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成果/Result
- 1A polysaccharide-based micelle-hydrogel synergistic therapy system for diabetes and vascular diabetes complications treatment被引量：37收藏
- 作者：Wen, Na Lu, Shaoyu Xu, Xiubin Ning, Piao Wang, Zengqiang
- 机构：Lanzhou Univ;Guangzhou Univ;Gansu Univ Tradit Chinese Med;Lanzhou City Univ
- 来源：MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 2019年100卷
- JCR：一分区
- 影响因子：8.457
- 关键词：Micelle Hydrogel Glucose-responsive Synergistic therapy Thrombolysis
- 2A rapid and specific fluorescent probe based on aggregation-induced emission enhancement for mercury ion detection in living systems被引量：19收藏
- 作者：An, Yong Li, Bo Yu, Yongzhi Zhou, Yucen Yi, Jianfeng
- 机构：Gansu Univ Chinese Med;Gansu Univ Key Lab Mol Med & Chinese Med Prevent &;Gansu Univ Chinese Med;Gansu Prov Canc Hosp;China West Normal Univ
- 来源：JOURNAL OF HAZARDOUS MATERIALS 2024年465卷
- JCR：一分区
- 影响因子：12.2
- 关键词：Aggregation-induced emission Mercury ions Peptide Oxidative stress Biomimetic probe
- 3Isorhamnetin Promotes MKN-45 Gastric Cancer Cell Apoptosis by Inhibiting PI3K-Mediated Adaptive Autophagy in a Hypoxic Environment被引量：19收藏
- 作者：Li, Chenghao Li, Jiawei Li, Yan Li, Ling Luo, Yali
- 机构：Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2021年69卷29期
- JCR：一分区
- 影响因子：5.895
- 关键词：isorhamnetin apoptosis autophagy PI3K gastric cancer
- 4Osthole ameliorates simulated microgravity-induced bone loss through down-regulation of miR-34c-5p被引量：5收藏
- 作者：Feng, Xiu Zhou, Heng Zhang, Yanan Yang, Pengfei Bai, Hao
- 机构：Chinese Acad Sci;Chinese Acad Sci;Univ Chinese Acad Sci;Gansu Univ Tradit Chinese Med;Lanzhou Univ
- 来源：ACTA ASTRONAUTICA 2021年183卷
- JCR：一分区
- 影响因子：2.954
- 关键词：Osthole miR-34c-5p Simulated microgravity Bone loss
- 5Structure-Based Discovery of the SARS-CoV-2 Main Protease Noncovalent Inhibitors from Traditional Chinese Medicine被引量：4收藏
- 作者：Jin, Xiaojie Zhang, Min Fu, Beibei Li, Mi Yang, Jingyi
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chongqing Univ;Chongqing Univ
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2024年64卷4期
- JCR：一分区
- 影响因子：6.162
- 关键词：Binding energy - Diseases - Ions - Lead compounds - Molecular dynamics - Scaffolds
- 6The antioxidant effects of hedysarum polybotrys polysaccharide in extending lifespan and ameliorating aging-related diseases in Drosophila melanogaster被引量：3收藏
- 作者：Yang, Shipei Xiu, Minghui Li, Xu Shi, Yan Wang, Shuwei
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023年241卷
- JCR：一分区
- 影响因子：7.7
- 关键词：Hedysarum polybotrys polysaccharide Anti-aging Intestinal homeostasis Sleep disturbances AlzhEImer's disease Drosophila melanogaster
- 7Angelica sinensis polysaccharide extends lifespan and ameliorates aging-related diseases via insulin and TOR signaling pathways, and antioxidant ability in Drosophila被引量：0收藏
- 作者：Tuo, Wenjuan Wang, Shuwei Shi, Yan Cao, Wangjie Liu, Yongqi
- 机构： Provincial-level Key Laboratory for Molecular Medicine of Major Diseases and The Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and University; College of Basic Medicine; College of Public Health; Key Laboratory of Dunhuang Medicine
- 来源：International Journal of Biological Macromolecules 2023年241卷
- JCR：一分区
- 影响因子：8.025
- 关键词：Cell proliferation - Cell signaling - Insulin - Neurodegenerative diseases - Sleep research - Stem cells
- 8Systematic Insight into the Dual Inhibitory Mechanism of Duhuo Jisheng Decoction Targeting Cox-2 and 5-Lox Against Osteoarthritis Based on in Silico and Bioassay Methods被引量：0收藏
- 作者：Zhang, Min Li, Yaling Liu, Hao Hao, Guoxiong Zhang, Huijuan
- 机构： College of Pharmacy; Gansu University; Key Laboratory of Dunhuang Medicine; Clinical College of Traditional Chinese Medicine; Medical College
- 来源：SSRN 2024年
- 关键词：Binding energy - Diagnosis - Enzyme inhibition - Flavonoids - Free energy - Plants (botany)
- 9Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster被引量：0收藏
- 作者：Li, Xu Yang, Shipei Wang, Shuwei Shi, Yan Dai, Yuting
- 机构： College of Public Health; Provincial-level Key Laboratory for Molecular Medicine of Major Diseases and The Prevention and Treatment with Traditional Chinese Medicine Research in Gansu Colleges and University; College of Basic Medicine; Key Laboratory for Transfer of Dunhuang Medicine at the Provincial and Ministerial Level; Institute of Infection
- 来源：International Journal of Biological Macromolecules 2023年234卷
- JCR：一分区
- 影响因子：8.025
- 关键词：Neurodegenerative diseases - Signaling - Sleep research
- 10Gastrodin extends the lifespan and protects against neurodegeneration in the: Drosophila PINK1 model of Parkinson's disease被引量：0收藏
- 作者：He, Jianzheng Li, Xu Yang, Shipei Li, Yaling Lin, Xingyao
- 机构： Provincial-Level Key Laboratory for Molecular Medicine of Major Diseases; College of Basic Medicine; College of Public Health; Key Laboratory for Transfer of Dunhuang Medicine at the Provincial and Ministerial Level; College of Chemistry and Chemical Engineering
- 来源：Food and Function 2021年12卷17期
- JCR：一分区
- 影响因子：6.317
- 关键词：Antioxidants - Neurons - Amines - Neurodegenerative diseases - Brain
