甘肃中医药大学机构知识库

成果/Result

1Review: Effect of Gut Microbiota and Its Metabolite SCFAs on Radiation-Induced Intestinal Injury被引量：102收藏 分享

作者：Li, Yangyang Zhang, Yiming Wei, Kongxi He, Jinpeng Ding, Nan

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Inst Cardiovasc Dis;Key Lab Dunhuang Med & Transformat Prov & Ministe

来源：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY  2021年11卷

JCR：一分区

影响因子：6.073

关键词：radiotherapy   gut microbiota   dysbiosis   metabolites   SCFAs   radiation-induced intestinal injury  

2Carbon ion radiotherapy triggers immunogenic cell death and sensitizes melanoma to anti-PD-1 therapy in mice被引量：72收藏 分享

作者：Zhou, Heng Tu, Chen Yang, Pengfei Li, Jin Kepp, Oliver

机构：Chinese Acad Sci;Chinese Acad Sci;Univ Chinese Acad Sci;Xi An Jiao Tong Univ;Lanzhou Univ

来源：ONCOIMMUNOLOGY  2022年11卷1期

影响因子：7.2

关键词：Carbon ion radiotherapy   immunogenic cell death   melanoma   anti-PD-1 therapy  

3Duality of Interactions Between TGF-β and TNF-α During Tumor Formation被引量：66收藏 分享

作者：Liu, Zhi-wei Zhang, Yi-ming Zhang, Li-ying Zhou, Ting Li, Yang-yang

机构：Gansu Univ Chinese Med;First Peoples Hosp Lanzhou City;Key Lab Space Radiobiol Gansu Prov;Chinese Acad Sci;Gansu Univ Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2022年12卷

JCR：一分区

影响因子：7.3

关键词：TGF-beta   TNF-alpha   proliferation   apoptosis   inflammation   genomic instability   epithelial-mesenchymal transition  

4Review: Mechanisms and perspective treatment of radioresistance in non-small cell lung cancer被引量：60收藏 分享

作者：Zhou, Ting Zhang, Li-Ying He, Jian-Zheng Miao, Zhi-Ming Li, Yang-Yang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2023年14卷

JCR：一分区

影响因子：5.7

关键词：non-small cell lung cancer   radiotherapy   radioresistance mechanisms   toxicity   Traditional Chinese Medicine  

5Cathepsin B: The dawn of tumor therapy被引量：41收藏 分享

作者：Liu, Fuxian Zhou, Ting Zhang, Shangzu Li, Yangyang Chen, Yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY  2024年269卷

JCR：一分区

影响因子：5.9

关键词：CTSB   Cancer   Traditional Chinese medicine   Autophagy   Tumor  

6Ononin promotes radiosensitivity in lung cancer by inhibiting HIF-1α/ VEGF pathway被引量：39收藏 分享

作者：Zhang, Yi-Ming Miao, Zhi-Ming Chen, Ya-Ping Song, Zhang-Bo Li, Yang-Yang

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Qingdao Univ

来源：PHYTOMEDICINE  2024年125卷

JCR：一分区

影响因子：8.3

关键词：Astragalus membranaceus   Ononin   Hif-1 alpha   VEGF   Radiosensitization   Lung cancer  

7Carbon ion radiotherapy boosts anti-tumour immune responses by inhibiting myeloid-derived suppressor cells in melanoma-bearing mice被引量：34收藏 分享

作者：Zhou, Heng Yang, Pengfei Li, Haining Zhang, Liying Li, Jin

机构：Chinese Acad Sci;Chinese Acad Sci;Univ Chinese Acad Sci;Gansu Prov Canc Hosp;Gansu Univ Chinese Med

来源：CELL DEATH DISCOVERY  2021年7卷1期

影响因子：7.113

8Energy metabolism: A critical target of cardiovascular injury被引量：32收藏 分享

作者：Li, Qiyang Zhang, Shangzu Yang, Gengqiang Wang, Xin Liu, Fuxian

机构：Gansu Univ Chinese Med;Gansu Inst Cardiovasc Dis;Minist Educ

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年165卷

JCR：一分区

影响因子：6.9

关键词：Energy metabolism   Ischemic heart disease   Heart failure   Mitochondrion   Diabetic cardiomyopathy   Ischemia   reperfusion injury  

9Astragalus polysaccharide inhibits radiation-induced bystander effects by regulating apoptosis in Bone Mesenchymal Stem Cells (BMSCs)被引量：23收藏 分享

