文献类型：期刊文献

中文题名：祖师麻凝胶膏剂制备工艺研究

英文题名：Optimization of Preparation Technology for Zushima Gel Cream

作者：范彬[1];石晓峰[1];蔺莉[1,2];张君菡[2];马趣环[1];沈薇[1];刘东彦[1];王新娣[1]

第一作者：范彬

机构：[1]甘肃省医学科学研究院药物研究所,甘肃兰州730050;[2]甘肃中医药大学,甘肃兰州730000

第一机构：甘肃省医学科学研究院药物研究所,甘肃兰州730050

年份：2016

卷号：23

期号：10

起止页码：104

中文期刊名：中国中医药信息杂志

外文期刊名：Chinese Journal of Information on Traditional Chinese Medicine

收录：CSTPCD;;CSCD:【CSCD_E2015_2016】；

基金：甘肃省普通中医药科研课题(GZK-2011-81、GZK-2014-19);兰州市科技计划-社会发展类(2013-3-39)

语种：中文

中文关键词：祖师麻;凝胶膏剂;制备工艺;正交试验

外文关键词：Zushima; gel cream; preparation process; orthogonal test;

摘要：目的优选祖师麻凝胶膏剂的制备工艺。方法以感官评价、初黏力、持黏力和剥离强度评分的综合评分为考察指标,以搅拌时间、炼合温度、搅拌速度、药粉加入顺序为考察因素,采用正交试验进行成型工艺优选。结果祖师麻凝胶膏剂的最佳制备工艺为:祖师麻药粉加入聚丙烯酸钠NP-700和甘油中,搅拌时间为5 min、炼合温度为40℃、搅拌速度为100 r/min。结论优选工艺制备的祖师麻凝胶膏剂持粘力、光泽性、赋型性均较好,制备工艺良好。
Objective To optimize preparation process of Zushima Gel Cream. Methods The comprehensive evaluation set sensory evaluation, initial adhesive force, viscous force, and peeling strength score as indexes. The mixing time, refining temperature, mixing speed, and powder adding sequence were investigation factors. Orthogonal experiment was used to optimize forming process. Results Conditions of optimized preparation process were as following： add Zushima powder in Viscomate NP-700 and glycerol; mixing time was 5 min; refining temperature was 40 ℃; mixing speed was 100 r/min. Conclusion The preparation process is good and optimized Zushima Gel Cream has a good adhesive force, good glossiness and excipients. The preparation process is good.