成果/Result
- 1Review: Effect of Gut Microbiota and Its Metabolite SCFAs on Radiation-Induced Intestinal Injury被引量:55收藏
- 作者:Li, Yangyang Zhang, Yiming Wei, Kongxi He, Jinpeng Ding, Nan
- 机构:Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Inst Cardiovasc Dis;Key Lab Dunhuang Med & Transformat Prov & Ministe
- 来源:FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY 2021年11卷
- JCR:一分区
- 影响因子:6.073
- 关键词:radiotherapy gut microbiota dysbiosis metabolites SCFAs radiation-induced intestinal injury
- 2Duality of Interactions Between TGF-β and TNF-α During Tumor Formation被引量:39收藏
- 作者:Liu, Zhi-wei Zhang, Yi-ming Zhang, Li-ying Zhou, Ting Li, Yang-yang
- 机构:Gansu Univ Chinese Med;First Peoples Hosp Lanzhou City;Key Lab Space Radiobiol Gansu Prov;Chinese Acad Sci;Gansu Univ Chinese Med
- 来源:FRONTIERS IN IMMUNOLOGY 2022年12卷
- JCR:一分区
- 影响因子:7.3
- 关键词:TGF-beta TNF-alpha proliferation apoptosis inflammation genomic instability epithelial-mesenchymal transition
- 3Astragalus polysaccharide inhibits radiation-induced bystander effects by regulating apoptosis in Bone Mesenchymal Stem Cells (BMSCs)被引量:15收藏
- 作者:Zhang, Yi-Ming Zhang, Li-Ying Zhou, Heng Li, Yang-Yang Wei, Kong-Xi
- 机构:Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci
- 来源:CELL CYCLE 2020年19卷22期
- JCR:二分区
- 影响因子:4.534
- 关键词:APS RIBE BMSCs Astragalus Polysaccharide Bystander Effect Apoptosis
- 4参苓白术散对肠道菌群失调幼鼠肺部免疫炎症反应的影响被引量:14收藏
- 作者:武妍琳 刘喜平 贾育新 王小荣 武燕
- 机构:甘肃中医药大学附属医院;甘肃中医药大学基础医学院
- 来源:《中国中医药信息杂志》 2022年29卷11期
- 关键词:肠道菌群 抗生素 参苓白术散 免疫炎症反应 幼鼠
- 摘要:目的观察参苓白术散对抗生素诱导的肠道菌群失调幼鼠肺部免疫炎症反应的影响。方法60只雄性Balb/c幼鼠随机抽取10只作为空白组,其余幼鼠采用混合抗生素灌胃诱导肠道菌群失调,连续21 d,末次灌胃后12 h,按随机数字表法...
- 其他来源数据库:万方期刊数据库同方期刊数据库
- 5Guiqi Baizhu Decoction Alleviates Radiation Inflammation in Rats by Modulating the Composition of the Gut Microbiota被引量:13收藏
- 作者:Zhang, Li-Ying Zhou, Ting Zhang, Yi-Ming Xu, Xiao-Min Li, Yang-Yang
- 机构:Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Chinese Med
- 来源:EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2020年2020卷
- JCR:三分区
- 影响因子:2.63
- 6红芪多糖对GK糖尿病胃轻瘫大鼠胃窦组织MYPT1/p-MYPT1蛋白表达的影响被引量:12收藏
- 作者:万生芳 李雅琪 舒畅 王晓丽 魏昭晖
- 机构:甘肃中医药大学;中国药科大学
- 来源:《时珍国医国药》 2019年30卷1期
- 关键词:糖尿病胃轻瘫 红芪多糖 GK大鼠 胃激素 RhoA/RocK信号通路
- 摘要:目的探讨红芪多糖(HPS)改善GK糖尿病胃轻瘫(DGP)大鼠胃动力的作用机制。方法 12只Wistar大鼠作为正常组,68只GK大鼠高糖高脂饲料不规则喂养8周制备DGP模型,60只成模大鼠随机分为模型组、阳性药组(莫沙必...
