文献类型：期刊文献

英文题名：Impact of preoperative intramuscular injection of nalbuphine on postoperative pain in elderly patients received arthroplasty

作者：Zhang, Xu[1];Shi, Songbo[1];Wang, Tingting[2];Di, Wenfei[1];Fan, Lizhen[1];Yang, Yuping[1];Qian, Yaowen[1]

第一作者：Zhang, Xu

通信作者：Qian, YW[1]

机构：[1]Gansu Prov Hosp, Dept Orthoped, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Lanzhou, Gansu, Peoples R China

第一机构：Gansu Prov Hosp, Dept Orthoped, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Orthoped, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.

年份：2019

卷号：12

期号：4

起止页码：3982

外文期刊名：INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000466494200099)】；

语种：英文

外文关键词：Nalbuphine; elderly patients; analgesia; hip arthroplasty

摘要：Objective: To investigate the effect of preoperative nalbuphine intramuscular injection on postoperative pain in elderly patients who received total hip replacement or hemiarthroplasty. Methods: A total of 60 elderly patients who received total hip or hemi-hip arthroplasty during October 2016 to April 2017 in Gansu Provincial Hospital were included in the study. They were randomized into the control group and the nalbuphine group. The nalbuphine group received intramuscular nalbuphine injection at 8: 00 pm in the day before the day for operation, while the control group was given placebo. We observed and recorded the visual analogue score (VAS) at 30 minutes (T1), 2 hours (T2), 6 hours (T3) and 12 hours (T4) after surgery and meanwhile recorded quality of life and postoperative adverse reaction at day 1 after admission, one day before operation, 24 hours after operation and 48 hours after operation. Results: Compared with the control group, the nalbuphine group had lower visual analogue sores and higher quality of life scores at each time observed. No significant adverse reaction happened in both of the two groups. Conclusion: Nalbuphine pretreatment is useful for postoperative pain management of elder patients who receive hip arthroplasty.