甘肃中医药大学机构知识库

成果/Result

1Isolation, Identification, and Activity Evaluation of Chemical Constituents from Soil Fungus Fusarium avenaceum SF-1502 and Endophytic Fungus Fusarium proliferatum AF-04被引量：39收藏 分享

作者：Jiang, Chun-Xiao Li, Jie Zhang, Jun-Min Jin, Xiao-Jie Yu, Bo

机构：Lanzhou Univ;Lanzhou Univ;Gansu Univ Chinese Med;Taizhou Univ

来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY  2019年67卷7期

JCR：一分区

影响因子：4.192

关键词：Fusarium avenaceum SF-1502   Fusarium proliferatum AF-04   naphthoisoxazole amide   alkaloid   sesquiterpenoid   1,4-naphthoquinone   depsipeptide   antibacterial activity  

2Using Immune-Related lncRNA Signature for Prognosis and Response to Immunotherapy in Cutaneous Melanoma被引量：20收藏 分享

作者：Xue, Ling Wu, Pingfan Zhao, Xiaowen Jin, Xiaojie Wang, Jingjing

机构：Gansu Univ Chinese Med;940th Hosp Joint Logist Support Peoples Liberat A;Gansu Univ Chinese Med

来源：INTERNATIONAL JOURNAL OF GENERAL MEDICINE  2021年14卷

JCR：三分区

影响因子：2.145

关键词：melanoma   long non-coding RNA   immune checkpoint   TCGA   GSEA  

3Explore the mechanism and substance basis of Mahuang FuziXixin Decoction for the treatment of lung cancer based on network pharmacology and molecular docking被引量：20收藏 分享

作者：Zhang, Weitong Tian, Wangqi Wang, Yifan Jin, Xiaojie Guo, Hui

机构：Shaanxi Univ Chinese Med;Gansu Univ Chinese Med;Macau Univ Sci & Technol

来源：COMPUTERS IN BIOLOGY AND MEDICINE  2022年151卷

JCR：一分区

影响因子：7.7

关键词：Lung cancer   Mahuang FuziXixin Decoction   Traditional Chinese medicine   Network pharmacology   Molecular docking  

4Isorhamnetin Promotes MKN-45 Gastric Cancer Cell Apoptosis by Inhibiting PI3K-Mediated Adaptive Autophagy in a Hypoxic Environment被引量：19收藏 分享

作者：Li, Chenghao Li, Jiawei Li, Yan Li, Ling Luo, Yali

机构：Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY  2021年69卷29期

JCR：一分区

影响因子：5.895

关键词：isorhamnetin   apoptosis   autophagy   PI3K   gastric cancer  

5(±)-Alternamgin, a Pair of Enantiomeric Polyketides, from the Endophytic Fungi Alternaria sp. MG1被引量：17收藏 分享

作者：Wu, Jun-Chen Hou, Yanan Xu, Qianhe Jin, Xiao-Jie Chen, Yaxiong

机构：Lanzhou Univ;Gansu Univ Chinese Med;Chinese Acad Sci

来源：ORGANIC LETTERS  2019年21卷5期

JCR：一分区

影响因子：6.091

6Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer被引量：16收藏 分享

作者：Li, Ling Jin, Xiao-jie Li, Jia-wei Li, Cheng-hao Zhou, Shuang-yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chongqing Univ Posts & Telecommun;Gansu Univ Chinese Med

来源：CANCER SCIENCE  2021年112卷5期

JCR：二分区

影响因子：6.518

关键词：gastric cancer   Guiqi Baizhu prescription   molecular docking   molecular dynamics simulation   MST analysis   network pharmacology  

7Labdane-Type Diterpenoids from Leonurus japonicus and Their Plant-Growth Regulatory Activity被引量：12收藏 分享

作者：Li, Hang-Ying Peng, Xing Jin, Xiaojie Wei, Wen-Jun Ma, Kai-Liang

机构：Lanzhou Univ;Gansu Univ Chinese Med

来源：JOURNAL OF NATURAL PRODUCTS  2019年82卷9期

JCR：一分区

影响因子：3.782

8Natural diterpenoid eriocalyxin B covalently modifies glutathione and selectively inhibits thioredoxin reductase inducing potent oxidative stress-mediated apoptosis in colorectal carcinoma RKO cells被引量：10收藏 分享

