甘肃中医药大学机构知识库

成果/Result

1Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease被引量：34收藏 分享

作者：He, Jianzheng Li, Xu Yang, Shipei Li, Yaling Lin, Xingyao

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Ttadit Chinese Med;Northwestern Polytech Univ

来源：FOOD & FUNCTION  2021年12卷17期

JCR：一分区

影响因子：6.317

2Extension of Drosophila Lifespan by Astragalus polysaccharide through a Mechanism Dependent on Antioxidant and Insulin/IGF-1 Signaling被引量：25收藏 分享

作者：Yang, Fujia Xiu, Minghui Yang, Shipei Li, Xu Tuo, Wenjuan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med

来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE  2021年2021卷

JCR：三分区

影响因子：2.65

3Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster被引量：18收藏 分享

作者：Li, Xu Yang, Shipei Wang, Shuwei Shi, Yan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Lanzhou Univ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年234卷

JCR：一分区

影响因子：7.7

关键词：Astragalus polysaccharide   Intestinal homeostasis   Intestinal stem cells   Sleeping disturbances   Alzheimer's disease   Drosophila melanogaster  

4Drosophila as a Model to Study the Mechanism of Nociception被引量：17收藏 分享

作者：He, Jianzheng Li, Botong Han, Shuzhen Zhang, Yuan Liu, Kai

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：FRONTIERS IN PHYSIOLOGY  2022年13卷

JCR：一分区

影响因子：4

关键词：nociception   conserved genetics   nociceptive sensory neurons   behavioral assay   Drosophila melanogaster  

5Protective effect of astragalus membranaceus and its bioactive compounds against the intestinal inflammation in Drosophila被引量：14收藏 分享

作者：He, Jianzheng Li, Xu Yang, Shipei Shi, Yan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：inflammatory bowel disease   Astragalus membranaceus   intestinal homeostasis   bioactive compounds   Drosophila melanogaster  

6Single-organic component g-C_3.6N₄ achieves superior photoactivity antibacterial被引量：13收藏 分享

作者：Miao, Ruoyan Liu, Hu Lei, Qian Zhong, Lvling Zhang, Liang

机构：Xian Univ Architecture & Technol;Xian Univ Architecture & Technol;Beijing Technol & Business Univ;Gansu Univ Chinese Med

来源：CHEMICAL ENGINEERING JOURNAL  2022年440卷

JCR：一分区

影响因子：15.1

关键词：Flexible membrane   Schiff base   Single organic component   C3.6N4   Photocatalysis antibacterial  

7Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease被引量：12收藏 分享

作者：Xiu, Minghui Wang, Yixuan Yang, Dan Zhang, Xueyan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：inflammatory bowel disease   Drosophila melanogaster   natural products   drug discovery   molecular pathways  

8Flos puerariae ameliorates the intestinal inflammation of Drosophila via modulating the Nrf2/Keap1, JAK-STAT and Wnt signaling被引量：11收藏 分享

作者：Yang, Shipei Li, Xu Xiu, Minghui Dai, Yuting Wan, Shengfang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：Flos Puerariae   intestinal inflammation   intestinal homeostasis   Drosophila melanogaster   intestinal stem cells   ROS  

9Review: Mechanisms and perspective treatment of radioresistance in non-small cell lung cancer被引量：11收藏 分享

作者：Zhou, Ting Zhang, Li-Ying He, Jian-Zheng Miao, Zhi-Ming Li, Yang-Yang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2023年14卷

JCR：一分区

影响因子：5.7

关键词：non-small cell lung cancer   radiotherapy   radioresistance mechanisms   toxicity   Traditional Chinese Medicine  

10Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease被引量：10收藏 分享

作者：Li, Botong Wang, Yixuan Jiang, Xiaolin Du, Hongwei Shi, Yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Polit Sci & Law

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年164卷

JCR：一分区

影响因子：6.9

关键词：Nrf2   ARE signaling pathway   Inflammatory bowel disease   Nature compounds   Natural extract   Compound recipe   Gut microbe  

