文献类型：期刊文献

英文题名：Meta-analysis of outcomes after total knee arthroplasty in patients with rheumatoid arthritis and osteoarthritis

作者：Zhang, An -Ren[1,2];Cheng, Qing-Hao[1];Yang, Yong-Ze[1];Yang, Xin[1];Zhang, Zhuang-Zhuang[1];Guo, Hong-Zhang[1,3]

第一作者：Zhang, An -Ren

通信作者：Guo, HZ[1]

机构：[1]Gansu Univ Tradit Chinese Med, Clin Med Coll 1, Lanzhou, Peoples R China;[2]Gansu Prov Hosp, Lanzhou, Peoples R China;[3]Gansu Prov Hosp, 204 Donggang West Rd, Lanzhou 730000, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Prov Hosp, 204 Donggang West Rd, Lanzhou 730000, Peoples R China.

年份：2024

卷号：47

期号：1

起止页码：43

外文期刊名：ASIAN JOURNAL OF SURGERY

收录：;Scopus(收录号：2-s2.0-85172869020);WOS:【SCI-EXPANDED(收录号:WOS:001155290300001)】；

语种：英文

外文关键词：Rheumatoid arthritis; Osteoarthritis; Total knee arthroplasty; Meta -analysis

摘要：The purpose of this study was to compare the difference in functional scores and the incidence of complications after TKA between RA and osteoarthritis. The PubMed, MedLine, The Cochrane Library, Embase and Web of Science databases were searched for all clinical studies up to 15 March 2023 comparing outcomes after total knee replacement in patients with RA and OA, with two review authors independently screening the literature. A total of 7,820,115 (knee-counted) cases were included in 34 studies. The results of meta -analysis showed that the scores of the RA group were lower than that of the osteoarthritis group in the postoperative knee joint score [MD=-2.72,95%CI(-5.06,-0.38),P=0.02] and the postoperative knee joint function score [MD=-11.47,95%CI(-16.55,-6.39),P<0.00001], and the difference was statistically significant. The incidence of deep venous thrombosis (OR=0.84,95% CI(0.79,0.90),P<0.00001) and pulmonary embolism (OR=0.84,95%CI(0.78,0.91),P<0.00001) were significantly lower in RA than in osteoarthritis (P<0.00001). Compared with patients with osteoarthritis, patients with rheumatoid arthritis have lower knee society scores and functional scores after total knee arthroplasty, and a higher risk of prosthetic infection, loosening, and revision, but TKA can still effectively reduce pain in RA patients, Improve function and quality of life without increasing the risk of lower extremity venous thrombosis and pulmonary embolism. Therefore, total knee replacement can be used as a treatment option for patients with rheumatoid arthritis who have not responded to conservative treatment. Patients should fully understand the benefits and possible risks of total knee replacement and develop an individualized treatment plan. (c) 2023 Asian Surgical Association and Taiwan Robotic Surgery Association. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).