甘肃中医药大学机构知识库

成果/Result

1A Review of the Pharmacological Action of Astragalus Polysaccharide被引量：266收藏 分享

作者：Zheng, Yijun Ren, Weiyu Zhang, Lina Zhang, Yuemei Liu, Dongling

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Univ Leeds;Lanzhou Univ

来源：FRONTIERS IN PHARMACOLOGY  2020年11卷

JCR：一分区

影响因子：5.811

关键词：Astragalus polysaccharide   preparation   chemical composition   pharmacological action   immune regulation   anti-aging   anti-tumor   regulation of blood glucose  

2Review: Effect of Gut Microbiota and Its Metabolite SCFAs on Radiation-Induced Intestinal Injury被引量：68收藏 分享

作者：Li, Yangyang Zhang, Yiming Wei, Kongxi He, Jinpeng Ding, Nan

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Inst Cardiovasc Dis;Key Lab Dunhuang Med & Transformat Prov & Ministe

来源：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY  2021年11卷

JCR：一分区

影响因子：6.073

关键词：radiotherapy   gut microbiota   dysbiosis   metabolites   SCFAs   radiation-induced intestinal injury  

3Duality of Interactions Between TGF-β and TNF-α During Tumor Formation被引量：45收藏 分享

作者：Liu, Zhi-wei Zhang, Yi-ming Zhang, Li-ying Zhou, Ting Li, Yang-yang

机构：Gansu Univ Chinese Med;First Peoples Hosp Lanzhou City;Key Lab Space Radiobiol Gansu Prov;Chinese Acad Sci;Gansu Univ Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2022年12卷

JCR：一分区

影响因子：7.3

关键词：TGF-beta   TNF-alpha   proliferation   apoptosis   inflammation   genomic instability   epithelial-mesenchymal transition  

4The unusual variations of photoluminescence and afterglow properties in monoclinic ZrO₂ by annealing被引量：40收藏 分享

作者：Wang, Zhilong Zhang, Jiachi Zheng, Guisen Liu, Yongqi Zhao, Yali

机构：Gansu Univ Tradit Chinese Med;Lanzhou Univ

来源：JOURNAL OF LUMINESCENCE  2012年132卷11期

JCR：二分区

影响因子：2.144

关键词：Optical materials   Optical properties  

5Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease被引量：39收藏 分享

作者：He, Jianzheng Li, Xu Yang, Shipei Li, Yaling Lin, Xingyao

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Ttadit Chinese Med;Northwestern Polytech Univ

来源：FOOD & FUNCTION  2021年12卷17期

JCR：一分区

影响因子：6.317

6A polysaccharide-based micelle-hydrogel synergistic therapy system for diabetes and vascular diabetes complications treatment被引量：39收藏 分享

作者：Wen, Na Lu, Shaoyu Xu, Xiubin Ning, Piao Wang, Zengqiang

机构：Lanzhou Univ;Guangzhou Univ;Gansu Univ Tradit Chinese Med;Lanzhou City Univ

来源：MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS  2019年100卷

JCR：一分区

影响因子：8.457

关键词：Micelle   Hydrogel   Glucose-responsive   Synergistic therapy   Thrombolysis  

7A rapid and specific fluorescent probe based on aggregation-induced emission enhancement for mercury ion detection in living systems被引量：30收藏 分享

作者：An, Yong Li, Bo Yu, Yongzhi Zhou, Yucen Yi, Jianfeng

机构：Gansu Univ Chinese Med;Gansu Univ Key Lab Mol Med & Chinese Med Prevent &;Gansu Univ Chinese Med;Gansu Prov Canc Hosp;China West Normal Univ

来源：JOURNAL OF HAZARDOUS MATERIALS  2024年465卷

JCR：一分区

影响因子：12.2

关键词：Aggregation-induced emission   Mercury ions   Peptide   Oxidative stress   Biomimetic probe  

8Extension of Drosophila Lifespan by Astragalus polysaccharide through a Mechanism Dependent on Antioxidant and Insulin/IGF-1 Signaling被引量：29收藏 分享

作者：Yang, Fujia Xiu, Minghui Yang, Shipei Li, Xu Tuo, Wenjuan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med

来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE  2021年2021卷

JCR：三分区

影响因子：2.65

9Isorhamnetin Promotes MKN-45 Gastric Cancer Cell Apoptosis by Inhibiting PI3K-Mediated Adaptive Autophagy in a Hypoxic Environment被引量：23收藏 分享

作者：Li, Chenghao Li, Jiawei Li, Yan Li, Ling Luo, Yali

机构：Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY  2021年69卷29期

JCR：一分区

影响因子：5.895

关键词：isorhamnetin   apoptosis   autophagy   PI3K   gastric cancer  

10Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster被引量：23收藏 分享

作者：Li, Xu Yang, Shipei Wang, Shuwei Shi, Yan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Lanzhou Univ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年234卷

