详细信息

中医药与脑缺血后海马神经干细胞增殖与分化    

The roles of traditional Chinese medicine in the proliferation and differentiation of hippocampal neural stem cells after cerebral ischemia

文献类型:期刊文献

中文题名:中医药与脑缺血后海马神经干细胞增殖与分化

英文题名:The roles of traditional Chinese medicine in the proliferation and differentiation of hippocampal neural stem cells after cerebral ischemia

作者:黄生辉[1,2,3];巩婷[4];李妍怡[4]

第一作者:黄生辉

机构:[1]甘肃中医药大学中西医结合学院;[2]甘肃中医药大学附属医院神经内科;[3]甘肃中医药大学中西医结合研究所,兰州730000;[4]甘肃省中医院脑病科

第一机构:甘肃中医药大学中西医结合学院

年份:2018

卷号:27

期号:3

起止页码:284

中文期刊名:中国组织化学与细胞化学杂志

外文期刊名:Chinese Journal of Histochemistry and Cytochemistry

收录:CSTPCD;;CSCD:【CSCD_E2017_2018】;

基金:甘肃省中医院立项国家自然基金(地区基金)项目(81460686);重大疑难疾病(脑梗死)中西医临床协作试点项目

语种:中文

中文关键词:中医药;脑缺血;海马神经干细胞;Notch信号通路;Wnt信号通路

外文关键词:Traditional Chinese medicine;hippocampal neural stem cells;cerebral ischemia;notch signaling pathway;Wnt signaling pathway

摘要:单味中药、中医复方和针灸等中医疗法对神经干细胞的增殖、分化研究是当前的研究热点。本文对脑缺血后单味中药、中医复方和针灸中药促进海马神经干细胞增殖、分化作用研究进行综述,通过对notch和wnt信号通路调控脑缺血后海马神经干细胞增殖、分化机制研究进行总结,为中医药在脑缺血后海马神经干细胞增殖、分化及相关机制的研究提供科学理论依据和参考。
It has become a hot research topic to explore the roles of Chinese herbal medicine,simple or compound recipe,and acupuncture therapy in the proliferation and differentiation of neural stem cells.This article reviewed recent progress on utilizating Chinese medicine to promote hippocampal neural stem cells proliferation and differentiation.It also summarized current understanding on the regulation mechanism of hippocampal neural stem cell proliferation and differentiation through notch and W nt signal pathway after cerebral ischemia.Thus,it serves as a reference to study the applications of Chinese medicine in hippocampal neuron regeneration after cerebral ischemia.

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