详细信息
文献类型:期刊文献
中文题名:黄芪的抗肿瘤作用
英文题名:Anti-tumor effect of Radix astragali
作者:吕玲[1];张立[2];李能莲[2];舍雅莉[2];黄勇[2];程小丽[2];刘青[1]
第一作者:吕玲
机构:[1]甘肃省妇幼保健院,兰州730000;[2]甘肃中医学院,兰州730000
第一机构:甘肃省妇幼保健院,兰州730000
年份:2014
卷号:35
期号:5
起止页码:I0004
中文期刊名:世界临床药物
外文期刊名:World Clinical Drug
收录:CSTPCD
基金:甘肃省中医药管理局课题(GZK-2013-56)
语种:中文
中文关键词:黄芪;抗肿瘤;药理作用
外文关键词:Radix astragali; anti-tumor; pharmacological effect
摘要:黄芪化学成分主要有黄芪多糖、皂苷类及黄酮类等。体内外药理实验显示,其抗肿瘤作用明显。本文综述其在增强免疫调节作用、诱导细胞凋亡、提高机体清除自由基的能力、抑制肿瘤的血管系统,以及减轻肿瘤化疗药物不良反应等方面的抗肿瘤作用机制研究进展。
The main chemical ingredients of Radix astragali are astragalus polysaccharide, saponins and flavonoid. Both in vivo and in vitro pharmacological experiment indicated that Radix astragali has an obvious anti-tumor effect. This review focuses on the mechanism probably in the enhancement of the immune regulating function, inducting of apoptosis, improving the organism's ability of eliminating free radicals, suppressing the tumor blood system and alleviating the adverse reactions of tumor chemotherapy drugs.
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