文献类型：期刊文献

中文题名：中药保留灌肠联合盐酸坦索罗辛缓释胶囊治疗慢性非细菌性前列腺炎/慢性骨盆疼痛综合征临床研究

英文题名：Clinical Observation on Traditional Chinese Medicine Retention-enema Combined with Tamsulsosin Hydrochloride Capsules in Treating Chronic Abacterial Prostatitis/Chronic Pelvic Pain Syndrome

作者：王新平[1];易剑锋[2];严兴科[3];赵春霖[1];潘海邦[2];董小鹏[2]

第一作者：王新平

机构：[1]甘肃中医学院附属医院外科;[2]甘肃中医学院临床学院;[3]甘肃中医学院针灸学院

第一机构：甘肃中医药大学第二附属医院

年份：2014

卷号：21

期号：3

起止页码：18

中文期刊名：中国中医药信息杂志

外文期刊名：Chinese Journal of Information on Traditional Chinese Medicine

收录：CSTPCD;;CSCD:【CSCD_E2013_2014】；

基金：国家自然科学基金(81060304)

语种：中文

中文关键词：盐酸坦索罗辛缓释胶囊;慢性非细菌性前列腺炎;慢性骨盆疼痛综合征;中药保留灌肠

外文关键词：tamsulsosin hydrochloride capsules;chronic abacterial prostatitis/chronic pelvic pain syndrome;traditional Chinese medicine retention-enema

摘要：目的探讨中药保留灌肠联合盐酸坦索罗辛缓释胶囊治疗慢性非细菌性前列腺炎/慢性骨盆疼痛综合(CABP/CPPS)的临床疗效。方法选择甘肃中医学院附属医院2007年9月-2012年10月CABP/CPPS患者200例,按就诊先后次序随机分为对照组、观察组,每组100例。对照组给予盐酸坦索罗辛缓释胶囊,每次0.2 mg,睡前口服;观察组在对照组治疗基础上,联合中药保留灌肠。2组均治疗4周。观察2组疗效及治疗前后慢性前列腺炎症状评分(NIH-CPSI)、前列腺液白细胞计数、卵磷脂小体、尿流率变化。结果观察组总有效率为100%(100/100),对照组88%(88/100),2组比较差异有统计学意义(P<0.05);治疗后观察组前列腺液白细胞计数和NIH-CPSI评分明显低于对照组,差异有统计学意义(P<0.05);治疗后观察组卵磷脂小体(++++)者明显多于对照组,差异有统计学意义(P<0.05);治疗后2组尿流率均增加,组间比较差异无统计学意义(P>0.05)。结论中药保留灌肠联合盐酸坦索罗辛缓释胶囊可显著提高CABP/CPPS的临床疗效。
Objective To investigate the effect of traditional Chinese medicine retention-enema combined with tamsulsosin hydrochloride capsules in treating chronic abacterial prostatitis/chronic pelvic pain syndrome. Methods Two hundred patients of CABP/CPPS from Affiliated Hospital of Gansu University of TCM during September 2007-October 2012 were randomly divided into control group and observation group, 100 cases in each group. The control group received the treatment of tamsulsosin hydrochloride capsules, 0.2 mg/d, qn, and the observation group received the treatment of traditional Chinese medicine retention-enema additionally. The course was 4 weeks. The clinical effects of the two groups were observed and compared. The indexes including the scores of NIH-CPSI, leukocyte count and lecithin corpuscles in prostatic fluid, urinary flow rate were evaluated. Results The total effective rate was 100%（100/100） in observation group, and 88% （88/100） in control group. There was significant difference between the two groups （P〈0.05）. The scores of NIH-CPSI and leukocyte count in observation group were significantly lower than those in control group after treatment, with significant difference （P〈0.05）. The cases with lecithin corpuscles （＋＋＋＋） in observation group were more than those in control group （P〈0.05）. The peak flow rate and mean flow rate increased after treatment in both groups, and there was no statistically difference between the two groups （P＆gt;0.05）. Conclusion Traditional Chinese medicine retention-enema combined with tamsulsosin hydrochloride capsules can significantly improve the clinical effect of CABP/CPPS.