- 7Review: Mechanisms and perspective treatment of radioresistance in non-small cell lung cancer被引量:11收藏
- 作者:Zhou, Ting Zhang, Li-Ying He, Jian-Zheng Miao, Zhi-Ming Li, Yang-Yang
- 机构:Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源:FRONTIERS IN IMMUNOLOGY 2023年14卷
- JCR:一分区
- 影响因子:5.7
- 关键词:non-small cell lung cancer radiotherapy radioresistance mechanisms toxicity Traditional Chinese Medicine
- 8Aquaporins: Important players in the cardiovascular pathophysiology被引量:8收藏
- 作者:Zhang, Shangzu Xie, Dingxiong Ma, ChengJun Yan, Chen Li, Yangyang
- 机构:Gansu Univ Tradit Chinese Med;Gansu Univ Chinese Med;Key Lab Dunhuang Med & Transformat Prov & Minister;Gansu Inst Cardiovasc Dis
- 来源:PHARMACOLOGICAL RESEARCH 2022年183卷
- JCR:一分区
- 影响因子:9.3
- 关键词:Aquaporin Cardiovascular system Localization Pathophysiology Modulators
- 9Potential molecular mechanism of Guiqi Baizhu Decoction in radiation-induced intestinal edema by regulating HIF-1a, AQP4 and Na+/ K+-ATPase被引量:6收藏
- 作者:Li, Yangyang Zhang, Liying Zhang, Yiming Miao, Zhiming Liu, Zhiwei
- 机构:Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Key Lab Med & Translat;Gansu Inst Cardiovasc Dis
- 来源:PHYTOMEDICINE 2022年107卷
- JCR:一分区
- 影响因子:7.9
- 关键词:Radiation-induced intestinal edema HIF-1 alpha AQP4 Na+/K+-ATPase Guiqi Baizhu decoction Protective effect
- 10Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy被引量:6收藏
- 作者:Jiang, Bing Feng, Longfei Yang, Tao Guo, Wenjing Li, Yangyang
- 机构:Gansu Univ Tradit Chinese Med;Gansu Prov Canc Hosp;Guangxi Univ Tradit Chinese Med;Gansu Prov Canc Hosp
- 来源:MOLECULAR MEDICINE REPORTS 2023年27卷2期
- JCR:三分区
- 影响因子:3.4
- 关键词:salidroside chloroquine diphosphate liver cancer apoptosis autophagy PI3K Akt mTOR
- 11Cathepsin B: The dawn of tumor therapy被引量:5收藏
- 作者:Liu, Fuxian Zhou, Ting Zhang, Shangzu Li, Yangyang Chen, Yan
- 机构:Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2024年269卷
- JCR:一分区
- 影响因子:7.088
- 关键词:CTSB Cancer Traditional Chinese medicine Autophagy Tumor
- 12Radiation-Induced Bystander Effect on the Genome of Bone Marrow Mesenchymal Stem Cells in Lung Cancer被引量:5收藏
- 作者:Zhang, Yi-Ming Zhang, Li-Ying Li, Yang-Yang Zhou, Heng Miao, Zhi-Ming
- 机构:Gansu Univ Chinese Med;Gansu Inst Cardiovasc Dis;Chinese Acad Sci;Chinese Acad Sci;Minist Educ
- 来源:ANTIOXIDANTS & REDOX SIGNALING 2023年38卷10-12期
- JCR:一分区
- 影响因子:6.6
- 关键词:RIBE lung cancer BMSCs genome instability TNF-alpha TGF-beta 1 HIF-1 alpha
- 13半夏泻心汤含药血清对胃癌来源外泌体诱发腹膜间皮细胞上皮间质转化的影响被引量:4收藏
- 作者:董俊刚 刘喜平 李沛清 王庆苗 朱中博
- 机构:甘肃中医药大学
- 来源:《中国实验方剂学杂志》 2021年27卷21期
- 关键词:胃癌 外泌体 人腹膜间皮细胞 上皮间质转化 半夏泻心汤
- 摘要:目的:探讨半夏泻心汤对胃癌来源外泌体(Exo)诱发人腹膜间皮细胞(HMrSV5)上皮间质转化(EMT)的影响。方法:制备半夏泻心汤含药血清,提取人胃癌NCI-N87细胞外泌体(NCI-N87-Exo),采用透射电镜及蛋白...