JCR：一分区

影响因子：7.7

关键词：Astragalus polysaccharide   Intestinal homeostasis   Intestinal stem cells   Sleeping disturbances   Alzheimer's disease   Drosophila melanogaster  

11Review: Mechanisms and perspective treatment of radioresistance in non-small cell lung cancer被引量：22收藏 分享

作者：Zhou, Ting Zhang, Li-Ying He, Jian-Zheng Miao, Zhi-Ming Li, Yang-Yang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2023年14卷

JCR：一分区

影响因子：5.7

关键词：non-small cell lung cancer   radiotherapy   radioresistance mechanisms   toxicity   Traditional Chinese Medicine  

12Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-κB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs)被引量：21收藏 分享

作者：Zhang, Liying Luo, Yali Lu, Zhiwei He, Jinpeng Wang, Lei

机构：Gansu Univ Tradit Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Tradit Chinese Med

来源：MEDICAL SCIENCE MONITOR  2018年24卷

影响因子：1.98

关键词：Bystander Effect   Mesenchymal Stromal Cells   Polysaccharides  

13Protective effect of astragalus membranaceus and its bioactive compounds against the intestinal inflammation in Drosophila被引量：20收藏 分享

作者：He, Jianzheng Li, Xu Yang, Shipei Shi, Yan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：inflammatory bowel disease   Astragalus membranaceus   intestinal homeostasis   bioactive compounds   Drosophila melanogaster  

14Drosophila as a Model to Study the Mechanism of Nociception被引量：19收藏 分享

作者：He, Jianzheng Li, Botong Han, Shuzhen Zhang, Yuan Liu, Kai

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：FRONTIERS IN PHYSIOLOGY  2022年13卷

JCR：一分区

影响因子：4

关键词：nociception   conserved genetics   nociceptive sensory neurons   behavioral assay   Drosophila melanogaster  

15Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease被引量：18收藏 分享

作者：Xiu, Minghui Wang, Yixuan Yang, Dan Zhang, Xueyan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：inflammatory bowel disease   Drosophila melanogaster   natural products   drug discovery   molecular pathways  

16Ononin promotes radiosensitivity in lung cancer by inhibiting HIF-1α/ VEGF pathway被引量：17收藏 分享

作者：Zhang, Yi-Ming Miao, Zhi-Ming Chen, Ya-Ping Song, Zhang-Bo Li, Yang-Yang

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Qingdao Univ

来源：PHYTOMEDICINE  2024年125卷

JCR：一分区

影响因子：6.656

关键词：Astragalus membranaceus   Ononin   Hif-1 alpha   VEGF   Radiosensitization   Lung cancer  

17Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer被引量：17收藏 分享

作者：Li, Ling Jin, Xiao-jie Li, Jia-wei Li, Cheng-hao Zhou, Shuang-yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chongqing Univ Posts & Telecommun;Gansu Univ Chinese Med

来源：CANCER SCIENCE  2021年112卷5期

JCR：二分区

影响因子：6.518

关键词：gastric cancer   Guiqi Baizhu prescription   molecular docking   molecular dynamics simulation   MST analysis   network pharmacology  

18Astragalus polysaccharide inhibits radiation-induced bystander effects by regulating apoptosis in Bone Mesenchymal Stem Cells (BMSCs)被引量：17收藏 分享

作者：Zhang, Yi-Ming Zhang, Li-Ying Zhou, Heng Li, Yang-Yang Wei, Kong-Xi

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci

来源：CELL CYCLE  2020年19卷22期

JCR：二分区

影响因子：4.534

关键词：APS   RIBE   BMSCs   Astragalus Polysaccharide   Bystander Effect   Apoptosis  

19Guiqi Baizhu Decoction Alleviates Radiation Inflammation in Rats by Modulating the Composition of the Gut Microbiota被引量：16收藏 分享

作者：Zhang, Li-Ying Zhou, Ting Zhang, Yi-Ming Xu, Xiao-Min Li, Yang-Yang

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Chinese Med

来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE  2020年2020卷

JCR：三分区

影响因子：2.63

20Astragalus Saponins and Liposome Constitute an Efficacious Adjuvant Formulation for Cancer Vaccines被引量：15收藏 分享

作者：Zhang, Xiao-Ping Li, Ying-Dong Luo, Lu-Lu Liu, Yong-Qi Li, Yang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Lanzhou Univ;Tumor Hosp Gansu Prov;Lanzhou Univ

