甘肃中医药大学机构知识库

成果/Result

1A Review of the Pharmacological Action of Astragalus Polysaccharide被引量：297收藏 分享

作者：Zheng, Yijun Ren, Weiyu Zhang, Lina Zhang, Yuemei Liu, Dongling

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Univ Leeds;Lanzhou Univ

来源：FRONTIERS IN PHARMACOLOGY  2020年11卷

JCR：一分区

影响因子：5.811

关键词：Astragalus polysaccharide   preparation   chemical composition   pharmacological action   immune regulation   anti-aging   anti-tumor   regulation of blood glucose  

2Review: Effect of Gut Microbiota and Its Metabolite SCFAs on Radiation-Induced Intestinal Injury被引量：82收藏 分享

作者：Li, Yangyang Zhang, Yiming Wei, Kongxi He, Jinpeng Ding, Nan

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Inst Cardiovasc Dis;Key Lab Dunhuang Med & Transformat Prov & Ministe

来源：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY  2021年11卷

JCR：一分区

影响因子：6.073

关键词：radiotherapy   gut microbiota   dysbiosis   metabolites   SCFAs   radiation-induced intestinal injury  

3Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease被引量：57收藏 分享

作者：He, Jianzheng Li, Xu Yang, Shipei Li, Yaling Lin, Xingyao

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Ttadit Chinese Med;Northwestern Polytech Univ

来源：FOOD & FUNCTION  2021年12卷17期

JCR：一分区

影响因子：6.317

4Duality of Interactions Between TGF-β and TNF-α During Tumor Formation被引量：55收藏 分享

作者：Liu, Zhi-wei Zhang, Yi-ming Zhang, Li-ying Zhou, Ting Li, Yang-yang

机构：Gansu Univ Chinese Med;First Peoples Hosp Lanzhou City;Key Lab Space Radiobiol Gansu Prov;Chinese Acad Sci;Gansu Univ Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2022年12卷

JCR：一分区

影响因子：7.3

关键词：TGF-beta   TNF-alpha   proliferation   apoptosis   inflammation   genomic instability   epithelial-mesenchymal transition  

5A rapid and specific fluorescent probe based on aggregation-induced emission enhancement for mercury ion detection in living systems被引量：48收藏 分享

作者：An, Yong Li, Bo Yu, Yongzhi Zhou, Yucen Yi, Jianfeng

机构：Gansu Univ Chinese Med;Gansu Univ Key Lab Mol Med & Chinese Med Prevent &;Gansu Univ Chinese Med;Gansu Prov Canc Hosp;China West Normal Univ

来源：JOURNAL OF HAZARDOUS MATERIALS  2024年465卷

JCR：一分区

影响因子：12.2

关键词：Aggregation-induced emission   Mercury ions   Peptide   Oxidative stress   Biomimetic probe  

6Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster被引量：43收藏 分享

作者：Li, Xu Yang, Shipei Wang, Shuwei Shi, Yan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Lanzhou Univ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年234卷

JCR：一分区

影响因子：7.7

关键词：Astragalus polysaccharide   Intestinal homeostasis   Intestinal stem cells   Sleeping disturbances   Alzheimer's disease   Drosophila melanogaster  

7The unusual variations of photoluminescence and afterglow properties in monoclinic ZrO₂ by annealing被引量：40收藏 分享

作者：Wang, Zhilong Zhang, Jiachi Zheng, Guisen Liu, Yongqi Zhao, Yali

机构：Gansu Univ Tradit Chinese Med;Lanzhou Univ

来源：JOURNAL OF LUMINESCENCE  2012年132卷11期

JCR：二分区

影响因子：2.144

关键词：Optical materials   Optical properties  

8A polysaccharide-based micelle-hydrogel synergistic therapy system for diabetes and vascular diabetes complications treatment被引量：39收藏 分享

作者：Wen, Na Lu, Shaoyu Xu, Xiubin Ning, Piao Wang, Zengqiang

机构：Lanzhou Univ;Guangzhou Univ;Gansu Univ Tradit Chinese Med;Lanzhou City Univ

来源：MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS  2019年100卷

JCR：一分区

影响因子：5.88

关键词：Micelle   Hydrogel   Glucose-responsive   Synergistic therapy   Thrombolysis  

9Review: Mechanisms and perspective treatment of radioresistance in non-small cell lung cancer被引量：39收藏 分享

作者：Zhou, Ting Zhang, Li-Ying He, Jian-Zheng Miao, Zhi-Ming Li, Yang-Yang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN IMMUNOLOGY  2023年14卷

JCR：一分区

影响因子：5.7

关键词：non-small cell lung cancer   radiotherapy   radioresistance mechanisms   toxicity   Traditional Chinese Medicine  

10Extension of Drosophila Lifespan by Astragalus polysaccharide through a Mechanism Dependent on Antioxidant and Insulin/IGF-1 Signaling被引量：39收藏 分享

