文献类型：期刊文献

英文题名：Effect of endoscopic therapy and drug therapy on prognosis and rebleeding in patients with esophagogastric variceal bleeding

作者：Jiang, Jing-jing[1,2];Gao, Chun[1,2];Mao, Jun-feng[3];Yang, Guo-yuan[2];Huang, Jun[1,2];Yu, Xiao-hui[1];Tan, Yong[1];Zhang, Jiu-cong[1];Zheng, Xiao-feng[4]

第一作者：Jiang, Jing-jing

通信作者：Zhang, JC[1];Zheng, XF[2]

机构：[1]Hosp 940 Joint Logist Support Force PLA, Dept Gastroenterol, 333rd Binhenan Rd, Lanzhou 730050, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China;[3]940 Hosp Joint Logist Support Forces PLA, Dept Nucl Med, Lanzhou 730050, Gansu, Peoples R China;[4]Lanzhou Univ, Dept Gastroenterol, Hosp 2, Lanzhou 730030, Gansu, Peoples R China

第一机构：Hosp 940 Joint Logist Support Force PLA, Dept Gastroenterol, 333rd Binhenan Rd, Lanzhou 730050, Gansu, Peoples R China

通信机构：[1]corresponding author), Hosp 940 Joint Logist Support Force PLA, Dept Gastroenterol, 333rd Binhenan Rd, Lanzhou 730050, Gansu, Peoples R China;[2]corresponding author), Lanzhou Univ, Dept Gastroenterol, Hosp 2, Lanzhou 730030, Gansu, Peoples R China.

年份：2024

卷号：14

期号：1

外文期刊名：SCIENTIFIC REPORTS

收录：;Scopus(收录号：2-s2.0-85188815885);WOS:【SCI-EXPANDED(收录号:WOS:001197657500029)】；

基金：This research was supported by the "The Top talent" lifting project of the Chinese People's Liberation Army Joint Logistic Support Force.

语种：英文

外文关键词：Esophagogastric variceal bleeding; Endoscopic therapy; Drug therapy; Propensity score matching

摘要：Esophagogastric variceal bleeding (EVB) is one of the common digestive system emergencies with poor prognosis and high rate of rebleeding after treatment. To explore the effects of endoscopic therapy and drug therapy on the prognosis and rebleeding of patients with EVB, and then select better treatment methods to effectively improve the prognosis. From January 2013 to December 2022, 965 patients with EVB who were hospitalized in gastroenterology Department of the 940 Hospital of Joint Logistic Support Forces of PLA were retrospectively analyzed. Patients were divided into endoscopic treatment group (ET, n = 586) and drug treatment group (DT, n = 379). Propensity score matching (PSM) analysis was performed in both groups, and the general information, efficacy and length of hospital stay were recorded. The patients were followed up for 3 months after bleeding control to determine whether rebleeding occurred. There were 286 cases in each group after PSM. Compared with DT group, ET had higher treatment success rate (P < 0.001), lower rebleeding rate (P < 0.001), lower mortality rate within 3 months, and no significant difference in total hospital stay (P > 0.05). Compared with drug therapy, endoscopic treatment of EVB has short-term efficacy advantages, and can effectively reduce the incidence of rebleeding and mortality within 3 months.