甘肃中医药大学机构知识库

成果/Result

1Isorhamnetin Promotes MKN-45 Gastric Cancer Cell Apoptosis by Inhibiting PI3K-Mediated Adaptive Autophagy in a Hypoxic Environment被引量：36收藏 分享

作者：Li, Chenghao Li, Jiawei Li, Yan Li, Ling Luo, Yali

机构：Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY  2021年69卷29期

JCR：一分区

影响因子：5.895

关键词：isorhamnetin   apoptosis   autophagy   PI3K   gastric cancer  

2Mechanisms and treatment of atherosclerosis: focus on macrophages被引量：33收藏 分享

作者：Zhang, LingNa Li, JiaWei Kou, YuShun Shen, LuFan Wang, Hong

机构：Gansu Univ Chinese Med;Gansu Prov Hosp;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2024年15卷

JCR：一分区

影响因子：5.9

关键词：atherosclerosis   polarization of M1/M2 macrophages   targeted macrophage therapy   formation of atherosclerosis   source of macrophages  

3The role of lncRNA NEAT1 in human cancer chemoresistance被引量：28收藏 分享

作者：Long, Feng Li, Xue Pan, Jingyu Ye, Hailin Di, Cuixia

机构：Gansu Univ Chinese Med;Chinese Acad Sci

来源：CANCER CELL INTERNATIONAL  2024年24卷1期

JCR：二分区

影响因子：6

关键词：Cancer   Chemotherapy resistance   NEAT1   Mechanism of action  

4Trajectory Analysis Unveils Reelin's Role in the Directed Migration of Granule Cells in the Dentate Gyrus被引量：20收藏 分享

作者：Wang, Shaobo Brunne, Bianka Zhao, Shanting Chai, Xuejun Li, Jiawei

机构：Ctr Mol Neurobiol ZMNH;Univ Freiburg;Northwest A&F Univ;Univ Med Ctr Hamburg Eppendorf;Univ Freiburg

来源：JOURNAL OF NEUROSCIENCE  2018年38卷1期

JCR：一分区

影响因子：6.074

关键词：Dab1 phosphorylation   hippocampus   live imaging   neuronal migration   reeler-like   Reelin  

5Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer被引量：19收藏 分享

作者：Li, Ling Jin, Xiao-jie Li, Jia-wei Li, Cheng-hao Zhou, Shuang-yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chongqing Univ Posts & Telecommun;Gansu Univ Chinese Med

来源：CANCER SCIENCE  2021年112卷5期

JCR：二分区

影响因子：6.518

关键词：gastric cancer   Guiqi Baizhu prescription   molecular docking   molecular dynamics simulation   MST analysis   network pharmacology  

6Effects of Liraglutide Combined with Insulin on Oxidative Stress and Serum MCP-1 and NF-κB Levels in Type 2 Diabetes被引量：17收藏 分享

作者：Liu, Xia Huang, Jinwen Li, Jiawei Mao, Qinghua He, Jirui

机构：Lanzhou Univ;Gansu Peoples Hosp;Gansu Univ Tradit Chinese Med;First Peoples Hosp Jining

来源：JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN  2019年29卷3期

JCR：四分区

影响因子：0.426

关键词：Liraglutide   Insulin   Type 2 diabetes   Blood glucose   MCP-1   NF-kappa B  

7Astragaloside IV alleviates cytarabine-induced intestinal mucositis by remodeling macrophage polarization through AKT signaling被引量：17收藏 分享

作者：Li, Jun-Jie Li, Ya-Ling Chu, Wei Li, Gao-Qin Zhang, Min

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：PHYTOMEDICINE  2023年109卷

JCR：一分区

影响因子：6.7

关键词：Cytarabine   Intestinal mucositis   Macrophage polarization   Astragaloside IV   AKT  

8Deciphering the Active Compounds and Mechanisms of HSbdF for Treating ALI via Integrating Chemical Bioinformatics Analysis被引量：15收藏 分享

