文献类型：期刊文献

英文题名：Inhibitory effects of Portulaca oleracea L. and selected flavonoid ingredients on heterocyclic amines in roast beef patties and Density Function Theory calculation of binding between heterocyclic amines intermediates and flavonoids

作者：Jing, Jing[1,2]; He, Yonghui[3]; Wang, Yali[4]; Zeng, Maomao[5]

第一作者：Jing, Jing

通信作者：Zeng, Maomao

机构：[1] State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, 999078, China; [2] School of Pharmacy, Zunyi Medical University, Zunyi, 563000, China; [3] Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Nationalities University, Kunming, 650500, China; [4] Key Laboratory of Traditional Chinese Medicine Quality and Standard, Gansu University of Chinese Medicine, Lanzhou, 730101, China; [5] State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, China

第一机构：State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, 999078, China

通信机构：[5]State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, China

年份：2021

卷号：336

外文期刊名：Food Chemistry

收录：EI(收录号：20203309043395);Scopus(收录号：2-s2.0-85089231829)

语种：英文

外文关键词：Amines - Beef - Density functional theory - Calcination

摘要：The inhibitory effects of Portulaca oleracea L. (PO) and its flavonoid ingredients on the formation of heterocyclic amines (HAs) in roast beef patties were investigated. Ten HAs were found in control patties, and the total content was 212.73 ± 7.13 ng/g. With the addition of PO (1%, 5%, and 10%, w/w), HAs decreased by 62.39%, 68.03%, and 73.75%, respectively. The main flavonoid ingredients (rutin, hesperidin, and flavanone) also present a similar inhibitory effect. The Density Function Theory (DFT) methods were adopted to investigate the inhibitory mechanism. These ingredients bonded with the intermediate to block the formation of norharman. Both experimental and calculated data of the ingredients were analyzed on their HAs inhibitory capacity. Our results provide a novel and valuable strategy to reduce HAs via a low additive level of medicinal and edible plants. And the correlation between experimental and calculated data could be applied to predict the inhibitory ability of inhibitors. ? 2020 Elsevier Ltd