作者：Zhang, Yi-Ming Zhang, Li-Ying Zhou, Heng Li, Yang-Yang Wei, Kong-Xi

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci

来源：CELL CYCLE  2020年19卷22期

JCR：二分区

影响因子：4.534

关键词：APS   RIBE   BMSCs   Astragalus Polysaccharide   Bystander Effect   Apoptosis  

10Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-κB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs)被引量：21收藏 分享

作者：Zhang, Liying Luo, Yali Lu, Zhiwei He, Jinpeng Wang, Lei

机构：Gansu Univ Tradit Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Tradit Chinese Med

来源：MEDICAL SCIENCE MONITOR  2018年24卷

影响因子：1.98

关键词：Bystander Effect   Mesenchymal Stromal Cells   Polysaccharides  

11Guiqi Baizhu Decoction Alleviates Radiation Inflammation in Rats by Modulating the Composition of the Gut Microbiota被引量：20收藏 分享

作者：Zhang, Li-Ying Zhou, Ting Zhang, Yi-Ming Xu, Xiao-Min Li, Yang-Yang

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Chinese Med

来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE  2020年2020卷

JCR：三分区

影响因子：2.63

12Aquaporins: Important players in the cardiovascular pathophysiology被引量：18收藏 分享

作者：Zhang, Shangzu Xie, Dingxiong Ma, ChengJun Yan, Chen Li, Yangyang

机构：Gansu Univ Tradit Chinese Med;Gansu Univ Chinese Med;Key Lab Dunhuang Med & Transformat Prov & Minister;Gansu Inst Cardiovasc Dis

来源：PHARMACOLOGICAL RESEARCH  2022年183卷

JCR：一分区

影响因子：9.3

关键词：Aquaporin   Cardiovascular system   Localization   Pathophysiology   Modulators  

13Ionizing radiation downregulates estradiol synthesis via endoplasmic reticulum stress and inhibits the proliferation of estrogen receptor-positive breast cancer cells被引量：16收藏 分享

作者：Yang, Pengfei Feng, Xiu Li, Jin Zhang, Tianyi Sheng, Chengyan

机构：Chinese Acad Sci;Chinese Acad Sci;Univ Chinese Acad Sci;Lanzhou Univ;Gansu Univ Chinese Med

来源：CELL DEATH & DISEASE  2021年12卷11期

JCR：一分区

影响因子：9.696

14Potential molecular mechanism of Guiqi Baizhu Decoction in radiation-induced intestinal edema by regulating HIF-1a, AQP4 and Na⁺/ K⁺-ATPase被引量：13收藏 分享

作者：Li, Yangyang Zhang, Liying Zhang, Yiming Miao, Zhiming Liu, Zhiwei

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Key Lab Med & Translat;Gansu Inst Cardiovasc Dis

来源：PHYTOMEDICINE  2022年107卷

JCR：一分区

影响因子：7.9

关键词：Radiation-induced intestinal edema   HIF-1 alpha   AQP4   Na+/K+-ATPase   Guiqi Baizhu decoction   Protective effect  

15Astragalus Polysaccharide Eases G1 Phase-Correlative Bystander Effects through Mediation of TGF-βR/MAPK/ROS Signal Pathway After Carbon Ion Irradiation in BMSCs被引量：12收藏 分享

作者：Zhang, Li-Ying Yong, Wen-Xing Wang, Lei Zhang, Li-Xin Zhang, Yi-Ming

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci

来源：AMERICAN JOURNAL OF CHINESE MEDICINE  2019年47卷3期

JCR：一分区

影响因子：3.682

关键词：BMSCs   Bystander Effect   Astragalus Polysaccharide   MAPK   TGF-beta  

16Targeting tumor-associated macrophage polarization with traditional Chinese medicine active ingredients: Dual reversal of chemoresistance and immunosuppression in tumor microenvironment被引量：12收藏 分享

作者：Qi, Yafeng Yan, Jingnan Huang, Xixi Jiang, Xiaodan Li, Rongrong

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Prov Hosp Tradit Chinese Med

来源：PHARMACOLOGICAL RESEARCH  2025年216卷

JCR：一分区

影响因子：10.334

关键词：Natural product   Tumor-associated macrophage (TAM)   Chemoresistance   Immunosuppression   Therapeutic potential  

17Research progress on pharmacological effects and mechanisms of cepharanthine and its derivatives被引量：11收藏 分享

