文献类型：期刊文献

中文题名：消定膏商品化瓶颈问题的新解决方案

英文题名：The New Solution to the Bottleneck Problem of Xiaoding Ointment Commercialization

作者：韩静[1];程芳[2];张晓刚[2];杨锡仓[2];窦霞[2];靳子明[2]

第一作者：韩静

机构：[1]甘肃中医药大学附属医院研究生部,甘肃兰州730020;[2]甘肃省中药炮制及质控工程技术研究中心,甘肃兰州730020

第一机构：甘肃中医药大学第二附属医院

年份：2019

卷号：17

期号：3

起止页码：142

中文期刊名：中国中医药现代远程教育

外文期刊名：Chinese Medicine Modern Distance Education of China

基金：甘肃省中医药管理局科研课题【No.GZK-2015-17】;甘肃中医药大学中青年科研基金项目【No.ZQ2017-3】;甘肃省中药现代制药工程研究院自立项目

语种：中文

中文关键词：消定膏;医院制剂;二次开发;新方案;商品化

外文关键词：Xiaoding ointment;hospital preparations;secondary development;new scheme;commercialization

摘要：消定膏是陇上中医骨伤科长期使用的品牌中药制剂,临床研究表明对骨折、损伤等病症的疗效良好。药学研究表明其药理、急性与慢性毒性实验、制备工艺、质量标准等均已有相关研究。然而消定膏却迟迟不能开发为新药,其主要原因是该制剂的稳定性差、有效期太短、包装落后、患者使用不便。针对制约消定膏商品化的瓶颈问题,课题组拟定了两套新实验方案,并取得了一定进展,有助于加快其商品化进程。
Xiaoding ointment is a branded Chinese medicine preparation used for a long time in orthopedics department of Gansu province,the clinical researches showed that it was effective for fracture,injury and other diseases.The pharmaceutical studies showed that the pharmacology,acute and chronic toxicity experiments,preparation technology and quality standards had been studied.The main reasons for the delay in the development of xiaoding ointment as a new drug are poor stability,short validity period,backward packaging and inconvenience to patients.Aiming at the bottleneck problem that restricts the commercialization of xiaoding ointment,the research group has drawn up two new experimental schemes and made some progress,which can help speed up its commercialization process.