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成果/Result
- 1Natural diterpenoid eriocalyxin B covalently modifies glutathione and selectively inhibits thioredoxin reductase inducing potent oxidative stress-mediated apoptosis in colorectal carcinoma RKO cells被引量：10收藏
- 作者：Duan, Dongzhu Wang, Yanru Jin, Xiaojie Li, Mi Wang, Le
- 机构：Baoji Univ Arts & Sci;Baoji Univ Arts & Sci;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：FREE RADICAL BIOLOGY AND MEDICINE 2021年177卷
- JCR：一分区
- 影响因子：8.101
- 关键词：Thioredoxin reductase Eriocalyxin B Colorectal cancer Redox homeostasis Oxidative stress Apoptosis
- 2Tumor killing by a dietary curcumin mono-carbonyl analog that works as a selective ROS generator via TrxR inhibition被引量：7收藏
- 作者：Liu, Xuefeng Cui, Hongmei Li, Mi Chai, Zuohu Wang, Haibo
- 机构：Lanzhou Univ;Lanzhou Univ;Lanzhou Univ;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2023年250卷
- JCR：一分区
- 影响因子：6
- 关键词：Anticancer Curcumin Thioredoxin reductase Reactive oxygen species Apoptosis Ferroptosis
- 3Structure-Based Discovery of the SARS-CoV-2 Main Protease Noncovalent Inhibitors from Traditional Chinese Medicine被引量：4收藏
- 作者：Jin, Xiaojie Zhang, Min Fu, Beibei Li, Mi Yang, Jingyi
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chongqing Univ;Chongqing Univ
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2024年64卷4期
- JCR：一分区
- 影响因子：6.162
- 关键词：Binding energy - Diseases - Ions - Lead compounds - Molecular dynamics - Scaffolds
- 4Deciphering the active constituents of dabushen decoction of ameliorating osteoarthritis via PPARγ preservation by targeting DNMT1被引量：3收藏
- 作者：Qiu, Lu Zhang, Min Li, Chenghao Hou, Yehu Liu, Hao
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Baoji Univ Arts & Sci;Baoji Univ Arts & Sci
- 来源：FRONTIERS IN PHARMACOLOGY 2022年13卷
- JCR：一分区
- 影响因子：5.6
- 关键词：traditional Chinese medicine dabushen decoction osteoarthritis epigenetics Dnmt1 PPAR gamma
- 5Guiqi Baizhu prescription ameliorates cytarabine-induced intestinal mucositis by targeting JAK2 to inhibit M1 macrophage polarization被引量：3收藏
- 作者：Chu, Wei Li, Ya-ling Li, Jun-jie Lin, Jia Li, Mi
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;First Hosp Lanzhou Univ
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2023年164卷
- JCR：一分区
- 影响因子：6.9
- 关键词：Intestinal mucositis JAK2 STAT1 Macrophage polarization Acridine Senkyunolide A
- 6Br?nsted Acid-Catalyzed Intramolecular Tandem Double Cyclization of γ-Hydroxy Acetylenic Ketones with Alkynes into Naphtho[1,2-b]furan-3-ones被引量：1收藏
- 作者：Zhang, Sen Zhu, Hai-Tao Xi, Jia-Jun Wang, San-Bao Chang, Xin
- 机构：Baoji Univ Arts & Sci;Gansu Univ Chinese Med;Shangrao Normal Univ
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2024年89卷3期
- JCR：一分区
- 影响因子：4.198
- 7Targeting thioredoxin reductase by eupalinilide B promotes apoptosis of colorectal cancer cells in vitro and in vivo被引量：0收藏
- 作者：Duan, Dongzhu Guo, Xiangyu Tian, Jingjing Li, Mi Jin, Xiaojie
- 机构：Baoji Univ Arts & Sci;Fujian Med Univ;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：CHEMICO-BIOLOGICAL INTERACTIONS 2024年399卷
- JCR：一分区
- 影响因子：5.168
- 关键词：Thioredoxin reductase Eupalinilides B Colorectal cancer Oxidative stress Apoptosis