作者：Shi, Liangliang Wang, Shuaizhe Zhang, Shangzu Wang, Jiawei Chen, Yaping

机构：Gansu Univ Tradit Chinese Med;Key Lab Tradit Chinese Med Explorat & Innovat Tran;Key Lab Dunhuang Med & Transformat Prov & Minister

来源：NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY  2023年396卷11期

JCR：三分区

影响因子：3.1

关键词：Cepharanthine   Derivatives   Molecular mechanism   Anti-inflammatory   Antiviral   Antitumor   Immunity  

18Osthole ameliorates simulated microgravity-induced bone loss through down-regulation of miR-34c-5p被引量：9收藏 分享

作者：Feng, Xiu Zhou, Heng Zhang, Yanan Yang, Pengfei Bai, Hao

机构：Chinese Acad Sci;Chinese Acad Sci;Univ Chinese Acad Sci;Gansu Univ Tradit Chinese Med;Lanzhou Univ

来源：ACTA ASTRONAUTICA  2021年183卷

JCR：一分区

影响因子：2.954

关键词：Osthole   miR-34c-5p   Simulated microgravity   Bone loss  

19Association between splenectomy and chronic thromboembolic pulmonary hypertension: a systematic review and meta-analysis被引量：8收藏 分享

作者：Zhang, Liyan Yan, Peijing Yang, Kehu Wu, Shanlian Bai, Yuping

机构：Gansu Univ Chinese Med;Gansu Prov Hosp;Lanzhou Univ;Lanzhou Univ;Sichuan Univ

来源：BMJ OPEN  2021年11卷2期

JCR：二分区

影响因子：3.007

关键词：respiratory physiology   adult surgery   adult thoracic medicine  

20Radiation-Induced Bystander Effect on the Genome of Bone Marrow Mesenchymal Stem Cells in Lung Cancer被引量：6收藏 分享

作者：Zhang, Yi-Ming Zhang, Li-Ying Li, Yang-Yang Zhou, Heng Miao, Zhi-Ming

机构：Gansu Univ Chinese Med;Gansu Inst Cardiovasc Dis;Chinese Acad Sci;Chinese Acad Sci;Minist Educ

来源：ANTIOXIDANTS & REDOX SIGNALING  2023年38卷10-12期

JCR：一分区

影响因子：6.6

关键词：RIBE   lung cancer   BMSCs   genome instability   TNF-alpha   TGF-beta 1   HIF-1 alpha  

21Targeting lactate metabolism in the tumor microenvironment: Immunomodulation and prospects for antitumor therapy被引量：6收藏 分享

作者：Yan, Jingnan Qi, Yafeng Liu, Yeyuan Jiang, Xiaodan Li, Yangyang

机构：Gansu Univ Tradit Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Prov Hosp Tradit Chinese Med

来源：INTERNATIONAL IMMUNOPHARMACOLOGY  2025年164卷

JCR：一分区

影响因子：5.714

关键词：Lactate metabolism   Tumor microenvironment   Immune cells   Targeted therapy   Traditional Chinese medicine   Traditional Chinese medicine  

22Jianpi Huatan Tongfu granule alleviates inflammation and improves intestinal flora in patients with acute exacerbation of chronic obstructive pulmonary disease被引量：6收藏 分享

作者：Yong, Wenxing Zhang, Liying Chen, Yuexuan Li, Juan Liu, Yongqi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Hangzhou Hosp Tradit Chinese Med;Gansu Univ Chinese Med

来源：JOURNAL OF INTERNATIONAL MEDICAL RESEARCH  2020年48卷4期

JCR：四分区

影响因子：1.671

关键词：Jianpi Huatan Tongfu granule   acute exacerbation of chronic obstructive pulmonary disease   inflammation   intestinal flora   16S rDNA   cytokines   C-reactive protein   lung function   dyspnea  

23Meta-analysis of right ventricular function in patients with aortic stenosis after transfemoral aortic valve replacement or surgical aortic valve replacement被引量：5收藏 分享

作者：Cao, Yunshan Singh, Vikas Wang, Aqian Zhang, Liyan He, Tingting

机构：Gansu Prov Hosp;Shanxi Med Univ;Gansu Prov Hosp;Tianjin Med Univ;Tianjin Med Univ

