文献类型：期刊文献

英文题名：Systematic assessment of complications after robotic-assisted total versus distal gastrectomy for advanced gastric cancer: A retrospective propensity score-matched study using Clavien-Dindo classification

作者：Wang, Wen-Jie[1,2,4];Li, Rui[1,2];Guo, Chang-An[1,3,5];Li, Hong-Tao[5];Yu, Jian-Ping[5];Wang, Jing[5,6];Xu, Zi-Peng[1,5];Chen, Wei-Kai[5,6];Ren, Zhi-Jian[1,2];Tao, Peng-Xian[1,2];Zhang, Ya-Nan[1,2];Wang, Chen[1,2];Liu, Hong-Bin[1,3]

第一作者：Wang, Wen-Jie

通信作者：Liu, HB[1];Wang, C[2]

机构：[1]Lanzhou Univ, Clin Med Coll 2, 82 Chuiying Gate, Lanzhou 730030, Gansu, Peoples R China;[2]Lanzhou Univ, Dept Gen Surg, Hosp 2, 82 Chuiying Gate, Lanzhou 730030, Gansu, Peoples R China;[3]940th Hosp Joint Logist Support Force Chinese Peo, Dept Gen Surg, Lanzhou 730050, Gansu, Peoples R China;[4]Key Lab Stem Cells & Gene Drugs Gansu Prov, Lanzhou 730050, Gansu, Peoples R China;[5]Lanzhou Univ, Hosp2, Dept Emergency, Lanzhou 730030, Gansu, Peoples R China;[6]Gansu Univ Tradit Chinese Med, Clin Med Coll, Lanzhou 730000, Gansu, Peoples R China

第一机构：Lanzhou Univ, Clin Med Coll 2, 82 Chuiying Gate, Lanzhou 730030, Gansu, Peoples R China

通信机构：[1]corresponding author), Lanzhou Univ, Clin Med Coll 2, 82 Chuiying Gate, Lanzhou 730030, Gansu, Peoples R China;[2]corresponding author), Lanzhou Univ, Dept Gen Surg, Hosp 2, 82 Chuiying Gate, Lanzhou 730030, Gansu, Peoples R China.

年份：2019

卷号：71

起止页码：140

外文期刊名：INTERNATIONAL JOURNAL OF SURGERY

收录：;Scopus(收录号：2-s2.0-85072787128);WOS:【SCI-EXPANDED(收录号:WOS:000495693600029)】；

基金：This study was supported by Cuiying Graduate Supervisor Applicant Training Program of Lanzhou University Second Hospital, Huimin plan of Ministry of Science and Technology of the People's Republic of China (2012GS620101), and Key Science and Technology Foundation of Gansu Province (2011GS04390).

语种：英文

外文关键词：Gastric cancer; Robot-assisted distal gastrectomy; Robot-assisted total gastrectomy; Postoperative complications; Clavien-Dindo classification

摘要：Background: Despite increasing evidence demonstrated robot-assisted distal gastrectomy (RADG) is safe and feasible for the treatment of advanced gastric cancer (AGC), robot-assisted total gastrectomy (RATG) remains a challenging procedure due to its technical difficulties and possible postoperative complications (POCs). This study aimed to systematically evaluate POCs following RATG. Methods: Between January 2017 and January 2019, 319 AGC patients with pathological stage T2-4aN0-3M0 who underwent RADG or RATG were enrolled. POCs were stratified using the Clavien-Dindo classification. Oneto-one propensity score matching was performed to reduce confounding differences. Results: After matching, 266 patients met the criteria for further analysis. Ultimately, 64 patients (24.1%) who developed POCs had 126 clinical manifestation events. Overall the POCs rate was significantly greater after RATG in comparison with RADG (29.3% vs. 18.8%; P = 0.045), and more major POCs (Clavien-Dindo grade >= IIIa) were observed in the RATG group (14.3% vs. 5.3%; P = 0.013). The POCs were then classified into local and systemic POCs. The rates of local POCs (35.3% vs. 19.5%; P = 0.004) and systemic POCs (24.8% vs. 15.0%; P = 0.046) were significantly higher in the RATG group than the RADG group. Subgroup analysis showed that the anastomotic leakage rate was higher after RATG (5.3% vs. 0.8%; P = 0.031), whereas the remaining POCs were similar between the two groups. Patients with higher POCs significantly had longer postoperative length of stay (R = 0.895, P = 0.003). Multivariate analysis confirmed age, extent of resection, and TNM stage were risk factors for all POCs. Conclusions: These findings demonstrated that RATG is technically feasible and safe for treatment of AGC with acceptable morbidity and mortality rates. The POCs rate of RATG was higher than RADG, especially for anastomotic leakage. More effective anastomotic techniques are needed in RATG to prevent leakage.