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- 1Protective effect of astragalus membranaceus and its bioactive compounds against the intestinal inflammation in Drosophila被引量：26收藏
- 作者：He, Jianzheng Li, Xu Yang, Shipei Shi, Yan Dai, Yuting
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：FRONTIERS IN PHARMACOLOGY 2022年13卷
- JCR：一分区
- 影响因子：5.6
- 关键词：inflammatory bowel disease Astragalus membranaceus intestinal homeostasis bioactive compounds Drosophila melanogaster
- 2Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease被引量：21收藏
- 作者：Xiu, Minghui Wang, Yixuan Yang, Dan Zhang, Xueyan Dai, Yuting
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med
- 来源：FRONTIERS IN PHARMACOLOGY 2022年13卷
- JCR：一分区
- 影响因子：5.6
- 关键词：inflammatory bowel disease Drosophila melanogaster natural products drug discovery molecular pathways
- 3Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease被引量：20收藏
- 作者：Li, Botong Wang, Yixuan Jiang, Xiaolin Du, Hongwei Shi, Yan
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Polit Sci & Law
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2023年164卷
- JCR：一分区
- 影响因子：6.9
- 关键词：Nrf2 ARE signaling pathway Inflammatory bowel disease Nature compounds Natural extract Compound recipe Gut microbe
- 4Irinotecan cause the side effects on development and adult physiology, and induces intestinal damage via innate immune response and oxidative damage in Drosophila被引量：5收藏
- 作者：He, Jianzheng Han, Shuzhen Wang, Yixuan Kang, Qian Wang, Xiaoqian
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Prov Hosp;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2023年169卷
- JCR：一分区
- 影响因子：6.9
- 关键词：Chemotherapy Irinotecan Side effects Drosophila melanogaster Intestine
- 5The protective effect and bioactive compounds of Astragalus membranaceus against neurodegenerative disorders via alleviating oxidative stress in Drosophila被引量：4收藏
- 作者：Dai, Yuting Wang, Yixuan Kang, Qian Wu, Yifan Liu, Yongqi
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ
- 来源：FASEB JOURNAL 2024年38卷13期
- JCR：一分区
- 影响因子：5.834
- 关键词：antioxidant Astragalus membranaceus bioactive compounds Drosophila melanogaster neurodegenerative diseases
- 6基于Th17/Treg平衡探讨甲氨蝶呤对类风湿性关节炎骨保护作用的研究进展被引量：0收藏
- 作者：王渊学 王丹丹 魏锦慧 王涛
- 机构：甘肃中医药大学附属医院药学部;甘肃中医药大学附属医院脾胃病科;甘肃中医药大学附属医院肾病科;甘肃中医药大学附属医院风湿骨病一科
- 来源：《临床合理用药》 2025年18卷19期
- 关键词：类风湿性关节炎 甲氨蝶呤 Th17/Treg平衡 骨保护 免疫调节
- 摘要：类风湿性关节炎的骨破坏与辅助性T细胞17/调节性T细胞(Th17/Treg)失衡密切相关,Th17通过分泌白介素-17等促炎因子驱动破骨细胞活化,而Treg功能缺陷则加剧免疫稳态失调。甲氨蝶呤作为治疗类风湿性关节炎的一线...
- 7Therapeutic potential of Astragalus membranaceus-Pueraria lobata decoction for the treatment of chemotherapy bowel injury被引量：0收藏
- 作者：Wang, Yixuan Qin, Yujie Kang, Qian Wang, Huinan Zhou, Shihong
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Second Prov Peoples Hosp Gansu
- 来源：FASEB JOURNAL 2024年38卷19期
- JCR：一分区
- 影响因子：5.834
- 关键词：Astragalus membranaceus chemotherapy Drosophila melanogaster intestinal mucositis molecular mechanism Pueraria lobata decoction