- 其他来源数据库:万方期刊数据库同方期刊数据库
- 14Ononin promotes radiosensitivity in lung cancer by inhibiting HIF-1α/ VEGF pathway被引量:3收藏
- 作者:Zhang, Yi-Ming Miao, Zhi-Ming Chen, Ya-Ping Song, Zhang-Bo Li, Yang-Yang
- 机构:Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Qingdao Univ
- 来源:PHYTOMEDICINE 2024年125卷
- JCR:一分区
- 影响因子:6.656
- 关键词:Astragalus membranaceus Ononin Hif-1 alpha VEGF Radiosensitization Lung cancer
- 15Energy metabolism: A critical target of cardiovascular injury被引量:3收藏
- 作者:Li, Qiyang Zhang, Shangzu Yang, Gengqiang Wang, Xin Liu, Fuxian
- 机构:Gansu Univ Chinese Med;Gansu Inst Cardiovasc Dis;Minist Educ
- 来源:BIOMEDICINE & PHARMACOTHERAPY 2023年165卷
- JCR:一分区
- 影响因子:6.9
- 关键词:Energy metabolism Ischemic heart disease Heart failure Mitochondrion Diabetic cardiomyopathy Ischemia reperfusion injury
- 16Crosstalk between autophagy inhibitor and salidroside-induced apoptosis: A novel strategy for autophagy-based treatment of hepatocellular cancer被引量:2收藏
- 作者:Jiang, Bing Cui, Yangyang Ma, Xinxin Zhang, Yanmei Feng, Xin
- 机构:Gansu Univ Tradit Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Prov Canc Hosp;Gansu Prov Canc Hosp;Gansu Prov Canc Hosp
- 来源:INTERNATIONAL IMMUNOPHARMACOLOGY 2023年124卷
- JCR:一分区
- 影响因子:4.8
- 关键词:Salidroside Liver cancer Autophagy Mitochondrial apoptosis Crosstalk PI3K/Akt/mTOR
- 17Research progress on pharmacological effects and mechanisms of cepharanthine and its derivatives被引量:1收藏
- 作者:Shi, Liangliang Wang, Shuaizhe Zhang, Shangzu Wang, Jiawei Chen, Yaping
- 机构:Gansu Univ Tradit Chinese Med;Key Lab Tradit Chinese Med Explorat & Innovat Tran;Key Lab Dunhuang Med & Transformat Prov & Minister
- 来源:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 2023年396卷11期
- JCR:三分区
- 影响因子:3.1
- 关键词:Cepharanthine Derivatives Molecular mechanism Anti-inflammatory Antiviral Antitumor Immunity
- 18基于敦煌《辅行诀》方药整体知识的可视化形式概念分析研究被引量:1收藏
- 作者:李廷保 李永玉 杨鹏斐 高英 何鑫瑜
- 机构:甘肃中医药大学;敦煌医学与转化教育部重点实验室
- 来源:《中国中医药图书情报杂志》 2020年0卷1期
- 关键词:敦煌 《辅行诀》 方药 知识可视化 形式概念
- 摘要:目的用可视化形式概念分析理论,研究敦煌《辅行诀》组方特色。方法将传统研究方法与复杂概念网络生成的形式概念分析法紧密结合,对敦煌《辅行诀》所列方剂、组方概念进行提取和规范化表示,建立敦煌《辅行诀》方药整体知识库,并将其中的...