作者：Wang, Yanru Jin, Xiaojie Fan, Qin Li, Chenghao Zhang, Min

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chinese Acad Sci;Dalian Univ

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：Traditional Chinese medicine   Huashi Baidu formula   acute lung injury   inflammation   oxidative stress   apoptosis  

9METTL3 Inhibition Restores PD-L1 Expression and CD8⁺ T-cell Cytotoxic Function in Immunotherapy-Treated Gastric Cancer被引量：8收藏 分享

作者：Fang, Ming Li, Yaling Wang, Peng Wang, Yanan Wang, Xiaoqian

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Prov Hosp;Gansu Univ Chinese Med

来源：CANCER IMMUNOLOGY RESEARCH  2025年13卷7期

JCR：一分区

影响因子：12.02

10Transitioning from molecular methods to therapeutic methods: An in-depth analysis of glioblastoma (Review)被引量：7收藏 分享

作者：Han, Hongxi Du, Aichao Li, Jinwen Han, Hongyan Feng, Peng

机构：Lanzhou Univ;Gansu Univ Tradit Chinese Med;Tianshui First Peoples Hosp;Lanzhou Univ Basic Med Sci

来源：ONCOLOGY REPORTS  2025年53卷4期

JCR：三分区

影响因子：4.136

关键词：glioblastoma   molecular mechanism   signaling pathway   therapy   assessment  

11The gut microbiota in osteoporosis: dual roles and therapeutic prospects被引量：6收藏 分享

作者：Xie, Xingwen Liu, Hao Wan, Kangwei Li, Jiawen Qi, Peng

机构：Gansu Univ Tradit Chinese Med;Gansu Univ Tradit Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2025年16卷

JCR：一分区

影响因子：8.787

关键词：gut-bone axis   short-chain fatty acids   osteoimmunology   FMT   probiotics   bone mineral density  

12To study the protective effect of Huangqi Baihe Granules on Radiation brain injury based on network pharmacology and experiment被引量：6收藏 分享

作者：Liu, Xiuzhu Li, Jiawei Wang, Yanru Wu, Bingbing Wang, Siyu

机构：Gansu Univ Chinese Med;940th Hosp Chinese Peoples Liberat Army Joint Supp;Gansu Univ Tradit Chinese Med

来源：JOURNAL OF ETHNOPHARMACOLOGY  2023年315卷

JCR：一分区

影响因子：4.8

关键词：Radiation brain injury   Network pharmacology   Huangqi baihe Granules   Oxidative stress   Inflammation  

13Harnessing extracellular vesicles to tame inflammation: a new strategy for atherosclerosis therapy被引量：5收藏 分享

作者：Li, Jiawei Wen, Tianliang Li, Xiaoran Cheng, Ruoyao Shen, Junyi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2025年16卷

JCR：一分区

影响因子：8.787

关键词：atherosclerosis   extracellular vesicles   exosomes   microvesicles   intercellular communication   biomarkers   nanotherapy  

14Association of Copper with Atherosclerosis and Treatment Strategies被引量：2收藏 分享

作者：Li, Jiawei Yi, Lin Zhang, Lingna Shen, Lufan Lu, Yuyuan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med

来源：JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH  2025年

JCR：三分区

影响因子：3.216

关键词：Copper   Atherosclerosis   Copper metabolism   Cuproptosis   Copper homeostasis  

15Elucidation of the anti-gastric cancer mechanism of Guiqi Baizhu Formula by integrative approach of chemical bioinformatics被引量：2收藏 分享

作者：Wang, Yanru Li, Jiawei Liu, Xiuzhu Zhang, Yixi Wang, Chao

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Shanxi Datong Univ;Gansu Univ Chinese Med;Minist Educ Peoples Republ China