作者：Duan, Dongzhu Wang, Yanru Jin, Xiaojie Li, Mi Wang, Le

机构：Baoji Univ Arts & Sci;Baoji Univ Arts & Sci;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FREE RADICAL BIOLOGY AND MEDICINE  2021年177卷

JCR：一分区

影响因子：8.101

关键词：Thioredoxin reductase   Eriocalyxin B   Colorectal cancer   Redox homeostasis   Oxidative stress   Apoptosis  

9Rheumatoid arthritis drug sinomenine induces apoptosis of cervical tumor cells by targeting thioredoxin reductase in vitro and in vivo被引量：10收藏 分享

作者：Duan, Dongzhu Wang, Yanru Pan, Dabo Jin, Xiaojie Yan, Yunyun

机构：Baoji Univ Arts & Sci;Baoji Univ Arts & Sci;Fujian Med Univ;Qiandongnan Vocat & Tech Coll Nationalities;Gansu Univ Chinese Med

来源：BIOORGANIC CHEMISTRY  2022年122卷

JCR：一分区

影响因子：5.1

关键词：Sinomenine   Thioredoxin reductase   Chemotherapeutic agents   Reactive oxygen species   Oxidative stress   Apoptosis  

10Targeting thioredoxin reductase by deoxyelephantopin from Elephantopus scaber triggers cancer cell apoptosis被引量：10收藏 分享

作者：Duan, Dongzhu Wang, Yanru Pan, Dabo Wang, Le Xiao, Jian

机构：Baoji Univ Arts & Sci;Baoji Univ Arts & Sci;Qiandongnan Vocat & Tech Coll Nationalities;Gansu Univ Chinese Med;Key Lab Prevent & Treatment Chron Dis TCM

来源：ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS  2021年711卷

JCR：二分区

影响因子：4.114

关键词：Thioredoxin reductase   Deoxyelephantopin   Redox regulation   Oxidative stress   Apoptosis  

11Bellidifolin Inhibits Proliferation of A549 Cells by Regulating STAT3/COX-2 Expression and Protein Activity被引量：9收藏 分享

作者：Li Yan Luo Yali Li Chenghao Feng Caiqin Zhu Zhongbo

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ Peoples Republ China;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：JOURNAL OF ONCOLOGY  2020年2020卷

JCR：二分区

影响因子：4.375

12Deciphering the Active Compounds and Mechanisms of HSBDF for Treating ALI via Integrating Chemical Bioinformatics Analysis被引量：8收藏 分享

作者：Wang, Yanru Jin, Xiaojie Fan, Qin Li, Chenghao Zhang, Min

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chinese Acad Sci;Dalian Univ

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：Traditional Chinese medicine   Huashi Baidu formula   acute lung injury   inflammation   oxidative stress   apoptosis  

13Tumor killing by a dietary curcumin mono-carbonyl analog that works as a selective ROS generator via TrxR inhibition被引量：7收藏 分享

作者：Liu, Xuefeng Cui, Hongmei Li, Mi Chai, Zuohu Wang, Haibo

机构：Lanzhou Univ;Lanzhou Univ;Lanzhou Univ;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY  2023年250卷

JCR：一分区

影响因子：6

关键词：Anticancer   Curcumin   Thioredoxin reductase   Reactive oxygen species   Apoptosis   Ferroptosis  

14PEGylated NALC-functionalized gold nanoparticles for colorimetric discrimination of chiral tyrosine被引量：6收藏 分享

作者：Chen, Xin-Yue Ha, Wei Jin, Xiao-Jie Shi, Yan-Ping

机构：Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Chinese Med

来源：ANALYST  2020年145卷22期

JCR：一分区

影响因子：4.616

关键词：Amino acids - Color - Enantiomers - Fiber optic sensors - Gold nanoparticles - Metal nanoparticles  

15Developing dietary curcumin mono-carbonyl piperidinone analogs as Nrf2-dependent cytoprotectors against oxidative damage: Structure-activity relationship and mechanisms被引量：6收藏 分享

作者：Liu, Xue-Feng Wang, Qi Zheng, Jia-Fang Chai, Zuo-Hu Dai, Fang

机构：Lanzhou Univ;Lanzhou Univ;Gansu Univ Tradit Chinese Med

来源：FREE RADICAL BIOLOGY AND MEDICINE  2022年186卷

JCR：一分区

影响因子：7.4

关键词：Curcumin   Nrf2   Michael acceptor   Cytoprotection   Oxidative stress  

16Astragaloside IV alleviates cytarabine-induced intestinal mucositis by remodeling macrophage polarization through AKT signaling被引量：5收藏 分享

