文献类型：期刊文献

中文题名：基于熵权TOPSIS模型对不同加工方式黄芪药材质量的综合评价

英文题名：Comprehensive Quality Evaluation of Astragali Radix Processed by Different Methods Based on Entropy Weight TOPSIS Model

作者：吴红伟[1,2];李东辉[1,2];张育贵[1,2];张淑娟[1,2];司昕蕾[1,2];边甜甜[1,2];李越峰[1,2]

第一作者：吴红伟

机构：[1]甘肃中医药大学,兰州730000;[2]甘肃省中药质量与标准研究重点实验室,兰州730000

第一机构：甘肃中医药大学

年份：2021

卷号：56

期号：16

起止页码：1325

中文期刊名：中国药学杂志

外文期刊名：Chinese Pharmaceutical Journal

收录：CSTPCD;;Scopus;北大核心:【北大核心2020】；CSCD:【CSCD2021_2022】；PubMed;

基金：国家自然科学基金项目资助(81960713);甘肃省自然科学基金创新基地和人才计划项目资助(18JR3RA197);甘肃省中药质量与标准研究重点实验室开放基金资助(ZYZL18008);甘肃中医药大学研究生创新基金项目资助(2021CX41)。

语种：中文

中文关键词：黄芪;熵权TOPSIS模型;产地加工;发汗;揉搓;质量评价

外文关键词：Astragali Radix;technique for order preference by similarity to ideal solution;diaphoretic time;kneadin;quality evaluation

摘要：目的采用熵权TOPSIS法(technique for order preference by similarity to ideal solution),评价不同产地加工方式对黄芪药材质量的影响,为黄芪药材产地加工工艺提供指导。方法通过趁鲜切制、晾晒至不同含水量(60%、50%、40%、30%、20%)、不同“发汗”时长(发汗0、1、2、3、4 d)、不同“揉搓”次数(揉搓0、1、2、3、4次)、切制及干燥等加工方式对黄芪药材进行产地加工,得到黄芪饮片。以黄芪甲苷、毛蕊异黄酮葡萄糖苷、芒柄花苷、毛蕊异黄酮、总黄酮、总多糖及水溶性浸出物为考察指标,通过熵权TOPSIS法对所得指标成分数据进行分析,优选出黄芪药材最佳产地加工工艺。结果不同产地加工方法对黄芪药材指标性成分含量具有一定影响。其中,最佳含水量为50%,发汗最佳时长为2d,揉搓最佳次数为2次。结论黄芪药材最佳产地加工工艺为:含水量为50%,发汗2d,揉搓2次。
OBJECTIVE To evaluate the influence of different processing methods on the quality of Astragali Radix by using the entropy weight technique for order preference by similarity to ideal solution(TOPSIS)method,and provide guidance for the processing methods of Astragali Radix in the origin.METHODS The origin processing of Astragali Radix was conducted by fresh-cutting,dr-ying to different water contents(60%,50%,40%,30%,20%),different"diaphoretic"days(diaphoretic 0,1,2,3,4 d),differ-ent"kneading"times(kneading 0,1,2,3,4 times),cutting,drying,etc.to obtain Astragali Radix decoction pieces.With astragalosideⅣ,campanulin,ononin,calycosin,total flavonoids,total polysaccharides and water-soluble extracts as the investigation indexes,and the component data of the obtained indexes were analyzed by entropy weight TOPSIS method,to optimize the processing technology for Astragali Radix from the optimal origin.RESULTS The processing methods from different origins had certain influence on the con-tent of index components of Astragali Radix.Among them,the optimal water content was 50%,the optimal duration of diaphoretic days was 2 d,and the optimal number of kneading times was two.CONCLUSION The optimal processing technology of Astragali Radix from the origin was as follows;water content 50%,sweating for 2 d,and kneading twice.