文献类型：期刊文献

英文题名：Fatal fulminant septic shock with disseminated intravascular coagulation following percutaneous aspiration and sclerotherapy of a hepatic cyst: a case report

作者：Deng, Rong[1];Li, Yanlong[2];Chen, Jiale[1];Wang, Yexuan[1];Chai, Wenmin[1];Zuo, Danyun[1];Lan, Yingzong[1]

第一作者：Deng, Rong

通信作者：Li, YL[1]

机构：[1]Gansu Univ Chinese Med, Coll Integrated Tradit Chinese & Western Med, Lanzhou, Peoples R China;[2]Gansu Prov Hosp Tradit Chinese Med, Dept Spleen & Stomach Dis, Lanzhou, Peoples R China

第一机构：甘肃中医药大学中西医结合学院

通信机构：[1]corresponding author), Gansu Prov Hosp Tradit Chinese Med, Dept Spleen & Stomach Dis, Lanzhou, Peoples R China.

年份：2026

卷号：13

外文期刊名：FRONTIERS IN MEDICINE

收录：;Scopus(收录号：2-s2.0-105044386895);WOS:【SCI-EXPANDED(收录号:WOS:001808727600001)】；

基金：The author(s) declared that financial support was received for this work and/or its publication. The Second Batch of Longyuan Outstanding Young Talents Program (Grant No. 2022LQGR03), Document No. [2023] 11 issued by the Leading Group for Talent Work of CPC Gansu Provincial Committee National Natural Science Foundation of China Project (82560887) Scientific Research Project of Gansu Provincial Health Commission (GSWSONPY2024-04).

语种：英文

外文关键词：disseminated intravascular coagulation; Escherichia coli; liver cyst aspiration; percutaneous aspiration; septic shock

摘要：Liver cysts are common benign lesions. Although percutaneous aspiration combined with sclerotherapy is a safe and effective treatment, severe infectious complications are rare but potentially fatal. This report describes a rare case of a 69-year-old female patient who underwent percutaneous aspiration and polidocanol sclerotherapy for multiple liver cysts. Postoperatively, she rapidly developed fulminant septic shock complicated by disseminated intravascular coagulation (DIC), ultimately resulting in death. Laboratory tests following onset of symptoms revealed significantly elevated inflammatory markers and coagulation disorders. Despite aggressive treatment with broad-spectrum antibiotics, fluid resuscitation, vasoactive agents, anticoagulation therapy, and continuous renal replacement therapy, the patient died within 24 h of the onset of shock. Escherichia coli was detected in both blood and cyst fluid cultures, suggesting a combined pathogenic mechanism involving both percutaneous puncture-related dissemination and biliary-intestinal bacterial translocation. This case demonstrates that percutaneous interventional treatment of liver cysts may lead to complications of fulminant infection, underscoring the critical importance of early recognition and timely intervention.