来源：THERAPEUTIC ADVANCES IN CHRONIC DISEASE  2020年11卷

JCR：二分区

影响因子：5.091

关键词：aortic valve stenosis   AS   right ventricule   right ventricular function   SAVR   surgical aortic valve replacement   TAVI   TAVR   TF-TAVR   transcatheter aortic valve implantation   transcatheter aortic valve replacement   transfemoral-aortic valve replacement  

24A potential marker of radiation based on 16S rDNA in the rat model: Intestinal flora被引量：5收藏 分享

作者：Zhang, Liying Miao, Zhiming Li, Yangyang Xu, Xiaomin Zhou, Ting

机构：Gansu Univ Chinese Med;Hexi Univ;Gansu Univ Chinese Med

来源：PLOS ONE  2023年18卷8期

JCR：二分区

影响因子：2.9

25Guiqi Baizhu decoction enhances radiosensitivity in non-small cell lung cancer by inhibiting the HIF-1α/DNA-PKcs axis-mediated DNA repair被引量：4收藏 分享

作者：Li, Yangyang Yang, Gengqiang Li, Qiyang Zhang, Yiming Zhang, Shangzu

机构：Gansu Univ Chinese Med;Qingdao Univ;Hubei Univ Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Prov Canc Hosp

来源：PHYTOMEDICINE  2025年140卷

JCR：一分区

影响因子：6.656

关键词：Traditional Chinese medicine (TCM)   Guiqi baizhu decoction (GQBZD)   Radiosensitivity   Non-small cell lung cancer (NSCLC)   Non-homologous end joining (NHEJ) repair  

26Multidimensional screening of Astragalus membranaceus small molecules to mitigate carbon ion radiation-induced bystander effects被引量：4收藏 分享

作者：Zhang, Liying Zhang, Yiming Li, Yangyang Li, Qiyang Zhang, Shangzu

机构：Gansu Univ Chinese Med;Gansu Inst Cardiovasc Dis;Chinese Acad Sci;Chinese Acad Sci

来源：JOURNAL OF PHARMACEUTICAL ANALYSIS  2024年14卷10期

JCR：一分区

影响因子：8.9

关键词：Radiotherapy   BMSCs   HIF-1 alpha   Astragalus membranaceus   Isoliquiritigenin   Non-small cell lung  

27The Role of MiR-5094 as a Proliferation Suppressor during Cellular Radiation Response via Downregulating STAT5b被引量：3收藏 分享

作者：Ding, Nan Hua, Junrui He, Jinpeng Lu, Dong Wei, Wenjun

机构：Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Tradit Chinese Med;Soochow Univ

来源：JOURNAL OF CANCER  2020年11卷8期

JCR：二分区

影响因子：4.207

关键词：microRNA   radiation   miR-5094   STAT5b   proliferation  

28Efficacy and safety of targeted drugs in advanced or metastatic gastric and gastroesophageal junction cancer: A network meta-analysis被引量：3收藏 分享

作者：Gong, Hongxia Su, Yun Zhao, Lixia Ma, Li Zhang, Liying

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chinese Minist Educ & Gansu Prov;Gansu Univ Chinese Med;Lanzhou Univ

来源：JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS  2022年47卷4期

JCR：四分区

影响因子：2.145

关键词：gastric cancer   gastroesophageal junction cancer   network meta-analysis   targeted drugs  

29Circulating leptin levels in thyroid dysfunction: a systematic review and meta-analysis被引量：3收藏 分享

作者：Liu, Shanshan Ma, Jun Zhang, Leyuan Yang, Yanlong Han, Ziqi

机构：Gansu Univ Chinese Med;Univ Elect Sci & Technol China;Gansu Prov Hosp;Clin Res Ctr Metab Dis

来源：BMC ENDOCRINE DISORDERS  2025年25卷1期

JCR：三分区

影响因子：3.263

关键词：Leptin   Thyroid dysfunction   Thyroid hormone   Meta-analysis  

30Development and external validation of a machine learning model to predict diabetic nephropathy in T1DM patients in the real-world被引量：3收藏 分享

作者：Du, Zouxi Liu, Xiaoning Li, Jiayu Min, Hang Ma, Yuhu

机构：Lanzhou Univ;Gansu Prov Hosp;Lanzhou Univ;Gansu Univ Tradit Chinese Med;Lanzhou Univ

来源：ACTA DIABETOLOGICA  2024年

JCR：二分区

影响因子：2.9

关键词：Type 1 diabetes mellitus   Diabetic nephropathy   Machine learning   Interpretable model   External validation