文献类型：期刊文献

英文题名：Effect of comprehensive psychosomatic promotion in hypertension patients with anxiety and depression based on community A randomized parallel controlled trial

作者：Zhang, Hailiang[1];Jiang, Xiaomei[2];Da, Haixia[2];Dai, Runjing[1];Zhao, Na[1];Pan, Weimin[3];Fan, Jingchun[1]

第一作者：张虎林;张惠玲

通信作者：Fan, JC[1];Pan, WM[2]

机构：[1]Gansu Univ Chinese Med, Sch Publ Hlth, Ctr Evidence Based Med, Lanzhou, Gansu, Peoples R China;[2]Gansu Gem Flower Hosp, Psychosomat & Sleep Med, Lanzhou, Gansu, Peoples R China;[3]Gansu Prov Ctr Dis Control & Prevent, Dept Mental Hlth, Lanzhou, Gansu, Peoples R China

第一机构：甘肃中医药大学公共卫生学院

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Sch Publ Hlth, Ctr Evidence Based Med, Lanzhou, Gansu, Peoples R China;[2]corresponding author), Gansu Prov Ctr Dis Control & Prevent, Dept Mental Hlth, Lanzhou, Gansu, Peoples R China.|[10735e9d5e7087247e71b]甘肃中医药大学公共卫生学院;[10735]甘肃中医药大学;

年份：2020

卷号：99

期号：33

起止页码：E21451

外文期刊名：MEDICINE

收录：;Scopus(收录号：2-s2.0-85090182021);WOS:【SSCI(收录号:WOS:000578793300026)，SCI-EXPANDED(收录号:WOS:000578793300026)】；

基金：This study was supported by grants from The Talent Introduction Program of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine (grant number. 2016YJRC-01), and University Innovation Capacity Improvement Project in Gansu Province, Department of Education of Gansu Province, are responsible for recruiting subjects, and collecting, analyzing, interpreting data, and writing manuscripts, and evaluating the entire trial process. Major Public Health Project of China, China CDC, is responsible for providing guidance on trial theory and designing this study.

语种：英文

外文关键词：anxiety; depression; hypertension; mindfulness; psychotherapy

摘要：Background: Mental health is closely related to the occurrence of hypertension, particularly the prognosis of hypertension patients. The role of psychotherapy in the occurrence, development, prevention, and prognosis of hypertension, remains to be clarified. Methods/design: We will conduct a prospective, double-blind, randomized, multiple-centers study. Eighty patients enrolled in this trial will be randomized at 1:1 ratio. The primary endpoint is will be the reduction of the patient psychological scale (PHQ-9) score. Secondary endpoints will be the drop in blood pressure, awareness of physical and mental health and self-efficacy scale. Measurements will be performed at baseline, 5-week (questionnaires only), 10-week (primary endpoint), using the Anxiety Screening Questionnaire (GAD-7) and Depression Scale (PHQ-9). Data analysis will be carried out using the SPSS v.25 software assuming a level of significance of 5%. Results will be analyzed using multilevel, regression analysis and hierarchical linear models. Discussion: We hope to provide some insight in the understanding the underlying mechanism of the novel mindfulness in the management of hypertension related psychological stress/disturbance, and will enable us to develop novel approach to manage essential hypertension and its related psychological disorders.