来源：INTERNATIONAL IMMUNOPHARMACOLOGY  2024年134卷

JCR：一分区

影响因子：4.7

关键词：Guiqi Baizhu Formula   Gastric cancer   Glycyrol   Emodin   IGF1R/PI3K/PDK1   VEGFR2  

16Regulated Cell Death and Inflammatory Signaling in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Strategies被引量：1收藏 分享

作者：Lu, Yuyuan Cui, Jia Cheng, Xueyan Li, Jiawei Zhang, Lingna

机构：Gansu Univ Chinese Med;Gansu Prov Hosp Tradit Chinese Med;Gansu Univ Tradit Chinese Med

来源：JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH  2025年

JCR：三分区

影响因子：3.216

关键词：Diabetic cardiomyopathy   Cell death   Inflammatory signaling   Therapeutic strategies  

17Non-linear association between serum 25-hydroxyvitamin D levels and cardiovascular outcomes: Evidence from NHANES and mendelian randomization analysis被引量：1收藏 分享

作者：Li, Jingwei Song, Zhongyang Hu, Yiming Yan, Jingnan Shen, Yanyun

机构：Gansu Univ Chinese Med;Gansu Prov Cardiovasc Dis Res Inst;Gansu Univ Chinese Med;Gansu Prov Hosp Tradit Chinese Med

来源：NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES  2025年35卷10期

JCR：二分区

影响因子：4.666

关键词：25-hydroxyvitamin D   Cardiovascular disease   NHANES   Mendelian randomization   Dose-response relationship   Epidemiology   Non-linear association  

18Mechanistic insights into how gut homeostasis and immune-system crosstalk shape ankylosing spondylitis被引量：0收藏 分享

作者：Li, Jiawen Xie, Xingwen

机构：Gansu Univ Tradit Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2026年17卷

JCR：一分区

影响因子：8.787

关键词：ankylosing spondylitis   gut  joint axis   gut microbiota   intestinal barrier dysfunction   microbial metabolites   mucosal immunity  

19Comment on: "A comparative analysis of perioperative outcomes in single-port and multi-port retroperitoneal robot-assisted partial nephrectomy: a systematic review and meta-analysis"被引量：0收藏 分享

作者：Li, JiaWei Cheng, RuoYao Bu, FeiYing Wen, TianLiang

机构：Gansu Univ Chinese Med

来源：JOURNAL OF ROBOTIC SURGERY  2025年19卷1期

JCR：二分区

影响因子：2.484

20Comment on: Short-term outcomes of robotic versus laparoscopic gastrectomy for proximal gastric cancer: a systematic review and meta-analysis of propensity score-matched or baseline-balanced retrospective studies被引量：0收藏 分享

作者：Zhang, FuDuo Meng, QingYing Wang, YuanHong Li, JiaWei

机构：Gansu Univ Chinese Med

来源：JOURNAL OF ROBOTIC SURGERY  2025年19卷1期

JCR：二分区

影响因子：2.484

21Research progress on the regulation of interstitial cell of Cajal autophagy and apoptosis crosstalk by traditional Chinese medicine in gastrointestinal motility disorders (vol 351, 120128, 2025)被引量：0收藏 分享

作者：Zhang, Lumei Song, Zhongyang Huang, Xixi Jiang, Bing Shen, Yanyun

机构：Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Prov Hosp Tradit Chinese Med;Tianshui Hosp Tradit Chinese Med;Gansu Res Inst Cardiovasc Dis

来源：JOURNAL OF ETHNOPHARMACOLOGY  2026年367卷

JCR：一分区

影响因子：5.195

22Mechanistic role of gut microbiota metabolites in hypertension-insomnia comorbidity via integrated network pharmacology and molecular dynamics被引量：0收藏 分享

作者：Ma, Rui-Ling Kou, Yu-Shun Wang, Yi-Yuan Wang, Hong Shen, Lu-Fan

机构：Gansu Univ Tradit Chinese Med

来源：SCIENTIFIC REPORTS  2026年16卷1期

JCR：二分区

影响因子：4.997

关键词：Hypertension   Insomnia   Gut microbiota metabolites   Molecular dynamics simulation   Network pharmacology  