- 其他来源数据库:万方期刊数据库同方期刊数据库
- 19Top 100 cited research on COVID-19 vaccines: A bibliometric analysis and evidence mapping被引量:1收藏
- 作者:Yu, Liping Xu, Caihua Zhang, Mingyue Zhou, Yongjia Hu, Zhiruo
- 机构:Gansu Rehabil Ctr Hosp;Lanzhou Univ;Lanzhou Univ;Gansu Univ Chinese Med;Gansu Hlth Vocat Coll
- 来源:HUMAN VACCINES & IMMUNOTHERAPEUTICS 2024年20卷1期
- JCR:二分区
- 影响因子:4.526
- 关键词:COVID-19 vaccine bibliometric analysis research topic Vosviewer
- 20A potential marker of radiation based on 16S rDNA in the rat model: Intestinal flora被引量:1收藏
- 作者:Zhang, Liying Miao, Zhiming Li, Yangyang Xu, Xiaomin Zhou, Ting
- 机构:Gansu Univ Chinese Med;Hexi Univ;Gansu Univ Chinese Med
- 来源:PLOS ONE 2023年18卷8期
- JCR:二分区
- 影响因子:2.9
- 21基于中医传承计算平台挖掘敦煌医方《辅行诀》方剂组方用药规律被引量:0收藏
- 作者:霍敏峰 岳娟 刘喜平 朱中博 李永玉
- 机构:甘肃中医药大学;甘肃中医药大学基础医学院
- 来源:《包头医学院学报》 2023年39卷1期
- 关键词:敦煌医方 辅行诀 用药规律 中医传承计算平台 数据挖掘
- 摘要:目的:探索《辅行诀脏腑用药法要》方剂的组方用药规律及其学术思想。方法:整理敦煌《辅行诀脏腑用药法要》方剂,采用中医传承计算平台V3.0软件对所整理方子的组方用药进行分析。结果:共涉及方剂61首,包含中药69味,药物四气以...
- 其他来源数据库:万方期刊数据库同方期刊数据库
- 22RIBE from Multiple Irradiation and the Protective Effects of Astragalus Polysaccharides on Methylation and Cancer-associated Proteins in BMSCs被引量:0收藏
- 作者:Zhang, Liying Zhou, Ting Zhang, Yiming Wang, Lei Li, Yangyang
- 机构:Gansu Univ Chinese Med;Chinese Acad Chinese Med Sci;Yangzhou Univ;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源:PHARMACOGNOSY MAGAZINE 2024年20卷2期
- JCR:四分区
- 影响因子:0.948
- 关键词:Radiation bystander effect astragalus polysaccharide methylation deterioration risk
- 23Shenling Baizhu Decoction treats ulcerative colitis of spleen-deficiency and dampness obstruction types by targeting 'gut microbiota and galactose metabolism-bone marrow' axis被引量:0收藏
- 作者:Li, Yongyu Zhu, Zhongbo He, Shu Tang, Jing Zhang, Yanmei
- 机构:Gansu Univ Chinese Med
- 来源:JOURNAL OF ETHNOPHARMACOLOGY 2024年335卷
- JCR:一分区
- 影响因子:5.195
- 关键词:Shenlin Baizhu decoction Ulcerative colitis with spleen deficiency and dampness obstruction 'Gut microbiota-galactose metabolism-bone marrow' axis Galactose metabolism Endogenous bone marrow mesenchymal stem cells homing
- 24Multidimensional screening of Astragalus membranaceus small molecules to mitigate carbon ion radiation-induced bystander effects被引量:0收藏
- 作者:Zhang, Liying Zhang, Yiming Li, Yangyang Li, Qiyang Zhang, Shangzu
- 机构:Gansu Univ Chinese Med;Gansu Inst Cardiovasc Dis;Chinese Acad Sci;Chinese Acad Sci
- 来源:JOURNAL OF PHARMACEUTICAL ANALYSIS 2024年14卷10期
- JCR:一分区
- 影响因子:14.026
- 关键词:Radiotherapy BMSCs HIF-1 alpha Astragalus membranaceus Isoliquiritigenin Non-small cell lung
- 25How consistent are the key recommendations, and what is the quality of guidelines and expert consensus regarding paediatric cow's milk protein allergy?被引量:0收藏
- 作者:Li, Tengfei Zheng, Qingyong Zhang, Mingyue Li, Yiyi Zhou, Yongjia
- 机构:Gansu Univ Chinese Med;Lanzhou Univ;Lanzhou Univ;Gansu Prov Matern & Child Hlth Hosp
- 来源:EUROPEAN JOURNAL OF PEDIATRICS 2024年183卷8期
- JCR:一分区
- 影响因子:3.86
- 关键词:AGREE II AGREE-REX Cow's milk protein allergy Guidelines Expert consensus Quality assessment