文献类型：期刊文献

英文题名：A Meta-analysis of the Clinical Efficacy of the Head-of-Bed Elevation for Patients With Acquired Brain Injury

作者：Che, Ying[1,3,4];Lu, Tingting[4];Wang, Tianming[5];Zhao, Hairong[1];Song, Xulin[1];Zhan, Qing[1];Zhang, Chengzu[1];Pan, Haibang[5];Yang, Kehu[3];Wang, Bo[1,2]

第一作者：Che, Ying

通信作者：Wang, B[1];Wang, B[2];Yang, KH[3]

机构：[1]Gansu Univ Tradit Chinese Med, Nursing Dept, Lanzhou, Peoples R China;[2]Lanzhou Univ, Evidence Based Med Ctr, Sch Basic Med Sci, Lanzhou 730000, Peoples R China;[3]Lanzhou Univ, Evidence Based Med Ctr, Sch Basic Med Sci, Lanzhou, Peoples R China;[4]Gansu Prov Hosp, Inst Clin Res & Evidence Based Med, Lanzhou, Peoples R China;[5]Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Tradit Chinese Med, Nursing Dept, Lanzhou, Peoples R China;[2]corresponding author), Lanzhou Univ, Evidence Based Med Ctr, Sch Basic Med Sci, Lanzhou 730000, Peoples R China;[3]corresponding author), Lanzhou Univ, Evidence Based Med Ctr, Sch Basic Med Sci, Lanzhou, Peoples R China.|[10735]甘肃中医药大学;

年份：2023

卷号：55

期号：3

起止页码：91

外文期刊名：JOURNAL OF NEUROSCIENCE NURSING

收录：;Scopus(收录号：2-s2.0-85159335209);WOS:【SSCI(收录号:WOS:000983557200005)，SCI-EXPANDED(收录号:WOS:000983557200005)】；

基金：This review was supported by project of the "Innovation Star" program for outstanding graduate students of Gansu Provincial Department of Education, China (2022CXZX-750).

语种：英文

外文关键词：acquired brain injury; head-of-bed elevation; intracranial pressure; meta-analysis

摘要：BACKGROUND: Acquired brain injury is caused by traumatic or nontraumatic factors and causes changes in cognition. Several reviews have described the influence of the head-of-bed (HOB) elevation on clinical indexes such as intracranial pressure (ICP) and cerebral perfusion pressure (CPP). However, the conclusions were inconsistent. Therefore, we aimed to evaluate the effects of HOB elevation in the care of the patients with ABI. METHODS: Two researchers independently screened the literature and extracted data. We searched PubMed, EMBASE, the Cochrane Library, Web of Science, and the Chinese Biological Literature Database to collect eligible randomized controlled trials published after September 2021. Reporting quality and methodological quality of the included studies were assessed by using the Preferred Reporting Items for Systematic Reviews and Meta-analysis and the Cochrane risk-of-bias tool. RESULTS: Eight studies were included in the meta-analysis. The results showed that, compared with the flat position, HOB elevation of 30 degrees or 45 degrees can significantly reduce ICP (mean difference [MD], -2.40 mm Hg; 95% confidence interval [CI], -3.19 to -1.61; P < .00001). However, there were no statistical differences in CPP (MD, -1.09; 95% CI, -3.93 to 1.75; P = .45), degree of disability at 90 days (relative risk, 1.01; 95% CI, 0.94-1.08; P = .83), and mean arterial pressure (MD, -0.44; 95% CI, -10.27 to 9.93; P = .93). CONCLUSION: Head-of-bed elevation of 30 degrees can reduce ICP and maintain CPP, and may be an effective noninvasive nursing practice for the prognosis and rehabilitation of ABI patients. Owing to the lack of high-quality, large-sample randomized controlled trials, more rigorous trials are needed to support this conclusion.