文献类型：期刊文献

中文题名：萨滞布病(脑中风)的藏医病因病机及干预策略研究

英文题名：Pathogenesis and Intervention Strategies of the Tibetan Medicine for gZav-Grib Disease(Cerebral Stroke)

作者：贡保东知[1];阿达[1];完么才让[2];加羊加措[1];邱建智[1];张艺[3,4]

第一作者：贡保东知

机构：[1]甘肃中医药大学藏医学院,甘南747000;[2]甘肃中医药大学中医临床学院,兰州730000;[3]成都中医药大学民族医药学术传承创新研究中心,成都611137;[4]成都中医药大学民族医药学院,成都611137

第一机构：甘肃中医药大学藏医学院

年份：2021

卷号：16

期号：15

起止页码：2250

中文期刊名：世界中医药

外文期刊名：World Chinese Medicine

收录：CSTPCD

基金：国家重点研发计划项目(2017YFC1703904);甘肃省中医药研究中心开放课题(ZYZX-2020-ZX29);甘肃省高等学校创新能力提升项目(2020A-076);甘肃省高等学校创新能力提升项目(2021B-162)。

语种：中文

中文关键词：藏医;萨滞布病;脑中风;病因病机;研究策略;肠道菌群;代谢组学;味性化味

外文关键词：Tibetan medicine;gZav-Grib disease;Cerebral Stroke;Aetiopathogenesis;Research strategy;Intestinal flora;Metabonomics;“Ro-nus-zhu-rjes”

摘要：萨滞布病是临床常见病和多发病,藏医药治疗萨滞布病临床疗效显著,但其病因病机尚存在异议,为促进和提高萨滞布病因病机的认识,本研究查阅和古籍文献,发现萨滞布病是人体三因失去平衡后隆血紊乱,人体坏血增多,坏血在隆的反作用下黏性增高,出现血液堵塞或溢出现象,导致白脉和黑脉受损,进而引起偏瘫、失语等症状,同时依据文献将萨滞布病的证型分类进行总结和梳理。依据藏医理论和国内外萨滞布病前沿相关文献,提出了从神经血管单元、时间药理学、代谢组学、肠道菌群等方法藏药干预萨滞布病的策略,为新方法和新思路研究藏药干预萨滞布病提供了藏医理论衔接点。
gZav-Grib disease is a common and multimorbidity disease,the clinical efficacy of Tibetan medicine for the treatment of gZav-Grib disease is significant by still controversial.In order to promote and improve the understanding of the etiological mechanisms of human diseases,we reviewed ancient literature and found that gZav-Grib disease is a disorder of human blood proliferation after the loss of balance,increased human blood loss,and increased blood viscosity with the opposing effects of brodifacoum.The phenomenon of blood clogging or spillover occurs,which leads to damage to the white and black veins and then causes symptoms such as hemiplegia and aphasia,while the syndromic classification of gZav-Grib disease is summarized and combed according to the literature.Based on the theory of Tibetan medicine and relevant literature from inside and outside China on the frontiers of Tibetan medicine,the strategy of Tibetan medicine to intervene in gZav-Grib disease from neurovascular unit,chronopharmacology,metabolomics,and intestinal flora has been proposed,which may provide an adaptor point for the theory of Tibetan medicine to intervene in gZav-Grib disease by new methods and ideas.