文献类型：期刊文献

英文题名：Maternal Factors for Intrauterine Growth Retardation: Systematic Review and Meta-Analysis of Observational Studies

作者：Yang, Liu[1,2];Feng, Lufang[3,4,5];Huang, Lijuan[2,6];Li, Xuejiao[2];Qiu, Wenwen[2,6];Yang, Kehu[3,4,5];Qiu, Jie[2];Li, Haihong[1,2]

第一作者：Yang, Liu

通信作者：Li, HH[1];Qiu, J[2];Li, HH[2];Yang, KH[3];Yang, KH[4];Yang, KH[5]

机构：[1]Lanzhou Univ, Sch Nursing, Lanzhou 730011, Gansu, Peoples R China;[2]Gansu Prov Matern & Child Care Hosp, Lanzhou 730050, Gansu, Peoples R China;[3]Lanzhou Univ, Evidence Based Social Sci Res Ctr, Sch Publ Hlth, Lanzhou 730000, Gansu, Peoples R China;[4]Lanzhou Univ, Evidence Based Med Ctr, Sch Basic Med Sci, Lanzhou 730000, Gansu, Peoples R China;[5]Key Lab Evidence Based Med & Knowledge Translat Ga, Lanzhou 730000, Gansu, Peoples R China;[6]Gansu Univ Chinese Med, Sch Nursing, Lanzhou 730000, Gansu, Peoples R China

第一机构：Lanzhou Univ, Sch Nursing, Lanzhou 730011, Gansu, Peoples R China

通信机构：[1]corresponding author), Lanzhou Univ, Sch Nursing, Lanzhou 730011, Gansu, Peoples R China;[2]corresponding author), Gansu Prov Matern & Child Care Hosp, Lanzhou 730050, Gansu, Peoples R China;[3]corresponding author), Lanzhou Univ, Evidence Based Social Sci Res Ctr, Sch Publ Hlth, Lanzhou 730000, Gansu, Peoples R China;[4]corresponding author), Lanzhou Univ, Evidence Based Med Ctr, Sch Basic Med Sci, Lanzhou 730000, Gansu, Peoples R China;[5]corresponding author), Key Lab Evidence Based Med & Knowledge Translat Ga, Lanzhou 730000, Gansu, Peoples R China.

年份：2023

卷号：30

期号：6

起止页码：1737

外文期刊名：REPRODUCTIVE SCIENCES

收录：;Scopus(收录号：2-s2.0-85146623446);WOS:【SCI-EXPANDED(收录号:WOS:000918044700001)】；

基金：AcknowledgementsThe authors gratefully acknowledge the financial supports by the National Social Science Foundation of China under Grant number No. 19ZDA142.Availability of Data and MaterialsNot applicable.Code AvailabilityNot applicable.

语种：英文

外文关键词：Intrauterine growth retardation; Risk factors; Meta-analysis; Review

摘要：Intrauterine growth retardation (IUGR) is a major complication of pregnancy and is the second leading cause of perinatal morbidity and mortality. The etiology of IUGR is multifactorial and the maternal factors are easily identifiable and modifiable. The present study aimed to perform a meta-analysis to identify the association between various maternal factors and IUGR. Eight electronic databases (PubMed, Cochrane, Embase, CIHNAL Plus, CNKI, VIP database, CBM, and WanFang database) were searched from their inception until July 2020. Eligibility screening, data extraction, and quality assessment of the retrieved articles were conducted independently by two reviewers. The Newcastle-Ottawa Quality Assessment Form and the Joanna Briggs Institute critical appraisal tool were used to evaluate the quality of included studies. The outcomes of study were calculated by OR with 95%CI. The study protocol was registered with PROSPERO (No. CRD42020210615). A total of 15 studies were included, with a sample size range from 152 to 9372. The quality of included studies ranged from moderate to high. The pooled results identified seven factors: smoking (OR = 1.62, 95%CI 1.38-1.90), primiparity (OR = 1.64, 95%CI 1.20-2.24), and prepregnancy.BMI < 18.5 (OR = 1.98, 95%CI 1.29-3.03), anemia (OR = 2.01, 95%CI 1.44-2.82), hypoproteinemia (OR = 2.91, 95%CI 1.94-4.36), pregnancy-induced hypertension (OR = 3.45, 95%CI 1.80-6.58), and maternal gestational weight gain (OR = 2.51, 95%CI 1.88-3.35). The present study identified several maternal factors for IUGR: smoking, primiparity, prepregnancy BMI < 18.5, poor gestational weight gain, PIH, anemia, and hypoproteinemia. The result could serve to generate risk factors prediction models, improve the management and education for child-bearing or early pregnant women.