作者：Yang, Fujia Xiu, Minghui Yang, Shipei Li, Xu Tuo, Wenjuan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Tradit Chinese Med

来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE  2021年2021卷

JCR：三分区

影响因子：2.65

11Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease被引量：34收藏 分享

作者：Li, Botong Wang, Yixuan Jiang, Xiaolin Du, Hongwei Shi, Yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Polit Sci & Law

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年164卷

JCR：一分区

影响因子：6.9

关键词：Nrf2   ARE signaling pathway   Inflammatory bowel disease   Nature compounds   Natural extract   Compound recipe   Gut microbe  

12Angelica sinensis polysaccharide extends lifespan and ameliorates aging-related diseases via insulin and TOR signaling pathways, and antioxidant ability in Drosophila被引量：33收藏 分享

作者：Tuo, Wenjuan Wang, Shuwei Shi, Yan Cao, Wangjie Liu, Yongqi

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年241卷

JCR：一分区

影响因子：7.7

关键词：Angelica sinensis polysaccharide   Healthy aging   Intestinal homeostasis   Sleep disorders   Alzheimer's disease  

13Isorhamnetin Promotes MKN-45 Gastric Cancer Cell Apoptosis by Inhibiting PI3K-Mediated Adaptive Autophagy in a Hypoxic Environment被引量：32收藏 分享

作者：Li, Chenghao Li, Jiawei Li, Yan Li, Ling Luo, Yali

机构：Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY  2021年69卷29期

JCR：一分区

影响因子：5.895

关键词：isorhamnetin   apoptosis   autophagy   PI3K   gastric cancer  

14Mechanisms of Alveolar Type 2 Epithelial Cell Death During Acute Lung Injury被引量：30收藏 分享

作者：Qi, Xiaofeng Luo, Yali Xiao, Mengyong Zhang, Qiuju Luo, Jing

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：STEM CELLS  2023年41卷12期

JCR：一分区

影响因子：4

关键词：acute lung injury   alveolar type 2 epithelial cell   apoptosis   necrosis   necroptosis   pyroptosis   autophagic cell death   ferroptosis  

15The Antioxidant Action of Astragali radix: Its Active Components and Molecular Basis被引量：29收藏 分享

作者：Yao, Juan Peng, Ting Shao, Changxin Liu, Yuanyuan Lin, Huanhuan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：MOLECULES  2024年29卷8期

JCR：二分区

影响因子：4.6

关键词：Astragali radix   antioxidant   astragalus polysaccharides   flavonoids compounds   saponins compounds  

16Ononin promotes radiosensitivity in lung cancer by inhibiting HIF-1α/ VEGF pathway被引量：29收藏 分享

作者：Zhang, Yi-Ming Miao, Zhi-Ming Chen, Ya-Ping Song, Zhang-Bo Li, Yang-Yang

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Qingdao Univ

来源：PHYTOMEDICINE  2024年125卷

JCR：一分区

影响因子：8.3

关键词：Astragalus membranaceus   Ononin   Hif-1 alpha   VEGF   Radiosensitization   Lung cancer  

17Protective effect of astragalus membranaceus and its bioactive compounds against the intestinal inflammation in Drosophila被引量：28收藏 分享

作者：He, Jianzheng Li, Xu Yang, Shipei Shi, Yan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：inflammatory bowel disease   Astragalus membranaceus   intestinal homeostasis   bioactive compounds   Drosophila melanogaster  

18Cathepsin B: The dawn of tumor therapy被引量：27收藏 分享

作者：Liu, Fuxian Zhou, Ting Zhang, Shangzu Li, Yangyang Chen, Yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY  2024年269卷

JCR：一分区

影响因子：5.9

关键词：CTSB   Cancer   Traditional Chinese medicine   Autophagy   Tumor  

19Flos puerariae ameliorates the intestinal inflammation of Drosophila via modulating the Nrf2/Keap1, JAK-STAT and Wnt signaling被引量：23收藏 分享

作者：Yang, Shipei Li, Xu Xiu, Minghui Dai, Yuting Wan, Shengfang

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：Flos Puerariae   intestinal inflammation   intestinal homeostasis   Drosophila melanogaster   intestinal stem cells   ROS  

20Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease被引量：23收藏 分享

作者：Xiu, Minghui Wang, Yixuan Yang, Dan Zhang, Xueyan Dai, Yuting

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ;Gansu Univ Chinese Med

来源：FRONTIERS IN PHARMACOLOGY  2022年13卷

JCR：一分区

影响因子：5.6

关键词：inflammatory bowel disease   Drosophila melanogaster   natural products   drug discovery   molecular pathways  

21Drosophila as a Model to Study the Mechanism of Nociception被引量：23收藏 分享

作者：He, Jianzheng Li, Botong Han, Shuzhen Zhang, Yuan Liu, Kai

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：FRONTIERS IN PHYSIOLOGY  2022年13卷

