文献类型：期刊文献

中文题名：驻高原武警官兵不同时间血清生化指标与情绪状态变化

英文题名：Changes of serum biochemical indexes and mood state of armed police soldiers over time in plateau

作者：王欢欢[1,2,3];韩继明[2];刘霖[1,3];钱昆[4];陈开兵[5];温若卿[6]

第一作者：王欢欢

机构：[1]解放军总医院第二医学中心呼吸与危重症医学科,北京100853;[2]延安大学医学院,陕西延安716000;[3]解放军总医院国家老年疾病临床医学研究中心,北京100853;[4]解放军北京老干部活动中心,北京100853;[5]甘肃中医药大学附属医院睡眠中心,甘肃兰州730000;[6]甘肃中医药大学,甘肃兰州730000

第一机构：解放军总医院第二医学中心呼吸与危重症医学科,北京100853

年份：2021

卷号：42

期号：12

起止页码：1243

中文期刊名：解放军医学院学报

外文期刊名：Academic Journal of Chinese PLA Medical School

收录：CSTPCD;;北大核心:【北大核心2020】；

基金：国家老年疾病临床研究中心2018开放课题(NCRCG-PLAGH-2018008);解放军总医院军事医学青年项目(QNC19054);解放军总医院第二医学中心专项科研课题立项资助(ZXD2008)。

语种：中文

中文关键词：高原;军事人员;血脂;糖化血红蛋白;简明心境量表

外文关键词：plateau;military personnel;serum lipids;glycated hemoglobin;brief profile of mood states

摘要：背景我国西部地区高原地域辽阔,资源丰富,民族众多,亟需部队官兵驻扎防守。受高原特殊的地理环境及气候因素影响,个体的生理、心理会产生一系列改变。目的通过观察驻高原武警官兵不同时间血脂、血糖指标与情绪状态的动态变化,发现其相互关系,以维护保障高原驻训武警官兵健康。方法本研究选取2019年11月-2021年4月进驻西部地区(约海拔4000 m)某部武警官兵150人为研究对象,分别在其高原驻训的第3个月、6个月、12个月时进行血生化检查及问卷调查,收集数据进行相关分析。结果武警官兵驻守高原期间糖化血红蛋白(glycosylated hemoglobin,HbA1c)异常率达14.7%,且随驻高原时间的延长异常率显著下降(P<0.05)。血清生化指标三酰甘油(triglyceride,TG)随高原驻训时间的延长显著增高,HbA1c随之明显降低(P<0.05);高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)和低密度脂蛋白胆固醇(low-density lipoprotein cholesterol,LDL-C)在高原驻训6个月时较高原驻训3个月时有所下降,在高原驻训12个月时又显著上升(P<0.05)。消极情绪随高原驻训时间延长而显著增长(P<0.05),积极情绪有所波动。高原驻训6个月后,与正常HbA1c组相比,高HbA1c组武警官兵紧张、愤怒、疲劳、抑郁、慌张、消极情绪及情绪总分得分显著升高;精力、自尊感及积极情绪得分显著降低(P均<0.05)。进一步相关分析发现驻高原3个不同时间段武警官兵血清TG、总胆固醇(total cholesterol,TC)、LDL-C含量与紧张、愤怒、疲劳、抑郁、慌乱消极情绪均呈正相关,与精力、自尊感积极情绪呈负相关(P<0.05)。结论武警官兵血清TG随高原驻训时间的延长显著升高,HbA1c水平则相反,HDL-C和LDL-C先下降后升高。紧张、愤怒、疲劳、抑郁、慌乱消极情绪随高原驻训时间延长呈加重态势;精力、自尊感积极情绪逐渐增长直至高原驻训第6个月,之后下降。在高原驻训期间武警官兵血清TG、TC、LDL-C水平与消极情绪均呈正相关,与积极情绪呈明显负相关,血脂水平越高,消极情绪越显著,积极情绪下降越明显。
Background The western region in China has a vast plateau with abundant resources and numerous ethnic groups.It is urgent that troops need to be stationed for defense.However,affected by the special geographical environment and climatic factors of the plateau,a series of changes will occur in the individual’s physiology and psychology.Objective To observe the dynamic changes of blood lipid,blood glucose indexes and mood states of soldiers over time in plateau and investigate the correlation between them,so as to guarantee the health of soldiers stationed on plateau.Methods From November 2019 to April 2021,we recruited 150 soldiers who were trained in the western region with altitude of 4000 meters.Their blood biochemical examination and questionnaires were carried out at the third month,the sixth month,and the first year of their plateau training,data were collected for correlation analysis.Results The abnormal rate of HbA1 c was 14.7%during the period of soldiers stationed in plateau,and it decreased significantly with the prolongation of time on the plateau(P<0.05).The serum TG concentration of armed police soldiers significantly increased with the extension of training time on the plateau,while the HbA1 c concentration significantly decreased(P<0.05).The concentration of HDL-C and LDL-C decreased at 6 months compared with that of 3 months of altitude training on the plateau,while it significantly increased at 1 year of altitude training(P<0.05).The negative emotions of armed police soldiers increased with the prolongation of altitude training(P<0.05),and the positive emotions fluctuated.Compared with the normal HbA1 c group,the scores of tension,anger,fatigue,depression,panic,negative mood and mood states in the high HbA1 c group increased significantly,and the scores of energy,self-esteem and positive mood decreased at 6 months on the plateau(P<0.05).Further correlation analysis showed that the concentration of TG,TC and LDL-C were positively correlated with tension,anger,fatigue,depression,panic,and negative mood,and negatively correlated with energy and self-esteem(P<0.05).Conclusion The serum TG of armed police soldiers increases significantly with the prolongation of training time on the plateau,while the HbA1 c level is on the contrary.HDL-C and LDL-C decrease first and then increase.The negative mood of nervousness,anger,fatigue,depression and panic increase with the prolongation of training time.The positive mood of energy and self-esteem gradually increase until the sixth month on the plateau,and then decrease significantly.Moreover,the serum TG,TC and LDL-C levels of armed police soldiers are positively correlated with negative emotions,and negatively correlated with positive emotions.