文献类型：期刊文献

英文题名：Separation and Purification of Liquiritigenin by Ultrafiltration-Solid Membrane Complexation Extraction Coupling Technology

作者：Wan, Lingjuan[1];Shi, Panqi[2];Feng, Xiaoli[1];He, Hongjie[1];Ran, Xin[1];Liu, Xiaoxia[1];Xu, Yiwen[1];Liu, Meiqing[1];Liu, Yuanyuan[1];Wei, Shuchang[1]

第一作者：Wan, Lingjuan

通信作者：Wei, SC[1]

机构：[1]Gansu Univ Tradit Chinese Med, Gansu Prov Engn Res Ctr Tradit Chinese Med Pharmac, 35 Dingxi East Rd, Lanzhou 730000, Peoples R China;[2]Tianshui Hosp Tradit Chinese Med, Formulat Ctr, 6 Jihe North Rd, Tianshui 741000, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Tradit Chinese Med, Gansu Prov Engn Res Ctr Tradit Chinese Med Pharmac, 35 Dingxi East Rd, Lanzhou 730000, Peoples R China.|[10735]甘肃中医药大学;

年份：2023

卷号：8

期号：11

外文期刊名：CHEMISTRYSELECT

收录：;Scopus(收录号：2-s2.0-85170102769);WOS:【SCI-EXPANDED(收录号:WOS:001063968400001)】；

基金：This work was supported by the National Natural Science Foundation of China (No. 82060721) and Gansu Province Innovation Project (No. 2022CXZX-740).

语种：英文

外文关键词：complex extraction; coupling technology; liquiritigenin; solid membrane; ultrafiltration

摘要：An ultrafiltration-solid membrane complexation extraction and reverse extraction method was developed for the separation and purification of liquiritigenin in licorice ultrafiltration, using ultrafiltration as the precursor technology. The effects of ultrafiltration pH, extraction time and three-phase flow rate on the single-stage extraction and reverse extraction rates of liquiritigenin in solid membrane were investigated, then the applicability of the single-stage process to the cascade solid membrane was investigated. The optimum cascade solid membrane process was obtained with ultrafiltration pH = 6, extraction time of 36 h and three-phase flow rate of ultrafiltration: extractant: reverse extractant = 188: 188: 94 mLmin(-1), under which the total transfer rate of liquiritigenin was 75.73%. The results showed that the solid membrane single-stage process was equally applicable to cascade solid membranes, and the results may provide a novel technology with high efficiency, environmentally friendly and low-cost for the separation of flavonoids in licorice.