2022-3-67; 2022-3-20) ; Gansu Province Innovation-driven Boosting Project (GXH2024-0328-2) and Lanzhou Health and Hygiene Industry Research Project (A2024027) and Gansu Province Science and Technology Plan Project (23CXGA0115) .

语种：英文

外文关键词：High myopia; ICL crystal implantation surgery; rainbow eyelash inflammation; ankylosingspondylitis

摘要：This report presents a case of uveitis secondary to ankylosing spondylitis (AS) with abnormal exudative deposits and pigment adhesion on the surface of an implantable Collamer lens (ICL) in a highly myopic eye following coronavirus disease 2019 (COVID-19) infection. The etiology and treatment were analyzed. A 22-year-old male presented with decreased visual acuity in the right eye, having undergone bilateral ICL implantation for high myopia 22 months prior. During the COVID-19 pandemic, he developed ocular exudation, pigment deposition, and vision deterioration, with a confirmed diagnosis of AS. Therapeutic interventions included anti-inflammatory, antiviral, and corticosteroid therapies. Postoperative uveitis secondary to AS following ICL implantation represents a rare complication. COVID-19 infection and concurrent systemic autoimmune disorders were identified as risk factors for secondary iridocyclitis. Immunological testing confirmed AS diagnosis. Treatment with sodium hyaluronate eye drops, ganciclovir ophthalmic gel, and systemic corticosteroids improved symptoms; however, persistent punctate exudates and pigment deposits on the ICL surface exhibited limited resolution. For patients with systemic autoimmune diseases or virus-induced uveitis undergoing ICL implantation, preoperative immunological screening should be actively performed to minimize postoperative complications. Early comprehensive therapy is critical to prevent progressive vision loss and rare transparency alterations of the ICL surface caused by pigment-laden exudates.