文献类型：期刊文献

英文题名：Detection of methyl parathion using a novel oxidized polylevodopa fluorescence nanosensor

作者：Zhou, Delai[1];Xu, Jian[2];Zeng, Fankui[2];Yang, Fude[1]

第一作者：Zhou, Delai

通信作者：Yang, FD[1];Zeng, FK[2]

机构：[1]Gansu Univ Chinese Med, Coll Pharm, Lanzhou, Peoples R China;[2]Chinese Acad Sci, Lanzhou Inst Chem Phys, Res Ctr Nat Med & Chem Metrol, Lanzhou, Peoples R China

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Coll Pharm, Lanzhou, Peoples R China;[2]corresponding author), Chinese Acad Sci, Lanzhou Inst Chem Phys, Res Ctr Nat Med & Chem Metrol, Lanzhou, Peoples R China.|[1073501e14fb35863569f]甘肃中医药大学药学院（西北中藏药协同创新中心办公室）;[10735]甘肃中医药大学;

年份：2026

卷号：14

外文期刊名：FRONTIERS IN CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001853616400001)】；

基金：The author(s) declared that financial support was received for this work and/or its publication. This work was supported by the Graduate Innovation and Entrepreneurship Fund Project of Gansu University of Chinese Medicine (2026CXCY-041), 2025 Gansu Provincial Drug Regulatory Science Research Project (2025GSMPA072), the earmarked fund for Gansu Agriculture Research System (GSARS-05), the China Agriculture Research System (Grant No. CARS-9), Lanzhou planning project of science and technology (Grant No. 2023-3-39) and the Gansu Planning Projects on Science and Technology (Grant No. 23CXNJ0013).

语种：英文

外文关键词：fluorescent sensor; inner filter effect; methyl parathion; oxidized polylevodopa; pesticide detection

摘要：Introduction An ultra-sensitive fluorescence sensing system was constructed for methyl parathion (MP) detection using oxidized polymer of levodopa (L-DOPA) as a novel fluorescent probe.Methods L-DOPA was first polymerized under alkaline conditions to form black L-DOPA polymer (PDOPA), and then H2O2 was added to oxidize it to form oxidized polymer of L-DOPA (OPDOPA), which exhibits strong blue fluorescence. Based on the alkaline-catalyzed hydrolysis of MP and the inner filter effect (IFE) between its hydrolysis product p-nitrophenol (p-NP) and OPDOPA, the detection of MP was successfully achieved.Results The OPDOPA fluorescence nanoprobe presents excellent selectivity and sensitivity for MP detection. A linear response was achieved from 0.5 to 30 & micro;g/mL, and the limit of detection was determined to be 0.08 & micro;g/mL. The fluorescence detection system was utilized for the determination of MP in potato and Codonopsis pilosula samples. For the actual analysis of the two sample matrices, the sensor exhibited recovery rates spanning 92.00%-106.42% and a relative standard deviation (RSD) of <= 5.83%.Discussion In this study, a functional polymer material with excellent fluorescence properties was synthesized from L-DOPA and applied to the highly sensitive and selective detection of MP. This approach not only offers a novel strategy for the detection of organophosphorus pesticides but also substantially broadens the application horizon of functional polymer materials.