JCR：一分区

影响因子：4

关键词：nociception   conserved genetics   nociceptive sensory neurons   behavioral assay   Drosophila melanogaster  

22Energy metabolism: A critical target of cardiovascular injury被引量：23收藏 分享

作者：Li, Qiyang Zhang, Shangzu Yang, Gengqiang Wang, Xin Liu, Fuxian

机构：Gansu Univ Chinese Med;Gansu Inst Cardiovasc Dis;Minist Educ

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年165卷

JCR：一分区

影响因子：6.9

关键词：Energy metabolism   Ischemic heart disease   Heart failure   Mitochondrion   Diabetic cardiomyopathy   Ischemia   reperfusion injury  

23Astragalus polysaccharide inhibits radiation-induced bystander effects by regulating apoptosis in Bone Mesenchymal Stem Cells (BMSCs)被引量：21收藏 分享

作者：Zhang, Yi-Ming Zhang, Li-Ying Zhou, Heng Li, Yang-Yang Wei, Kong-Xi

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci

来源：CELL CYCLE  2020年19卷22期

JCR：二分区

影响因子：4.534

关键词：APS   RIBE   BMSCs   Astragalus Polysaccharide   Bystander Effect   Apoptosis  

24The antioxidant effects of hedysarum polybotrys polysaccharide in extending lifespan and ameliorating aging-related diseases in Drosophila melanogaster被引量：21收藏 分享

作者：Yang, Shipei Xiu, Minghui Li, Xu Shi, Yan Wang, Shuwei

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Minist Educ

来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  2023年241卷

JCR：一分区

影响因子：7.7

关键词：Hedysarum polybotrys polysaccharide   Anti-aging   Intestinal homeostasis   Sleep disturbances   Alzheimer's disease   Drosophila melanogaster  

25Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-κB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs)被引量：21收藏 分享

作者：Zhang, Liying Luo, Yali Lu, Zhiwei He, Jinpeng Wang, Lei

机构：Gansu Univ Tradit Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Tradit Chinese Med

来源：MEDICAL SCIENCE MONITOR  2018年24卷

影响因子：1.98

关键词：Bystander Effect   Mesenchymal Stromal Cells   Polysaccharides  

26Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer被引量：19收藏 分享

作者：Li, Ling Jin, Xiao-jie Li, Jia-wei Li, Cheng-hao Zhou, Shuang-yan

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Chongqing Univ Posts & Telecommun;Gansu Univ Chinese Med

来源：CANCER SCIENCE  2021年112卷5期

JCR：二分区

影响因子：6.518

关键词：gastric cancer   Guiqi Baizhu prescription   molecular docking   molecular dynamics simulation   MST analysis   network pharmacology  

27Guiqi Baizhu Decoction Alleviates Radiation Inflammation in Rats by Modulating the Composition of the Gut Microbiota被引量：17收藏 分享

作者：Zhang, Li-Ying Zhou, Ting Zhang, Yi-Ming Xu, Xiao-Min Li, Yang-Yang

机构：Gansu Univ Chinese Med;Chinese Acad Sci;Chinese Acad Sci;Gansu Univ Chinese Med

来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE  2020年2020卷

JCR：三分区

影响因子：2.63

28Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 pathways被引量：17收藏 分享

作者：Li, Botong Xiu, Minghui He, Li Zhou, Shihong Yi, Simeng

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;China Agr Univ

来源：JOURNAL OF ETHNOPHARMACOLOGY  2024年322卷

JCR：一分区

影响因子：4.8

关键词：San huang pill   Dunhuang ancient medical prescription   Ulcerative colitis   Drosophila melanogaster   Signaling pathway   Bioactive compounds  

29Exposure to cytarabine causes side effects on adult development and physiology and induces intestinal damage via apoptosis in Drosophila被引量：16收藏 分享

作者：Han, Shuzhen Xiu, Minghui Li, Shuang Shi, Yan Wang, Xiaoqian

机构：Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med;Gansu Univ Chinese Med

来源：BIOMEDICINE & PHARMACOTHERAPY  2023年159卷

JCR：一分区

影响因子：6.9

关键词：Cytarabine   Side effects   Drosophila melanogaster   Intestine   Apoptosis  

30Antitumor effect of IL-12 gene-modified bone marrow mesenchymal stem cells combined with Fuzheng Yiliu decoction in an in vivo glioma nude mouse model被引量：16收藏 分享

作者：Wu, Jianjun Xie, Shoupin Li, Hailong Zhang, Yanxia Yue, Jia

机构：Gansu Univ Chinese Med;Key Lab Dunhuang Med & Transformat & Prov & Minis;Prov Key Lab Chinese Med Prevent & Control Chron;First Peoples Hosp Lanzhou City;Gansu Univ Chinese Med

来源：JOURNAL OF TRANSLATIONAL MEDICINE  2021年19卷1期

JCR：一分区

影响因子：8.448

关键词：Bone marrow mesenchymal stem cell   Glioma   IL-12   Fuzheng Yiliu decoction