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成果/Result
- 1Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease被引量：34收藏
- 作者：He, Jianzheng Li, Xu Yang, Shipei Li, Yaling Lin, Xingyao
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Ttadit Chinese Med;Northwestern Polytech Univ
- 来源：FOOD & FUNCTION 2021年12卷17期
- JCR：一分区
- 影响因子：6.317
- 2Extension of Drosophila Lifespan by Astragalus polysaccharide through a Mechanism Dependent on Antioxidant and Insulin/IGF-1 Signaling被引量：25收藏
- 作者：Yang, Fujia Xiu, Minghui Yang, Shipei Li, Xu Tuo, Wenjuan
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med
- 来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2021年2021卷
- JCR：三分区
- 影响因子：2.65
- 3Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster被引量：18收藏
- 作者：Li, Xu Yang, Shipei Wang, Shuwei Shi, Yan Dai, Yuting
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Lanzhou Univ
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023年234卷
- JCR：一分区
- 影响因子：7.7
- 关键词：Astragalus polysaccharide Intestinal homeostasis Intestinal stem cells Sleeping disturbances Alzheimer's disease Drosophila melanogaster
- 4Drosophila as a Model to Study the Mechanism of Nociception被引量：17收藏
- 作者：He, Jianzheng Li, Botong Han, Shuzhen Zhang, Yuan Liu, Kai
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ
- 来源：FRONTIERS IN PHYSIOLOGY 2022年13卷
- JCR：一分区
- 影响因子：4
- 关键词：nociception conserved genetics nociceptive sensory neurons behavioral assay Drosophila melanogaster
- 5Protective effect of astragalus membranaceus and its bioactive compounds against the intestinal inflammation in Drosophila被引量：14收藏
- 作者：He, Jianzheng Li, Xu Yang, Shipei Shi, Yan Dai, Yuting
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：FRONTIERS IN PHARMACOLOGY 2022年13卷
- JCR：一分区
- 影响因子：5.6
- 关键词：inflammatory bowel disease Astragalus membranaceus intestinal homeostasis bioactive compounds Drosophila melanogaster
- 6Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease被引量：12收藏
- 作者：Xiu, Minghui Wang, Yixuan Yang, Dan Zhang, Xueyan Dai, Yuting
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med
- 来源：FRONTIERS IN PHARMACOLOGY 2022年13卷
- JCR：一分区
- 影响因子：5.6
- 关键词：inflammatory bowel disease Drosophila melanogaster natural products drug discovery molecular pathways
- 7Flos puerariae ameliorates the intestinal inflammation of Drosophila via modulating the Nrf2/Keap1, JAK-STAT and Wnt signaling被引量：11收藏
- 作者：Yang, Shipei Li, Xu Xiu, Minghui Dai, Yuting Wan, Shengfang
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：FRONTIERS IN PHARMACOLOGY 2022年13卷
- JCR：一分区
- 影响因子：5.6
- 关键词：Flos Puerariae intestinal inflammation intestinal homeostasis Drosophila melanogaster intestinal stem cells ROS
- 8Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease被引量：10收藏
- 作者：Li, Botong Wang, Yixuan Jiang, Xiaolin Du, Hongwei Shi, Yan
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Polit Sci & Law
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2023年164卷
- JCR：一分区
- 影响因子：6.9
- 关键词：Nrf2 ARE signaling pathway Inflammatory bowel disease Nature compounds Natural extract Compound recipe Gut microbe
- 9Angelica sinensis polysaccharide extends lifespan and ameliorates aging-related diseases via insulin and TOR signaling pathways, and antioxidant ability in Drosophila被引量：8收藏
- 作者：Tuo, Wenjuan Wang, Shuwei Shi, Yan Cao, Wangjie Liu, Yongqi
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023年241卷
- JCR：一分区
- 影响因子：7.7