11Angelica sinensis polysaccharide extends lifespan and ameliorates aging-related diseases via insulin and TOR signaling pathways, and antioxidant ability in Drosophila被引量：8收藏 分享

作者：Tuo, Wenjuan Wang, Shuwei Shi, Yan Cao, Wangjie Liu, Yongqi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年241卷

JCR：一分区

影响因子：7.7

关键词：Angelica sinensis polysaccharide   Healthy aging   Intestinal homeostasis   Sleep disorders   Alzheimer's disease  

1215-PGDH Expression in Gastric Cancer: A Potential Role in Anti-Tumor Immunity被引量：5收藏 分享

作者：Li, Yaling Li, Junjie Dong, Juanjuan Zhang, Lei Liu, Donglin

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chinese Minist Educ & Gansu Prov;Gansu Univ Chinese Med

来源：CANCER MANAGEMENT AND RESEARCH  2020年12卷

JCR：三分区

影响因子：3.989

关键词：gastric cancer   15-PGDH   immunosuppression   FOXP3   Tregs  

13Exposure to cytarabine causes side effects on adult development and physiology and induces intestinal damage via apoptosis in Drosophila被引量：5收藏 分享

作者：Han, Shuzhen Xiu, Minghui Li, Shuang Shi, Yan Wang, Xiaoqian

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年159卷

JCR：一分区

影响因子：6.9

关键词：Cytarabine   Side effects   Drosophila melanogaster   Intestine   Apoptosis  

14Optimal Formula of Angelica sinensis Ameliorates Memory Deficits in β-amyloid Protein-induced Alzheimer's Disease Rat Model被引量：4收藏 分享

作者：Wang, Hu-Ping Wu, Hong-Yan Ma, Chun-Lin Zeng, Qing-Tao Zhu, Kai-Min

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：CURRENT MEDICAL SCIENCE  2022年42卷1期

JCR：四分区

影响因子：2.4

关键词：optimal formula of Angelica sinensis   Alzheimer's disease   amyloid beta aggregation   oxidative stress   neuroinflammation  

15The antioxidant effects of hedysarum polybotrys polysaccharide in extending lifespan and ameliorating aging-related diseases in Drosophila melanogaster被引量：3收藏 分享

作者：Yang, Shipei Xiu, Minghui Li, Xu Shi, Yan Wang, Shuwei

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年241卷

JCR：一分区

影响因子：7.7

关键词：Hedysarum polybotrys polysaccharide   Anti-aging   Intestinal homeostasis   Sleep disturbances   Alzheimer's disease   Drosophila melanogaster  

16Guiqi Baizhu prescription ameliorates cytarabine-induced intestinal mucositis by targeting JAK2 to inhibit M1 macrophage polarization被引量：3收藏 分享

作者：Chu, Wei Li, Ya-ling Li, Jun-jie Lin, Jia Li, Mi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;First Hosp Lanzhou Univ

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年164卷

JCR：一分区

影响因子：6.9

关键词：Intestinal mucositis   JAK2   STAT1   Macrophage polarization   Acridine   Senkyunolide A  

17Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 pathways被引量：2收藏 分享

作者：Li, Botong Xiu, Minghui He, Li Zhou, Shihong Yi, Simeng

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：JOURNAL OF ETHNOPHARMACOLOGY  2024年322卷

JCR：一分区

影响因子：4.8

关键词：San huang pill   Dunhuang ancient medical prescription   Ulcerative colitis   Drosophila melanogaster   Signaling pathway   Bioactive compounds  

18Olfactory Senses Modulate Food Consumption and Physiology in Drosophila melanogaster被引量：2收藏 分享

作者：He, Jianzheng Tuo, Wenjuan Zhang, Xueyan Dai, Yuting Fang, Ming

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN BEHAVIORAL NEUROSCIENCE  2022年16卷

JCR：二分区

影响因子：3

关键词：olfaction   food consumption   physiology   stress resistance   Drosophila melanogaster  