作者：Li, Jun-Jie Li, Ya-Ling Chu, Wei Li, Gao-Qin Zhang, Min

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：PHYTOMEDICINE  2023年109卷

JCR：一分区

影响因子：6.7

关键词：Cytarabine   Intestinal mucositis   Macrophage polarization   Astragaloside IV   AKT  

17Structure-Based Discovery of the SARS-CoV-2 Main Protease Noncovalent Inhibitors from Traditional Chinese Medicine被引量：4收藏 分享

作者：Jin, Xiaojie Zhang, Min Fu, Beibei Li, Mi Yang, Jingyi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chongqing Univ;Chongqing Univ

来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING  2024年64卷4期

JCR：一分区

影响因子：6.162

关键词：Binding energy - Diseases - Ions - Lead compounds - Molecular dynamics - Scaffolds  

18Enhanced dissolution of galactomannan and highly efficient selenium functionalization using ionic liquids with dual roles as solvents and catalysts被引量：4收藏 分享

作者：Jia, Xiaoyan Li, Rumei Zhu, Shuping Bao, Aijuan Liu, Xiaoxiao

机构：Northwest Normal Univ;Lanzhou Inst Food & Drug Control;Gansu Univ Chinese Med;Northwest Normal Univ

来源：CARBOHYDRATE POLYMERS  2024年323卷

JCR：一分区

影响因子：10.7

关键词：Galactomannan   Functionalized ionic liquid   Dissolution mechanism   Anion-cation synergetic   Selenized polysaccharide  

19Guiqi Baizhu prescription ameliorates cytarabine-induced intestinal mucositis by targeting JAK2 to inhibit M1 macrophage polarization被引量：3收藏 分享

作者：Chu, Wei Li, Ya-ling Li, Jun-jie Lin, Jia Li, Mi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;First Hosp Lanzhou Univ

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年164卷

JCR：一分区

影响因子：6.9

关键词：Intestinal mucositis   JAK2   STAT1   Macrophage polarization   Acridine   Senkyunolide A  

20Synthesis and Biological Evaluation of Gentiopicroside Derivatives as Novel Cyclooxygenase-2 Inhibitors with Anti-Inflammatory Activity被引量：3收藏 分享

作者：Ren, Guojin Zhang, Qili Xia, Pengfei Wang, Jie Fang, Pengxia

机构：Gansu Univ Chinese Med;Northwest Collaborat Innovat Ctr Tradit Chinese Me;Qual TCM Coll Gansu Prov;Gansu Prov Engn Lab TCM Standardizat Technol & Pop;Lanzhou Inst Food & Drug Control

来源：DRUG DESIGN DEVELOPMENT AND THERAPY  2023年17卷

JCR：二分区

影响因子：4.7

关键词：gentiopicroside derivatives   structural modification   anti-inflammatory   cyclooxygenase-2 inhibitors   molecular docking  

21Deciphering the active constituents of Dabushen decoction of ameliorating osteoarthritis via PPARγ preservation by targeting DNMT1被引量：3收藏 分享

作者：Qiu, Lu Zhang, Min Li, Chenghao Hou, Yehu Liu, Hao

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Baoji Univ Arts & Sci;Baoji Univ Arts & Sci

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：traditional Chinese medicine   Dabushen decoction   osteoarthritis   epigenetics   Dnmt1   PPAR gamma  

22Licoflavone A Suppresses Gastric Cancer Growth and Metastasis by Blocking the VEGFR-2 Signaling Pathway被引量：3收藏 分享

作者：Hongxia, Gong Xiaojie, Jin Guangxian, Leng Min, Zhang Shiwei, Niu

机构：Gansu Univ Chinese Med;Tradit Chinese Med;NHC Key Lab Diag & Therapy Gastrointestinal Tumor;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：JOURNAL OF ONCOLOGY  2022年2022卷

JCR：二分区

影响因子：4.501

23Synthesis of Se polysaccharide catalyzed by sulfonic acid functionalized ionic liquids: Synergism effect of anion/cation被引量：3收藏 分享

作者：Wei, Zhangkun Guo, Duoduo He, Jianhua Liu, Xiaoxiao Wei, Yabing

机构：Northwest Normal Univ;Lanzhou Inst Food & Drug Control;Gansu Univ Chinese Med;Northwest Normal Univ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年245卷