- 关键词：Angelica sinensis polysaccharide Healthy aging Intestinal homeostasis Sleep disorders Alzheimer's disease
- 10Exposure to cytarabine causes side effects on adult development and physiology and induces intestinal damage via apoptosis in Drosophila被引量：5收藏
- 作者：Han, Shuzhen Xiu, Minghui Li, Shuang Shi, Yan Wang, Xiaoqian
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2023年159卷
- JCR：一分区
- 影响因子：6.9
- 关键词：Cytarabine Side effects Drosophila melanogaster Intestine Apoptosis
- 11The antioxidant effects of hedysarum polybotrys polysaccharide in extending lifespan and ameliorating aging-related diseases in Drosophila melanogaster被引量：3收藏
- 作者：Yang, Shipei Xiu, Minghui Li, Xu Shi, Yan Wang, Shuwei
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023年241卷
- JCR：一分区
- 影响因子：7.7
- 关键词：Hedysarum polybotrys polysaccharide Anti-aging Intestinal homeostasis Sleep disturbances Alzheimer's disease Drosophila melanogaster
- 12Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 pathways被引量：2收藏
- 作者：Li, Botong Xiu, Minghui He, Li Zhou, Shihong Yi, Simeng
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ
- 来源：JOURNAL OF ETHNOPHARMACOLOGY 2024年322卷
- JCR：一分区
- 影响因子：4.8
- 关键词：San huang pill Dunhuang ancient medical prescription Ulcerative colitis Drosophila melanogaster Signaling pathway Bioactive compounds
- 13Olfactory Senses Modulate Food Consumption and Physiology in Drosophila melanogaster被引量：2收藏
- 作者：He, Jianzheng Tuo, Wenjuan Zhang, Xueyan Dai, Yuting Fang, Ming
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Univ Chinese Med
- 来源：FRONTIERS IN BEHAVIORAL NEUROSCIENCE 2022年16卷
- JCR：二分区
- 影响因子：3
- 关键词：olfaction food consumption physiology stress resistance Drosophila melanogaster
- 14Irinotecan cause the side effects on development and adult physiology, and induces intestinal damage via innate immune response and oxidative damage in Drosophila被引量：1收藏
- 作者：He, Jianzheng Han, Shuzhen Wang, Yixuan Kang, Qian Wang, Xiaoqian
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Prov Hosp;Gansu Univ Chinese Med;Gansu Univ Chinese Med
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2023年169卷
- JCR：一分区
- 影响因子：6.9
- 关键词：Chemotherapy Irinotecan Side effects Drosophila melanogaster Intestine
- 15Drosophila as a model to study the mechanism of nociception (vol 13, 854124, 2022)被引量：1收藏
- 作者：He, Jianzheng Li, Botong Han, Shuzhen Zhang, Yuan Liu, Kai
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ
- 来源：FRONTIERS IN PHYSIOLOGY 2022年13卷
- JCR：一分区
- 影响因子：4
- 关键词：nociception conserved genetics nociceptive sensory neurons behavioral assay Drosophila melanogaster
- 16The protective effect and bioactive compounds of Astragalus membranaceus against neurodegenerative disorders via alleviating oxidative stress in Drosophila被引量：0收藏
- 作者：Dai, Yuting Wang, Yixuan Kang, Qian Wu, Yifan Liu, Yongqi
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ
- 来源：FASEB JOURNAL 2024年38卷13期
- JCR：一分区
- 影响因子：5.834
- 关键词：antioxidant Astragalus membranaceus bioactive compounds Drosophila melanogaster neurodegenerative diseases
- 17Therapeutic potential of Astragalus membranaceus-Pueraria lobata decoction for the treatment of chemotherapy bowel injury被引量：0收藏
- 作者：Wang, Yixuan Qin, Yujie Kang, Qian Wang, Huinan Zhou, Shihong
- 机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Second Prov Peoples Hosp Gansu
- 来源：FASEB JOURNAL 2024年38卷19期
- JCR：一分区
- 影响因子：5.834
- 关键词：Astragalus membranaceus chemotherapy Drosophila melanogaster intestinal mucositis molecular mechanism Pueraria lobata decoction