19Irinotecan cause the side effects on development and adult physiology, and induces intestinal damage via innate immune response and oxidative damage in Drosophila被引量：1收藏 分享

作者：He, Jianzheng Han, Shuzhen Wang, Yixuan Kang, Qian Wang, Xiaoqian

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Prov Hosp;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年169卷

JCR：一分区

影响因子：6.9

关键词：Chemotherapy   Irinotecan   Side effects   Drosophila melanogaster   Intestine  

20Drosophila as a model to study the mechanism of nociception (vol 13, 854124, 2022)被引量：1收藏 分享

作者：He, Jianzheng Li, Botong Han, Shuzhen Zhang, Yuan Liu, Kai

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：FRONTIERS IN PHYSIOLOGY  2022年13卷

JCR：一分区

影响因子：4

关键词：nociception   conserved genetics   nociceptive sensory neurons   behavioral assay   Drosophila melanogaster  

21Huangqi Baihe Granules alleviate hypobaric hypoxia-induced acute lung injury in rats by suppressing oxidative stress and the TLR4/NF-κB/NLRP3 inflammatory pathway被引量：1收藏 分享

作者：Zeng, Yuanding Cao, Wangjie Huang, Yong Zhang, Han Li, Congyi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med

来源：JOURNAL OF ETHNOPHARMACOLOGY  2024年324卷

JCR：一分区

影响因子：5.195

关键词：Huangqi Baihe Granule   Hypobaric hypoxia   Acute lung injury   Oxidative stress   Inflammation  

22The protective effect and bioactive compounds of Astragalus membranaceus against neurodegenerative disorders via alleviating oxidative stress in Drosophila被引量：0收藏 分享

作者：Dai, Yuting Wang, Yixuan Kang, Qian Wu, Yifan Liu, Yongqi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：FASEB JOURNAL  2024年38卷13期

JCR：一分区

影响因子：5.834

关键词：antioxidant   Astragalus membranaceus   bioactive compounds   Drosophila melanogaster   neurodegenerative diseases  

23Changing Cinnamaldehyde Skeleton Achieves Antibacterial Nanoswitch被引量：0收藏 分享

作者：Zhao, Xiaoying Miao, Ruoyan Xu, Tianze Du, Xiaolong Zhang, Xueyan

机构：Xian Univ Architecture & Technol;Nanjing Univ;Gansu Univ Chinese Med;Beijing Technol & Business Univ;Chinese Acad Sci

来源：ACS APPLIED MATERIALS & INTERFACES  2024年16卷14期

JCR：一分区

影响因子：10.383

关键词：cinnamaldehyde derivatives   organic nanosheets   electron cloud density   antibacterial nanoswitch   antibacterial mechanism  

24Therapeutic potential of Astragalus membranaceus-Pueraria lobata decoction for the treatment of chemotherapy bowel injury被引量：0收藏 分享

作者：Wang, Yixuan Qin, Yujie Kang, Qian Wang, Huinan Zhou, Shihong

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Second Prov Peoples Hosp Gansu

来源：FASEB JOURNAL  2024年38卷19期

JCR：一分区

影响因子：5.834

关键词：Astragalus membranaceus   chemotherapy   Drosophila melanogaster   intestinal mucositis   molecular mechanism   Pueraria lobata decoction  

25The involvement of oxidative stress and the TLR4/NF-κB/NLRP3 pathway in acute lung injury induced by high-altitude hypoxia被引量：0收藏 分享

作者：Cao, Wangjie Zeng, Yuanding Su, Yun Gong, Hongxia He, Jianzheng

机构：Gansu Univ Tradit Chinese Med;Gansu Univ Chinese Med;Key Lab Theoret Phys Gansu Prov & Minist Level

来源：IMMUNOBIOLOGY  2024年229卷3期

JCR：四分区

影响因子：3.152

关键词：High -altitude hypoxia   Acute lung injury   Oxidative stress   Inflammatory response   TLR4/NF-kappa B/NLRP3 pathway