23Research progress on the regulation of interstitial cell of Cajal autophagy and apoptosis crosstalk by traditional Chinese medicine in gastrointestinal motility disorders被引量：0收藏 分享

作者：Zhang, Lumei Song, Zhongyang Huang, Xixi Jiang, Bing Shen, Yanyun

机构：Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Prov Hosp Tradit Chinese Med;Tianshui Hosp Tradit Chinese Med;Gansu Res Inst Cardiovasc Dis

来源：JOURNAL OF ETHNOPHARMACOLOGY  2025年351卷

JCR：一分区

影响因子：5.195

关键词：Interstitial cells of Cajal   Autophagy   Apoptosis   Crosstalk   Traditional Chinese medicine   Gastrointestinal motility disorders  

24Identification and multi-layered validation of seven diagnostic biomarkers for dilated cardiomyopathy via integrative machine learning, single-cell transcriptomics, and Mendelian randomization被引量：0收藏 分享

作者：Li, Jingwei Song, Zhongyang Wang, Guanwei Chen, Yuchan Cheng, Jiamiao

机构：Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Inst Cardiovasc Dis;Gansu Univ Chinese Med;Gansu Prov Hosp Tradit Chinese Med

来源：FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY  2026年14卷

JCR：一分区

影响因子：6.081

关键词：co-expression-based functional importance score   diagnostic biomarkers   dilated cardiomyopathy   immune microenvironment   machine learning   Mendelian randomization   single-cell RNA sequencing   WGCNA  

25The role of gut microbiota-immune-endocrine crosstalk in the pathogenesis of osteoporosis被引量：0收藏 分享

作者：Xie, Xingwen Chen, Xin Wang, Zhong Chen, Yangyang Li, Jiawen

机构：Gansu Univ Tradit Chinese Med;Gansu Univ Tradit Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2026年17卷

JCR：一分区

影响因子：8.787

关键词：dysbiosis   estrogen deficiency   gut microbiota   gut-bone axis   immune-endocrine crosstalk   lipopolysaccharide (LPS)-TLR4-NF-kappa B signaling   short-chain fatty acids (SCFAs)   Th17/Treg imbalance  

26Analysis of the toxicological effects of Calycosin to alleviate diethyl phthalate exposure on cognitive impairment by network toxicology and chemical bioinformatics被引量：0收藏 分享

作者：Zhang, Yu Li, Jiawei He, Zhenyu Wang, Xinyu Ma, Huanhuan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：BRAIN RESEARCH BULLETIN  2025年232卷

JCR：三分区

影响因子：3.715

关键词：Diethyl phthalate   Cognitive impairment   Calycosin   Molecular dynamics simulation   Machine learning algorithm  

27Mechanistic insights into gut microbiota-driven autoimmunity in rheumatoid arthritis被引量：0收藏 分享

作者：Li, Jiawen Chen, Xin Xie, Xingwen

机构：Gansu Univ Tradit Chinese Med;Gansu Univ Tradit Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2026年17卷

JCR：一分区

影响因子：8.787

关键词：autoimmunity   dysbiosis   gut microbiota   gut-joint axis   molecular mimicry   rheumatoid arthritis   short-chain fatty acids   Th17/Tregimbalance  

28Identification of Npas4 as a biomarker for CICI by transcriptomics combined with bioinformatics and machine learning approaches被引量：0收藏 分享

作者：He, Zhenyu Ma, Huanhuan Zhang, Yu Chen, Liping Pang, Yueling

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：EXPERIMENTAL NEUROLOGY  2025年391卷

JCR：二分区

影响因子：5.62

关键词：CICI   LASSO   SVM-REF   RF   Npas4   Molecular structure   Biomarker