文献类型：期刊文献

英文题名：Biclonal lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia associated with POEMS syndrome: A case report and literature review

作者：Wang, Qiulan[1];Liu, Qingbo[1];Liang, Haonan[1];Gao, Wenbin[1]

第一作者：王秋兰

通信作者：Wang, QL[1]

机构：[1]Gansu Univ Chinese Med, Coll Clin Med 1, Lanzhou 730000, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Coll Clin Med 1, Lanzhou 730000, Gansu, Peoples R China.|[10735]甘肃中医药大学;

年份：2023

卷号：25

期号：3

外文期刊名：ONCOLOGY LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000944295200001)】；

语种：英文

外文关键词：lymphoplasmacytic lymphoma; Waldenstrom macroglobulinemia; biclonal immunoglobulinemia; POEMS syndrome; IgG and IgM; rituximab

摘要：Due to its unique clinical, immunological and molecular genetic characteristics, biclonal lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia (LPL/WM) with polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes (POEMS) syndrome is extremely rare in clinical practice, and there is no standard treatment for patients afflicted with this condition. In the present case report, a rare case of double LPL/WM with POEMS syndrome is described. The patient, a 65-year-old male, exhibited significant renal impairment and polylymphadenopathy. The patient was treated with rituximab and his symptoms were resolved following two courses of treatment. A review of the literature was performed, comparing the present case with previous cases. It is hoped that this case report will enable clinicians to gain a better understanding of this disease.