来源：CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS  2018年33卷1期

JCR：二分区

影响因子：1.894

关键词：adjuvant formulation   Astragalus saponins   tumor vaccine  

21Flos puerariae ameliorates the intestinal inflammation of Drosophila via modulating the Nrf2/Keap1, JAK-STAT and Wnt signaling被引量：15收藏 分享

作者：Yang, Shipei Li, Xu Xiu, Minghui Dai, Yuting Wan, Shengfang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：Flos Puerariae   intestinal inflammation   intestinal homeostasis   Drosophila melanogaster   intestinal stem cells   ROS  

22Angelica sinensis polysaccharide extends lifespan and ameliorates aging-related diseases via insulin and TOR signaling pathways, and antioxidant ability in Drosophila被引量：14收藏 分享

作者：Tuo, Wenjuan Wang, Shuwei Shi, Yan Cao, Wangjie Liu, Yongqi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年241卷

JCR：一分区

影响因子：7.7

关键词：Angelica sinensis polysaccharide   Healthy aging   Intestinal homeostasis   Sleep disorders   Alzheimer's disease  

23Huangqi Shengmai Yin Protects against Radiation-Induced Cardiac Fibrosis Injury by Regulating the TGF-1/Smads and MMPs被引量：14收藏 分享

作者：Gu, Jing Liu, Yongqi Wu, Hongyan Li, Hailong Liu, Kai

机构：Gansu Univ Tradit Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Univ Tradit Chinese Med

来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE  2019年2019卷

JCR：三分区

影响因子：1.813

24Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease被引量：12收藏 分享

作者：Li, Botong Wang, Yixuan Jiang, Xiaolin Du, Hongwei Shi, Yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Polit Sci & Law

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年164卷

JCR：一分区

影响因子：6.9

关键词：Nrf2   ARE signaling pathway   Inflammatory bowel disease   Nature compounds   Natural extract   Compound recipe   Gut microbe  

25Deciphering the Active Compounds and Mechanisms of HSBDF for Treating ALI via Integrating Chemical Bioinformatics Analysis被引量：12收藏 分享

作者：Wang, Yanru Jin, Xiaojie Fan, Qin Li, Chenghao Zhang, Min

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chinese Acad Sci;Dalian Univ

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：Traditional Chinese medicine   Huashi Baidu formula   acute lung injury   inflammation   oxidative stress   apoptosis  

26Dihydroartemisinin Sensitizes Mutant p53 (R248Q)-Expressing Hepatocellular Carcinoma Cells to Doxorubicin by Inhibiting P-gp Expression被引量：12收藏 分享

作者：Yang, Yue He, Jianxin Chen, Jing Lin, Li Liu, Yongqi

机构：Lanzhou Univ;Gansu Univ Chinese Med

来源：BIOMED RESEARCH INTERNATIONAL  2019年2019卷

JCR：三分区

影响因子：2.276

27Formaldehyde induces toxic effects and regulates the expression of damage response genes in BM-MSCs被引量：12收藏 分享

作者：She, Yali Li, Yi Liu, Yongqi Asai, Guli Sun, Shaobo

机构：Gansu Agr Univ;Gansu Univ Tradit Chinese Med;Gansu Univ Tradit Chinese Med;Gansu Univ Tradit Chinese Med;Lanzhou Univ

来源：ACTA BIOCHIMICA ET BIOPHYSICA SINICA  2013年45卷12期

影响因子：2.089

关键词：comet assay   DNA-protein crosslinks   sister chromatid exchange   micronuclei   PCR array  

28Astragalus Polysaccharide Eases G1 Phase-Correlative Bystander Effects through Mediation of TGF-βR/MAPK/ROS Signal Pathway After Carbon Ion Irradiation in BMSCs被引量：12收藏 分享

作者：Zhang, Li-Ying Yong, Wen-Xing Wang, Lei Zhang, Li-Xin Zhang, Yi-Ming

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci

来源：AMERICAN JOURNAL OF CHINESE MEDICINE  2019年47卷3期

JCR：一分区

影响因子：3.682

关键词：BMSCs   Bystander Effect   Astragalus Polysaccharide   MAPK   TGF-beta  

29Bellidifolin Inhibits Proliferation of A549 Cells by Regulating STAT3/COX-2 Expression and Protein Activity被引量：11收藏 分享

作者：Li Yan Luo Yali Li Chenghao Feng Caiqin Zhu Zhongbo

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ Peoples Republ China;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：JOURNAL OF ONCOLOGY  2020年2020卷

JCR：二分区

影响因子：4.375

30Cathepsin B: The dawn of tumor therapy被引量：11收藏 分享

作者：Liu, Fuxian Zhou, Ting Zhang, Shangzu Li, Yangyang Chen, Yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY  2024年269卷

JCR：一分区

影响因子：7.088

关键词：CTSB   Cancer   Traditional Chinese medicine   Autophagy   Tumor