甘肃中医药大学机构知识库

成果/Result

1Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease被引量：39收藏 分享

作者：He, Jianzheng Li, Xu Yang, Shipei Li, Yaling Lin, Xingyao

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Ttadit Chinese Med;Northwestern Polytech Univ

来源：FOOD & FUNCTION  2021年12卷17期

JCR：一分区

影响因子：6.317

2Extension of Drosophila Lifespan by Astragalus polysaccharide through a Mechanism Dependent on Antioxidant and Insulin/IGF-1 Signaling被引量：29收藏 分享

作者：Yang, Fujia Xiu, Minghui Yang, Shipei Li, Xu Tuo, Wenjuan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med

来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE  2021年2021卷

JCR：三分区

影响因子：2.65

3Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster被引量：23收藏 分享

作者：Li, Xu Yang, Shipei Wang, Shuwei Shi, Yan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Lanzhou Univ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年234卷

JCR：一分区

影响因子：7.7

关键词：Astragalus polysaccharide   Intestinal homeostasis   Intestinal stem cells   Sleeping disturbances   Alzheimer's disease   Drosophila melanogaster  

4Protective effect of astragalus membranaceus and its bioactive compounds against the intestinal inflammation in Drosophila被引量：20收藏 分享

作者：He, Jianzheng Li, Xu Yang, Shipei Shi, Yan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：inflammatory bowel disease   Astragalus membranaceus   intestinal homeostasis   bioactive compounds   Drosophila melanogaster  

5Drosophila as a Model to Study the Mechanism of Nociception被引量：19收藏 分享

作者：He, Jianzheng Li, Botong Han, Shuzhen Zhang, Yuan Liu, Kai

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：FRONTIERS IN PHYSIOLOGY  2022年13卷

JCR：一分区

影响因子：4

关键词：nociception   conserved genetics   nociceptive sensory neurons   behavioral assay   Drosophila melanogaster  

6Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease被引量：18收藏 分享

作者：Xiu, Minghui Wang, Yixuan Yang, Dan Zhang, Xueyan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：inflammatory bowel disease   Drosophila melanogaster   natural products   drug discovery   molecular pathways  

7Flos puerariae ameliorates the intestinal inflammation of Drosophila via modulating the Nrf2/Keap1, JAK-STAT and Wnt signaling被引量：15收藏 分享

作者：Yang, Shipei Li, Xu Xiu, Minghui Dai, Yuting Wan, Shengfang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：Flos Puerariae   intestinal inflammation   intestinal homeostasis   Drosophila melanogaster   intestinal stem cells   ROS  

8Angelica sinensis polysaccharide extends lifespan and ameliorates aging-related diseases via insulin and TOR signaling pathways, and antioxidant ability in Drosophila被引量：14收藏 分享

作者：Tuo, Wenjuan Wang, Shuwei Shi, Yan Cao, Wangjie Liu, Yongqi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年241卷

JCR：一分区

影响因子：7.7

关键词：Angelica sinensis polysaccharide   Healthy aging   Intestinal homeostasis   Sleep disorders   Alzheimer's disease  

9Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease被引量：12收藏 分享

作者：Li, Botong Wang, Yixuan Jiang, Xiaolin Du, Hongwei Shi, Yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Polit Sci & Law

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年164卷

JCR：一分区

影响因子：6.9

关键词：Nrf2   ARE signaling pathway   Inflammatory bowel disease   Nature compounds   Natural extract   Compound recipe   Gut microbe  

10Exposure to cytarabine causes side effects on adult development and physiology and induces intestinal damage via apoptosis in Drosophila被引量：10收藏 分享

作者：Han, Shuzhen Xiu, Minghui Li, Shuang Shi, Yan Wang, Xiaoqian

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年159卷

JCR：一分区

影响因子：6.9

关键词：Cytarabine   Side effects   Drosophila melanogaster   Intestine   Apoptosis  

11Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 pathways被引量：7收藏 分享

作者：Li, Botong Xiu, Minghui He, Li Zhou, Shihong Yi, Simeng

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：JOURNAL OF ETHNOPHARMACOLOGY  2024年322卷

JCR：一分区

影响因子：4.8

关键词：San huang pill   Dunhuang ancient medical prescription   Ulcerative colitis   Drosophila melanogaster   Signaling pathway   Bioactive compounds  

12The antioxidant effects of hedysarum polybotrys polysaccharide in extending lifespan and ameliorating aging-related diseases in Drosophila melanogaster被引量：7收藏 分享

