详细信息
当归挥发油β-环糊精包合物的制备工艺及定性分析 被引量:15
Preparation Technology and Qualitative Analysis for β-Cyclodextrin Inclusion Compound of Angelica Oil
文献类型:期刊文献
中文题名:当归挥发油β-环糊精包合物的制备工艺及定性分析
英文题名:Preparation Technology and Qualitative Analysis for β-Cyclodextrin Inclusion Compound of Angelica Oil
作者:朱冉[1];郭玫[1,2];魏舒畅[1];余晓晖[1];杨霞[1]
第一作者:朱冉
机构:[1]甘肃中医学院,甘肃兰州730000;[2]甘肃省高校中(藏)药化学与质量省级重点实验室,甘肃兰州730000
第一机构:甘肃中医药大学
年份:2012
卷号:35
期号:8
起止页码:1322
中文期刊名:中药材
外文期刊名:Journal of Chinese Medicinal Materials
收录:CSTPCD;;Scopus;北大核心:【北大核心2011】;CSCD:【CSCD2011_2012】;PubMed;
基金:国家自然科学基金(30960037);兰州科技计划项目(2010-1-160)
语种:中文
中文关键词:当归挥发油;β-环糊精;包合
外文关键词:Angelica oil; β-cyclodextrin; Inclusion complex
摘要:目的:优选制备当归挥发油β-环糊精包合物的最佳方法。方法:采用单因素筛选及正交实验相结合,以包合率为指标,优选最佳包合工艺。结果:最佳包合方法为饱和水溶液法,包合条件为当归挥发油与β-环糊精的比例为1∶8,β-环糊精与水的比例为1∶6,搅拌时间4 h。结论:优选的包合工艺操作简便、工艺稳定、挥发油包合率较高。
Objective:To optimize the preparation process of β-cyclodextrin(β-CD) inclusion compound of Angelica oil.Methods: Single factor experiment and orthogonal design were used together,oil inclusion rate was used as an index,then chose the best preparation technology.Results: The optimal method was saturated solution method.The preparation condition for inclusion was as follows: the ratio of Angelica oil to β-CD was(1∶ 8),the ratio of β-CD to water was(1∶ 6) and the stirring time was 4 h.Conclusion: The preparation procedure of inclusion volatile oil is simple,stable,reliable and high inclusion rate.
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