文献类型：期刊文献

中文题名：1990-2019年中国胃癌疾病负担及变化趋势分析

英文题名：Disease burden and trend of stomach cancer in China, 1990-2019

作者：汪哲[1,2,3];包云丽[1,2];李娜[1,2];唐海茹[1,2];卢利霞[2];马俊[3];于晓辉[2]

第一作者：汪哲

机构：[1]甘肃中医药大学第一临床医学院,甘肃兰州730000;[2]中国人民解放军联勤保障部队第九四〇医院消化内科;[3]中国人民解放军联勤保障部队第九四〇医院基础医学实验室,甘肃省干细胞与基因药物重点实验室

第一机构：甘肃中医药大学临床医学院

年份：2023

卷号：50

期号：12

起止页码：2128

中文期刊名：现代预防医学

外文期刊名：Modern Preventive Medicine

收录：CSTPCD;;北大核心:【北大核心2020】；

基金：甘肃省非感染性肝病临床医学研究中心(21JR7RA017);甘肃省重点研发项目(20YF8FA099)。

语种：中文

中文关键词：胃癌;疾病负担;中国;Joinpoint模型

外文关键词：Stomach cancer;Burden of disease;China;Joinpoint model

摘要：目的 描述和分析我国1990-2019年胃癌疾病负担状况及流行趋势,为我国胃癌防控提供理论依据。方法 利用2019年全球疾病数据负担数据库,提取中国胃癌疾病负担数据;基于Joinpoint回归模型估算胃癌的标化发病率、死亡率、DALY率在各时段的变化趋势及特征,Excel 2019软件进行数据整理。结果 (1)2019年我国胃癌的发病率43.09/10万;死亡率29.64/10万;DALY率690.76/10万。相比1990年,发病率、死亡率分别上升0.61%、14.83%,DALY率下降0.87%。(2)男性标化发病率、标化死亡率、标化DALY率均高于女性。(3)疾病负担指标随着年龄的升高而升高,≥80岁时均达到高峰。(4) 1990-2019年,我国胃癌的标化发病率、死亡率、DALY率的平均年度变化百分比(AAPC)值分别是-0.7%(95%CI为-0.9~-0.5)、-1.9%(95%CI为-2.1~-1.7)、-2.2%(95%CI为-2.3~-2),均P<0.05,各项标化率均呈下降趋势。结论 1990-2019年,我国胃癌的粗发病率、粗死亡率呈上升趋势,粗DALY率呈下降趋势。标化率均呈下降趋势。男性的各项疾病负担指标明显高于女性;疾病负担集中在高龄人群,而我国的人口老龄化逐渐加重,因此,胃癌防控已面临严峻的局面。
Objective To describe and analyze the burden and prevalence of stomach cancer diseases in China from 1990 to 2019,and to provide theoretical basis for preventing and controlling stomach cancer.Methods The burden of stomach cancer in China was extracted from the Global Burden of Disease Data Database 2019.The trend and characteristics of normalized incidence,mortality and DALY rate of stomach cancer were estimated based on Joinpoint regression model,and the data were sorted by Excel 2019 software.Results The incidence rate of stomach cancer in 2019 was 43.09/100000.Mortality rate was 29.64/100000.The DALY rate was 690.76/100000.Compared with 1990,the incidence rate and mortality respectively increased by 0.61% and 14.83%,and the DALY rate decreased by 0.87%.The standard morbidity,standard mortality and standard DALY rate of males were higher than those of females.The index of disease burden increased with the increase of age,reaching the peak at≥80 years.From 1990 to 2019,the average annual percentage change(AAPC)values of the standardized incidence,mortality and DALY rate of stomach cancer were 0.7%(95%CI:0.9-0.5),1.9%(95%CI:2.1-1.7),2.2%(95%CI:2.3-2)respectively with all P<0.05,and all the standardized rates showed a downward trend.Conclusion The rude morbidity and rude mortality of stomach cancer show an increasing tendency in our country between 1990 and 2019,and the rude DALY rate show a decreasing tendency.The normalization rate show a downward trend.The indicators of disease burden of males are significantly higher than those of females.The disease burden is concentrated in the advanced age group,and the aging population in China is aggravating gradually.Therefore,the prevention and control of stomach cancer is facing a serious situation.