作者：Yang, Shipei Xiu, Minghui Li, Xu Shi, Yan Wang, Shuwei

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年241卷

JCR：一分区

影响因子：7.7

关键词：Hedysarum polybotrys polysaccharide   Anti-aging   Intestinal homeostasis   Sleep disturbances   Alzheimer's disease   Drosophila melanogaster  

13The protective effect and bioactive compounds of Astragalus membranaceus against neurodegenerative disorders via alleviating oxidative stress in Drosophila被引量：3收藏 分享

作者：Dai, Yuting Wang, Yixuan Kang, Qian Wu, Yifan Liu, Yongqi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：FASEB JOURNAL  2024年38卷13期

JCR：一分区

影响因子：5.834

关键词：antioxidant   Astragalus membranaceus   bioactive compounds   Drosophila melanogaster   neurodegenerative diseases  

14Olfactory Senses Modulate Food Consumption and Physiology in Drosophila melanogaster被引量：2收藏 分享

作者：He, Jianzheng Tuo, Wenjuan Zhang, Xueyan Dai, Yuting Fang, Ming

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN BEHAVIORAL NEUROSCIENCE  2022年16卷

JCR：二分区

影响因子：3

关键词：olfaction   food consumption   physiology   stress resistance   Drosophila melanogaster  

15Irinotecan cause the side effects on development and adult physiology, and induces intestinal damage via innate immune response and oxidative damage in Drosophila被引量：2收藏 分享

作者：He, Jianzheng Han, Shuzhen Wang, Yixuan Kang, Qian Wang, Xiaoqian

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Prov Hosp;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年169卷

JCR：一分区

影响因子：6.9

关键词：Chemotherapy   Irinotecan   Side effects   Drosophila melanogaster   Intestine  

16Drosophila as a model to study the mechanism of nociception (vol 13, 854124, 2022)被引量：1收藏 分享

作者：He, Jianzheng Li, Botong Han, Shuzhen Zhang, Yuan Liu, Kai

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：FRONTIERS IN PHYSIOLOGY  2022年13卷

JCR：一分区

影响因子：4

关键词：nociception   conserved genetics   nociceptive sensory neurons   behavioral assay   Drosophila melanogaster  

17Therapeutic potential of Astragalus membranaceus-Pueraria lobata decoction for the treatment of chemotherapy bowel injury被引量：0收藏 分享

作者：Wang, Yixuan Qin, Yujie Kang, Qian Wang, Huinan Zhou, Shihong

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Second Prov Peoples Hosp Gansu

来源：FASEB JOURNAL  2024年38卷19期

JCR：一分区

影响因子：5.834

关键词：Astragalus membranaceus   chemotherapy   Drosophila melanogaster   intestinal mucositis   molecular mechanism   Pueraria lobata decoction  

18Caffeic Acid Protects Against Ulcerative Colitis via Inhibiting Mitochondrial Apoptosis and Immune Overactivation in Drosophila被引量：0收藏 分享

作者：Xiu, Minghui Li, Botong He, Li Shi, Yan Zhang, Yongxuan

机构：Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med;Qinghai Univ;Gansu Univ Chinese Med

来源：DRUG DESIGN DEVELOPMENT AND THERAPY  2025年19卷

JCR：二分区

影响因子：4.319

关键词：ulcerative colitis   caffeic acid   toll and Imd pathways   apoptosis   Drosophila melanogaster  

19Acute hypoxia induces sleep disorders via sima/HIF-1α regulation of circadian rhythms in adult Drosophila被引量：0收藏 分享

作者：Wang, Shuwei Zhou, Shihong Jiang, Xiaolin Yang, Dan He, Jianzheng

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Shandong Univ Dezhou Hosp

来源：COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY  2025年294卷

JCR：一分区

影响因子：4.52

关键词：Acute hypoxia   Circadian rhythms   Sleep disorders   Drosophila  

20Dunhuang Dabupi Decoction and its active components alleviate ulcerative colitis by activating glutathione metabolism and inhibiting JAK-STAT pathway in Drosophila and mice被引量：0收藏 分享

作者：He, Li Zhang, Yongxuan Li, Jiangnan Chen, Dandan Yue, Shiqi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：JOURNAL OF ETHNOPHARMACOLOGY  2025年346卷

JCR：一分区

影响因子：5.195

关键词：Dabupi decoction   Active components   Dunhuang medicine   Ulcerative colitis   Glutathione metabolism   JAK-STAT pathway