文献类型：期刊文献

中文题名：郑氏热补针法辅助治疗中晚期胃癌脾胃虚寒证34例临床观察

英文题名：Clinical observation on 34 cases of ZHENG’s heat reinforcing needling manipulation in adjunctive treatment of middle-late gastric cancer with deficiency-cold in spleen and stomach syndrome

作者：郑欣[1];杜小正[2];何文洁[2];李梦莘[2];王娜娜[2];王功臣[3]

第一作者：郑欣

机构：[1]河西学院医学院,甘肃张掖734000;[2]甘肃中医药大学针灸推拿学院,甘肃兰州730101;[3]甘肃中医药大学附属医院肿瘤科,甘肃兰州730020

第一机构：河西学院医学院,甘肃张掖734000

年份：2021

卷号：38

期号：6

起止页码：64

中文期刊名：甘肃中医药大学学报

外文期刊名：Journal of Gansu University of Chinese Medicine

基金：国家中医药管理局甘肃郑氏针法学术流派传承工作室项目(2305135901)。

语种：中文

中文关键词：胃癌;脾胃虚寒证;热补针法;盐酸羟考酮缓释片;疼痛数字评分法评分;卡氏评分;临床疗效

外文关键词：gastric cancer;deficiency-cold in spleen and stomach syndrome;heat reinforcing needling manipulation;oxycodone hydrochloride prolonged-release tablets;numerical rating scale(NRS)score;Karnofsky performance scale(KPS)score;clinical efficacy

摘要：目的观察郑氏热补针法辅助治疗中晚期胃癌脾胃虚寒证的临床疗效。方法将72例中晚期胃癌脾胃虚寒证患者采用随机数字表法分为对照组和治疗组,各36例,2组各脱落2例,最终2组均纳入34例。对照组给予西医常规治疗,治疗组在对照组治疗方法的基础上给予郑氏热补针法。针刺治疗每日1次,6 d为1个疗程,疗程间休息1 d,共治疗2个疗程。治疗结束后比较2组的临床疗效、日均疼痛爆发次数、镇痛持续时间、盐酸羟考酮缓释片用量、不良反应发生率及治疗前后的疼痛数字评分法(NRS)评分、卡氏(KPS)评分。结果对照组总有效率和总不良反应发生率分别为67.6%(23/34),52.9%(18/34),治疗组分别为88.2%(30/34),29.4%(10/34),2组比较差异均有统计学意义(P<0.05);治疗后治疗组疼痛爆发次数及盐酸羟考酮缓释片用量均明显减少,镇痛持续时间明显延长,2组比较差异有统计学意义(P<0.05);治疗后2组NRS评分均明显降低,KPS评分均明显升高,与同组治疗前比较差异有统计学意义(P<0.05),且治疗组改善作用更明显,与对照组治疗后比较差异均有统计学意义(P<0.05)。结论郑氏热补针法辅助治疗中晚期胃癌脾胃虚寒证临床疗效肯定,镇痛效果较好,且不良反应低,值得临床推广应用。
Objective To observe the clinical efficacy of ZHENG’s heat reinforcing needling manipulation in adjunctive treatment of middle-late gastric cancer with deficiency-cold in spleen and stomach syndrome.Methods Seventy-two cases of middle-late gastric cancer with deficiency-cold in spleen and stomach syndrome were divided into control group and treatment group according to random number table method,with 36 cases in each group.There were 2 drop-out cases in each group,and 34 cases were included in each group finally.The control group was given routine Western medicine treatment,on this basis,the treatment group was given ZHENG’s heat reinforcing needling manipulation.Acupuncture treatment was performed once a day,6 days as 1 course of treatment,rest for 1 day between courses of treatment,totally 2 courses of treatment.The clinical efficacy,the average times of daily pain attacks,analgesia duration,dosage of oxycodone hydrochloride prolonged-release tablets,and incidence of adverse reactions after treatment,along with numerical rating scale(NRS)score,and Karnofsky performance scale(KPS)score before and after treatment were compared between the 2 groups.Results The total effective rate and incidence of total adverse reactions were 67.6%(23/34)and 52.9%(18/34)in the control group,and 88.2%(30/34)and 29.4%(10/34)in the treatment group,respectively,and the differences were statistically significant between the 2 groups(P<0.05).After treatment,the times of pain attacks and the dosage of oxycodone hydrochloride prolonged-release tablets in the treatment group significantly reduced,and analgesia duration significantly prolonged,and the differences were statistically significant between the 2 groups(P<0.05).After treatment,NRS scores in both groups decreased significantly,while KPS scores in both groups increased significantly,and the differences were statistically significant compared with those in the same group before treatment(P<0.05),moreover,the improving effect in the treatment group was more significant,and the differences were statistically significant compared with those in the control group after treatment(P<0.05).Conclusion It has definite clinical efficacy,good analgesic effect,and low adverse reactions to use ZHENG’s heat reinforcing needling manipulation in adjunctive treatment of middle-late gastric cancer with deficiency-cold in spleen and stomach syndrome,which deserves clinical promotion and application.