JCR：一分区

影响因子：7.7

关键词：Se-functionalization   Sulfonic acid functionalized ionic liquids & nbsp   catalyst   Synergism effect of anion   cation  

24Metal-Free Intramolecular [3+2] Cycloaddition of γ-Hydroxy Acetylenic Ketones with Alkynes for the Synthesis of Naphtho[1,2-c]furan-5-ones and Its Derivatization via a Selective C(sp²)-H Deuteration Reaction被引量：3收藏 分享

作者：Ning, Si-Si Meng, Dan Zhang, Jie-Yun Liu, Shi-Lei Zhou, Ni-Ni

机构：Baoji Univ Arts & Sci;Gansu Univ Chinese Med

来源：JOURNAL OF ORGANIC CHEMISTRY  2021年86卷11期

JCR：一分区

影响因子：4.198

25Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β被引量：2收藏 分享

作者：Yang, Hange Zhang, Xiaowei Wang, Cong Zhang, Hailong Yi, Juan

机构：Lanzhou Univ; Lanzhou Univ;Inst Mat Med;Gansu Univ Chinese Med;Lanzhou Univ

来源：SIGNAL TRANSDUCTION AND TARGETED THERAPY  2023年8卷1期

JCR：一分区

影响因子：40.8

26Efficacy and safety of targeted drugs in advanced or metastatic gastric and gastroesophageal junction cancer: A network meta-analysis被引量：1收藏 分享

作者：Gong, Hongxia Su, Yun Zhao, Lixia Ma, Li Zhang, Liying

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chinese Minist Educ & Gansu Prov;Gansu Univ Chinese Med;Lanzhou Univ

来源：JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS  2022年47卷4期

JCR：四分区

影响因子：2.145

关键词：gastric cancer   gastroesophageal junction cancer   network meta-analysis   targeted drugs  

27Br?nsted Acid-Catalyzed Intramolecular Tandem Double Cyclization of γ-Hydroxy Acetylenic Ketones with Alkynes into Naphtho[1,2-b]furan-3-ones被引量：1收藏 分享

作者：Zhang, Sen Zhu, Hai-Tao Xi, Jia-Jun Wang, San-Bao Chang, Xin

机构：Baoji Univ Arts & Sci;Gansu Univ Chinese Med;Shangrao Normal Univ

来源：JOURNAL OF ORGANIC CHEMISTRY  2024年89卷3期

JCR：一分区

影响因子：4.198

28Engineering piperlongumine-inspired analogs as Nrf2-dependent neuroprotectors against oxidative damage by an electrophilicity-based strategy被引量：1收藏 分享

作者：Wang, Qi Lin, Dong Liu, Xue-Feng Dai, Fang Jin, Xiao-Jie

机构：Lanzhou Univ;Gansu Univ Chinese Med

来源：FREE RADICAL BIOLOGY AND MEDICINE  2023年194卷

JCR：一分区

影响因子：7.4

关键词：Piperlongumine   Electrophilicity   Nrf2   Neuroprotection   Oxidative stress  

29Discovery of an EP300 Inhibitor using Structure-based Virtual Screening and Bioactivity Evaluation被引量：1收藏 分享

作者：Pan, Dabo Huang, Yaxuan Jiang, Dewen Zhang, Yonghao Wu, Mingkai

机构：Qiandongnan Vocat & Tech Coll Nationalities;Guizhou Med Univ;Gansu Univ Chinese Med

来源：CURRENT PHARMACEUTICAL DESIGN  2024年30卷25期

JCR：三分区

影响因子：3.31

关键词：EP300   inhibitor   structure-based virtual screening   binding free energy calculation   molecular dynamics simulations   disease  

30Dual Proton/Silver-Catalyzed Serial (5+2)-Cycloaddition and Nazarov Cyclization of (E)-2-Arylidene-3-hydroxyindanones with Conjugated Eneynes: Synthesis of Indanone-Fused Benzo[cd]azulenes被引量：1收藏 分享

作者：Zhu, Hai-Tao Liang, Chun-Miao Li, Ting-Yan Li, Lin-Yan Zhang, Rui-Ling

机构：Baoji Univ Arts & Sci;Shangrao Normal Univ;Gansu Univ Chinese Med

来源：JOURNAL OF ORGANIC CHEMISTRY  2023年88卷6期

JCR：一分区

影响因子：3.3