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苦楝皮化学成分、药理活性及临床应用的研究进展    

Research progress on chemical constituents,pharmacological activities and clinical application of Melia Cortex

文献类型:期刊文献

中文题名:苦楝皮化学成分、药理活性及临床应用的研究进展

英文题名:Research progress on chemical constituents,pharmacological activities and clinical application of Melia Cortex

作者:赵豹[1];程明[1];薛雁斌[1];张君菡[1];张志红[1];潘新波[1];王亚丽[1]

第一作者:赵豹

机构:[1]甘肃中医药大学药学院、甘肃省中药质量与标准研究重点实验室,甘肃兰州730000

第一机构:甘肃中医药大学药学院(西北中藏药协同创新中心办公室)|甘肃中医药大学科研实验中心(甘肃省中医药标准化技术委员会秘书处)

年份:2023

卷号:38

期号:2

起止页码:227

中文期刊名:华西药学杂志

外文期刊名:West China Journal of Pharmaceutical Sciences

收录:CSTPCD

语种:中文

中文关键词:苦楝皮;川楝素;驱虫;杀虫;化学成分;药理活性;临床应用;研究进展

外文关键词:Meliae Cortex;Toosendanin;Deworming effect;Deinsectization;Chemical constituents;Pharmacological activities;Clinical application;Research progress

摘要:苦楝皮Melia Cortex是楝科楝属植物苦楝干燥的根皮或茎皮,药用历史悠久。苦楝皮主要含有三萜类、挥发油类、甾体类、有机酸类及黄酮类等成分,具有杀虫、抗肿瘤、抗菌、抗肉毒中毒等生物活性,临床上常用于驱虫和治疗皮肤疾病。现综述苦楝皮的化学成分、药理活性及临床应用的研究进展,为其研究和开发提供参考。
Meliae Cortex is from Melia plant of the Meliaceae family,whose dry root bark or stem bark is used as medicine.It mainly contains constituents,namely triterpenes,volatile oil,sterols,organic acids,and flavonoids,which have biological activities,such as insecticide,anti-cancer,anti-bacterium and anti-botulism.In clinical practice,it is often used in treatment of antiscolic diseases and skin diseases.This paper summarizes the chemical constituents,pharmacological activities and clinical application.

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