文献类型：期刊文献

中文题名：益智口服液对智能迟缓儿童智力结构的影响(英文)

英文题名：Effect of yizhi koufuye on intelligence structure in children with intelligence retardation

作者：史正刚[1];韩涛[1];张士卿[1];杜风珍[2];丁吉芳[2]

第一作者：史正刚

机构：[1]甘肃中医学院儿科教研室,甘肃省兰州市730000;[2]甘肃省康复中心,甘肃省兰州市730000

第一机构：甘肃中医药大学中医临床学院

年份：2005

卷号：9

期号：12

起止页码：220

中文期刊名：中国临床康复

外文期刊名：Chinese Journal of Clinical Rehabilitation

收录：北大核心:【北大核心2004】；CSCD:【CSCD_E2011_2012】；

语种：中文

中文关键词：中药疗法;口服液;治疗;智力;发育障碍

摘要：背景:儿童智能迟缓是由分类智商中操作智商、言语智商等项目组成总智商的智力结构的低下,一些研究证实中药的某些复方组合成份对其有较好的干预效应。目的:观察益智口服液对智能迟缓儿童智力结构的影响。设计:以患儿为研究对象的同期对照研究。单位:一所省级的中医学院儿科教研室,一所省级康复中心。对象:病例选择2002-01/07,在甘肃省康复中心医院和甘肃中医学院附属医院门诊,以CCMD-Ⅱ-R提出的智能迟缓诊断标准确诊为智能迟缓者的6～16岁兰州市城关区辅读学校学生,能够接受药物及训练治疗,非先天遗传性染色体疾病者74例,男47例,女27例。分为治疗组33例,对照组20例,单纯教育训练组21例。方法:治疗组33例均服益智口服液,小于10岁每次服15mL,10～14岁每次20mL,14岁服以上者每次服25mL,3次/d,接受特殊教育训练。对照组20例患儿均口服乙-吡咯烷酮乙酰胺,0.4g/次,3次/d,接受特殊教育训练,单纯教育训练组21例患儿只接受与治疗组、对照组患儿相同的特殊教育。3个月为一疗程。采用中国-韦氏儿童智力量表(C-WISC)及专用工具评估3组治疗前后总智商及分类智商中操作智商、言语智商智力测试,进行组间对照比较。主要观察指标:3组总智商改善情况及言语及操作智商提高值。结果:74例入选,无脱落。①总智商改善情况:治疗?
BACKGROUND:The intelligence retardation in children refers to hypo intelligen ce structure of full intelligence quotient(FIQ) composed of performance intellig ence quotient(PIQ) and verbal intelligence quotient(VIQ).It is verified in some researches that some of compound formulas provide better intervention on it. OBJECTIVE:To observe the effect of yizhi koufuye on intelligence structure in children with intelligence retardation. DESIGN:Homochronous controlled study based on children. SETTING:Pediatric department in a provincial college of traditional Chinese me dicine and one provincial rehabilitation center. PARTICIPANTS:The cases were selected in Rehabilitative Central Hospital in Gan su Province and Clinic of the Hospital Affiliated to Gansu College of Traditiona l Chinese Medicine from January to July 2002.They were 74 students in Fudu Schoo ls in Chenguan District,Lanzhou City,aged varied from 6 to 16 years,diagnosed as intelligence retardation according to CCMD II R proposed Intelligence Retarda tion Diagnostic Standards,and they were able to accept medical and training trea tment and were absent of congenital hereditary chromosome disorders.Of those,47 cases were males and 27 cases females.They were divided into treatment group of 33 cases,the control of 20 cases and simple educational training group of 21 cas es. METHODS:In treatment group of 33 cases,yizhi koufuye was administrated and was taken 15 mL each time for children younger than 10 years old,20 mL for those be tween 10 to 14 years old and 25 mL for those over 14 years old. In addition,the special educational training was applied.In the control of 20 cases, oral applic ation of piracetam was prescribed,0.4 g per time,3 times a day and the special e ducational training was applied additionally.In simple educational training grou p of 21 cases,the children only received special education same as those in trea tment group and the control.Three months made one session.Chinese Wechsler Inte lligence Scale for Children(C WISC) and specific devices were used to assess FI Q and PIQ and VIQ in classified IQ in 3 groups before and after treatments,and t he control comparisons were carried on among groups. MAIN OUTCOME MEASURES:Improvement of FIQ and improved values of VIQ and PIQ in 3 groups. RESULTS:Totally 74 cases were selected and no one lost. Improvement of FIQ:In treatment group,there were 44.7±9.8 and 51.8±11.5 before and after treatment r espectively,t=2.701,P< 0.01;In the control,there were 43.8±14.0 and 51.0±13.6 before and after treatment respectively,t =1.680,P >0.05;In simple educational t raining group,there were 41.6±7.8 and 45.2±10.6 before and after treatment res pectively,t =1.561 and P >0.05. Improved values of VIQ:It was 8.1±5.5 in treatm ent group,5.3±3.9 in the control and 4.8±4.8 in simple educational training gr oup.P< 0.05 compared with the results in treatment group.Improved values of PIQ: It was 4.0±3.6 in treatment group and P< 0.05 compared with 1.7±2.2 in the co ntrol and simple educational training group. Improving extent of VIQ was 8.1±5. 5 and of PIQ was 4.0±3.6 in treatment group,P< 0.01. CONCLUSION:Yizhi koufuye improves markedly FIQ of children with intelligence r etardation and for the classified IQ,the improving extent of VIQ is superior to that of PIQ.