文献类型：期刊文献

英文题名：Association Between Paraspinal Muscle Parameters and Single-Segment Degenerative Lumbar Spondylolisthesis

作者：Liu, Shuang[1,2];Shi, Qi[1,2];Da, Wei-Wei[1];Xue, Chun-Chun[3];Chen, Lin[1];Li, Yu-Nan[1,4];Xue, Yong-Peng[1,4];Du, Wen-Lan[1];Li, Xiao-Feng[1]

第一作者：Liu, Shuang

通信作者：Li, XF[1]

机构：[1]Shanghai Univ Tradit Chinese Med, Shanghai Municipal Hosp Tradit Chinese Med, Dept Orthoped, 274 Zhijiang Middle St, Shanghai 200071, Peoples R China;[2]Shanghai Univ Tradit Chinese Med, LongHua Hosp, Inst Spinal Dis, Shanghai, Peoples R China;[3]Shanghai Univ Tradit Chinese Med, Shanghai Municipal Hosp Tradit Chinese Med, Dept Pain, Shanghai, Peoples R China;[4]Gansu Univ Tradit Chinese Med, Sch Clin Tradit Chinese Med, Lanzhou, Gansu, Peoples R China

第一机构：Shanghai Univ Tradit Chinese Med, Shanghai Municipal Hosp Tradit Chinese Med, Dept Orthoped, 274 Zhijiang Middle St, Shanghai 200071, Peoples R China

通信机构：[1]corresponding author), Shanghai Univ Tradit Chinese Med, Shanghai Municipal Hosp Tradit Chinese Med, Dept Orthoped, 274 Zhijiang Middle St, Shanghai 200071, Peoples R China.

年份：2025

卷号：50

期号：12

起止页码：841

外文期刊名：SPINE

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001497893900003)】；

基金：The National Natural Science Foundation of China supported this research through the General Program (82374473, 81973881). In addition, funding was provided by the Medical Innovation Research Special Project of the Shanghai Science and Technology Innovation Action Plan (21Y11921300, 22Y11922500), as well as the Shanghai Medical Innovation Development Foundation Future Plan (WLJH2021ZY-GZS001/ZLZX001/MZY034, WL-XJRY-2021003K, WLJH2022ZY-ZYY001).

语种：英文

外文关键词：Paraspinal muscle; degenerative lumbar spondylolisthesis; multifidus; erector spinae; psoas major relative; cross-sectional area at; infiltration rate; magnetic resonance imaging; spinal canal anteroposterior diameter; low back pain

摘要：Study Design.A retrospective, cross-sectional cohort study.Objective.This study aimed to investigate the association between paraspinal muscle parameters and single-segment degenerative lumbar spondylolisthesis (DLS).Summary of Background Data.The relationship between lumbar paraspinal muscle morphology and single-segment DLS remains unclear.Methods.A retrospective review was conducted on 115 patients with L4/5 single-segment DLS and 105 subjects without DLS. Two independent investigators assessed the relative cross-sectional area and fat infiltration rate of the multifidus, erector spinae, and psoas major at L3/4, L4/5, and L5/S1 levels, comparing these measurements between the 2 groups. In addition, binary logistic regression analysis was performed with DLS as the dependent variable to analyze the relative cross-sectional area and fat infiltration rate of different paraspinal muscles. Within the DLS group, the correlation between paraspinal muscle characteristics and the anteroposterior diameter of the spinal canal was examined.Results.The fat infiltration rate of multifidus, erector spinae, and psoas major was higher in the DLS group than in the control group, whereas the relative cross-sectional area of multifidus and psoas major was lower in the DLS group. Binary logistic regression analysis revealed a significant correlation between the fat infiltration rate of multifidus and psoas major and DLS. The relative cross-sectional area of multifidus and erector spinae was significantly smaller below the affected segment in the DLS group compared with the control group. A significant positive correlation was observed between the relative cross-sectional area of multifidus and erector spinae and the anteroposterior diameter of the spinal canal.Conclusion.There is a close association between paraspinal muscle degeneration and single-segment DLS, with an increased relative cross-sectional area of the multifidus and psoas major possibly being risk factors for single-segment DLS. The restoration or enhancement of paraspinal muscle function could potentially serve as a pivotal target for the prevention and treatment of single-segment DLS.Level of Evidence.Level III.