文献类型：期刊文献

中文题名：聚类分析与主成分分析在颈椎病中医证型规范化研究中的应用

英文题名：Cluster analysis and principal component analysis in traditional medical syndrome types and standardization of cervical spondylosis

作者：王春晓[1];谢兴文[2];李宁[1]

第一作者：王春晓

机构：[1]甘肃中医学院,甘肃省兰州市730000;[2]甘肃省中医院,甘肃省兰州市730050

第一机构：甘肃中医药大学

年份：2011

卷号：15

期号：43

起止页码：8083

中文期刊名：中国组织工程研究与临床康复

外文期刊名：Journal of Clinical Rehabilitative Tissue Engineering Research

收录：北大核心:【北大核心2008】；CSCD:【CSCD_E2011_2012】；

基金：甘肃省中医药管理局;中医药科研课题立项(07-GIK-13)~~

语种：中文

中文关键词：聚类分析;主成分分析;颈椎病;规范化;中医证型

摘要：背景:目前对于颈椎病的中医分型相对单一,缺乏各型颈椎病一一分型辨治的中医特色与特点。以往各型颈椎病分型主要是以个人经验总结,缺乏客观化依据,尚需数理化的方法的验证。目的:运用聚类分析和主成分分析方法调查颈椎病中医证型的分布特点。方法:根据颈椎病患者的临床表现设计调查表,收集575例颈椎病患者的症状、体征、舌脉等四诊信息,采用聚类分析和主成分分析法对调查表中98个常见症状进行分析。结果与结论:聚类分析得出8类证候:湿热侵袭,痰湿阻络,气血两虚,肝肾亏虚,脾肾阳虚,血瘀气滞,寒湿痹阻,肝脾两虚。颈椎病病机复杂,虚实并见,其基本的病机是以"邪实"为主,主要表现为气滞、湿热、寒湿、痰湿,并见血瘀之邪;而正虚主要表现为阴虚、阳虚、气虚和血虚。提示聚类分析和主成分分析用于中医证型的分类研究具有一定科学性。
BACKGROUND：Recently,the classification of cervical spondylosis is relatively single,lacking the features of Chinese medicine syndrome types in dialectically treating the disease.The previous methods of classifying cervical spondylosis are the summaries of personal experiences without objective base.Therefore,it is significant to investigate syndrome classification using cluster analysis and principal component analysis.OBJECTIVE：To investigate the distribution traits in cervical spondylosis according to different symptom types of traditional Chinese medicine using cluster analysis and principal analysis.METHODS：The questionnaire was designed according to the clinical manifestations in cervical spondylosis patients.Symptoms,clinical signs,tongue,pulse and other diagnostic messages of 575 patients were collected,to analyze 98 common symptoms using cluster analysis and principal component analysis.RESULTS AND CONCLUSION：According to the results of cluster analysis,the disease could be divided into eight categories：dampness-heat energizer,phlegm and wet resistance channels and collaterals,deficiency of qi and blood,deficiency of liver-kidney yin,deficiency of the spleen and kidney-yang,blood stasis and qi stagnation,cold dampness resistance channels and collaterals,deficiency of liver and spleen.We found that most of their disease mechanisms were ＂state of evil domination＂,which was caused by qi stagnation,dampness-heat,cold dampness,phlegm-dampness,blood stasis.Meanwhile,because of the existence of asthenia of healthy qi,the main representation was deficiency of yin,deficiency of yang,deficiency of qi and deficiency of blood.Cluster analysis and principle component analysis are scientific to some extent used in the research of traditional Chinese medical syndrome types.