文献类型：期刊文献

英文题名：Prevalence and factors associated with atrial fibrillation in older patients with obstructive sleep apnea

作者：Wang, Huanhuan[1,2];Li, JianHua[3,4];Gao, Yinghui[5];Chen, Kaibing[6];Gao, Yan[7];Guo, JingJing[8];Shi, Min[1];Zou, Xiao[3,4];Xu, Weihao[3,4];Zhao, LiBo[3,4];Su, Xiaofeng[2];Wang, Yabin[3,4];Liu, Juan[3,4];Xu, Hu[3,4];Kong, Xiaoxuan[3,4];Lin, Junling[9];Qian, Xiaoshun[1];Han, Jiming[2];Liu, Lin[1]

第一作者：Wang, Huanhuan

通信作者：Qian, XS[1];Liu, L[1];Han, JM[2]

机构：[1]Chinese Peoples Liberat Army Gen Hosp, Dept Pulm & Crit Care Med, Med Ctr 2, Beijing, Peoples R China;[2]Yanan Univ, Med Coll, Yanan, Shaanxi, Peoples R China;[3]Chinese Peoples Liberat Army Gen Hosp, Cardiol Dept, Med Ctr 2, Beijing, Peoples R China;[4]Chinese Peoples Liberat Army Gen Hosp, Natl Clin Res Ctr Geriatr Dis, Beijing, Peoples R China;[5]Peking Univ Int Hosp, PKU UPenn Sleep Ctr, Beijing, Peoples R China;[6]Gansu Univ Chinese Med, Sleep Ctr, Affiliated Hosp, Lanzhou, Gansu, Peoples R China;[7]960Th Hosp PLA, Dept Gen Practice, Jinan, Shandong, Peoples R China;[8]Peking Univ Peoples Hosp, Sleep Med Ctr, Dept Resp & Crit Care Med, Beijing, Peoples R China;[9]Capital Med Univ, Dept Resp & Crit Care Med, Beijing Chaoyang Hosp, Beijing, Peoples R China

第一机构：Chinese Peoples Liberat Army Gen Hosp, Dept Pulm & Crit Care Med, Med Ctr 2, Beijing, Peoples R China

通信机构：[1]corresponding author), Chinese Peoples Liberat Army Gen Hosp, Dept Pulm & Crit Care Med, Med Ctr 2, Beijing, Peoples R China;[2]corresponding author), Yanan Univ, Med Coll, Yanan, Shaanxi, Peoples R China.

年份：2022

卷号：22

期号：1

外文期刊名：BMC GERIATRICS

收录：;Scopus(收录号：2-s2.0-85126655579);WOS:【SSCI(收录号:WOS:000768837100005)，SCI-EXPANDED(收录号:WOS:000768837100005)】；

基金：This study was supported by Open Subject of National Clinical Research Center for Geriatric Diseases (NCRCG-PLAGH-2018008); Military Health Care Project (19BJZ34); Youth Program for Military Medicine of Chinese PLA General Hospital (QNC19054). The funders had not directly role in the design.

语种：英文

外文关键词：Obstructive sleep apnea; Atrial fibrillation; Older people; Prevalence; China

摘要：Purpose This study sought to identify the prevalence and factors associated with atrial fibrillation (AF) in older patients with obstructive sleep apnea (OSA) in China. Methods This was an explorative cross-sectional study. Between January 2015 and October 2017, we continuously recruited 1285 older patients with OSA who underwent overnight polysomnography from sleep centers of multiple hospitals. They were assessed using 12-lead ECG or 24-h dynamic ECG, and their baseline demographics, clinical characteristics, sleep parameters, and medical history were determined. Multivariate binary logistic regression analysis was used to investigate the factors related to AF in these older patients with OSA. Results The clinician classified 122 (9.5%) patients as having AF. The prevalence of AF significantly increased with age (P < 0.05) but did not significantly differ between the mild, moderate, and severe OSA groups. Additionally, the prevalence of paroxysmal AF was 7.2% among the overall study population, and it increased with OSA severity or advanced age (P < 0.05). Persistent AF was noted in 2.3% participants, and the prevalence also increased with age. The logistic regression analysis showed that age (OR = 1.054, 95%CI: 1.027-1.018, P < 0.001), history of drinking (OR = 1.752, 95%CI: 1.070-2.867, P < 0.05), chronic heart disease (OR = 1.778, 95%CI: 1.156-2.736, P < 0.01), diabetes mellitus (OR = 1.792, 95%CI: 1.183-2.713, P < 0.01), and reduced diastolic function (OR = 2.373, 95%CI = 1.298-4.337, P < 0.01) were relevant to AF among participants with OSA. Conclusion The prevalence of AF is significantly common in older patients with OSA. Age, history of drinking, chronic heart disease, diabetes mellitus, and reduced diastolic function are independently related to AF in these patients.