文献类型：期刊文献

英文题名：Risk factors of ectopic pregnancy after in vitro fertilization-embryo transfer in Chinese population: A meta-analysis

作者：Wang, Yanbo[1];Chen, Li[1];Tao, Yuan[1];Luo, Mengqian[1];Stabile, Guglielmo

第一作者：王艳波

通信作者：Wang, YB[1]

机构：[1]Gansu Univ Chinese Med, Sch Nursing, Lanzhou, Gansu, Peoples R China

第一机构：甘肃中医药大学护理学院

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Sch Nursing, Lanzhou, Gansu, Peoples R China.|[107352f23a9081f8152fc]甘肃中医药大学护理学院;[10735]甘肃中医药大学;

年份：2024

卷号：19

期号：1

外文期刊名：PLOS ONE

收录：;Scopus(收录号：2-s2.0-85181670020);WOS:【SCI-EXPANDED(收录号:WOS:001136266700178)】；

基金：This study was supported by Education Technology Innovation Project in Gansu Province (No:2022A-069). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

语种：英文

摘要：BackgroundThe prevalence of ectopic pregnancy after assisted reproduction is notably high, posing a significant threat to the life safety of pregnant women. Discrepancies in published results and the lack of a comprehensive description of all risk factors have led to ongoing uncertainties concerning ectopic pregnancy after assisted reproduction.ObjectiveThis study aimed to understand the risk factors for ectopic pregnancy after in vitro fertilization-embryo transfer in the Chinese population and provide a reference for targeted prevention and treatment.MethodsA comprehensive search of the China National Knowledge Infrastructure, Wang fang Database, China Science Technology Journal Database, Chinese Biomedical Literature Database, PubMed, Web of Science, and Embase was conducted to identify relevant literature on the risk factors for ectopic pregnancy in Chinese women after assisted reproductive technology in Chinese women. A meta-analysis of the included studies was performed using Stata17.ResultsOverall, 34 articles were included in the analysis. The risk factors for ectopic pregnancy after in vitro fertilization-embryo transfer in the Chinese population included a thin endometrium on the day of HCG administration and embryo transplantation, a history of ectopic pregnancy, secondary infertility, a history of induced abortion, polycystic ovary syndrome, decreased ovarian reserve, tubal factor infertility, cleavage stage embryo transfer, fresh embryo transfer, artificial cycle protocols, elevated estradiol levels on the day of human chorionic gonadotropin administration, a history of tubal surgery, two or more number of embryo transfers, previous pregnancy history, and a history of pelvic surgery.ConclusionThis study clarified the factors influencing ectopic pregnancy after in vitro fertilization and embryo transfer in the Chinese population, focusing on high-risk groups. Targeted and personalized intervention measures should be adopted to prevent and detect the disease early to reduce its incidence and harm.Trial registrationThe protocol for this view was registered in PROSPERO (CRD42023414710).